List of Research Reports with Shibayagi's Assay Kits
Contents
Human Apo B-48 ELISA KIT(AKHB-48)Human Nesfatin-1 ELISA KIT(AKHNF1-050)
Rat Insulin ELISA KIT(AKRIN-010)
Rat Insulin ELISA KIT (TMB) (AKRIN-010T)
Rat Insulin ELISA KIT (H-type) (AKRIN-010H)
Rat Insulin ELISA KIT (U-type) (AKRIN-030)
Rat Insulin ELISA KIT (U-E type) (AKRIN-130)
Mouse Insulin ELISA KIT (AKRIN-011)
Mouse Insulin ELISA KIT (TMB) (AKRIN-011T)
Mouse Insulin ELISA KIT (H-type) (AKRIN-011H)
Mouse Insulin ELISA KIT (U-type) (AKRIN-031)
Mouse Insulin ELISA KIT (S-type) (AKRIN-011S)
Dog Insulin ELISA KIT (AKRIN-012T)
Monkey Insulin ELISA KIT (AKRIN-014T)
Rabbit Insulin Standard (ASIN-003)
Cat Insulin ELISA KIT (AKRIN-015)
Mouse C-peptide ELISA KIT (U-type)(AKRCP-031)
Rat C-peptide ELISA KIT (U-type)(AKRCP-030)
GLP-1(Active) ELISA KIT(AKMGP-011)
Apolipoprotein B48 ELISA kits (AKHB48)
Rat Leptin ELISA KIT(U type)(AKRLP-010)
Mouse Leptin ELISA KIT(AKRLP-011)
Mouse Resistin ELISA KIT(AKRRS-011)
Mouse TNF a ELISA KIT(AKMTN-011)
Mouse/Rat High Molecular Weight Adiponectin ELISA KIT(AKMAN-011)
Mouse Anti-dsDNA antibody ELISA kit (AKRDD-061)
Mouse Anti-ssDNA antibody ELISA kit (AKRSD-051)
Mouse Rheumatoid Factor IgG Type ELISA Kit (AKRRG-101)
Mouse Rheumatoid Factor IgM Type ELISA Kit (AKRRG-111)
OVA IgE ELISA KIT (AKRIE-030)
Rabbit CRP ELISA kit (AKRCR-017)
Mouse IgE ELISA kit (AKRIE-010)
Rat IgE ELISA kit (AKRIE-011)
Rat albumin TIA kit (AKRAL-020)
Mouse albumin ELISA kit (AKRAL-120)
Rat albumin ELISA kit (AKRAL-121)
Bovinealbumin ELISA kit (AKRBS-018)
Rat GH ELISA KIT(AKRGH-010)
Rat TSH ELISA kit (AKRTS-010)
Mouse SAA ELISA kit (AKRSA-011SW)
Assay & research materials supply
Human Apo B-48 ELISA KIT(AKHB-48)
Original reports
# The characteristics of remnantlipoproteins in the fasting andpostprandialplasma the fasting andpostprandialplasma
Katsuyuki Nakajima, Takamitsu Nakano, Yoshiharu Tokita, Takeaki Nagamine, Shin-ichi Yatsuzuka, Younosuke Shimomura, Akira Tanaka, Hiroyuki Sumino, Makoto Nara, Tetsuo Machida, Masami Murakami
Clinica Chimica Acta 2012, In Press
# Exenatide, a Glucagon-like Peptide Receptor Agonist,
Acutely Inhibits Intestinal LipoproteinProduction in Healthy Humans
Xiao C, Bandsma RH, Dash S, Szeto L, Lewis GF.
Arterioscler Thromb Vasc Biol. 2012 Apr 5.
# Lowering of postprandial lipids in individuals with type 2 diabetes treated with alogliptin and/or pioglitazone: a randomised double-blind placebo-controlled study
Eliasson B, Möller-Goede D, Eeg-Olofsson K, Wilson C, Cederholm J, Fleck P, Diamant M, Taskinen MR, Smith U.
Diabetologia. 2012 Apr;55(4):915-25.
# Unacylated Ghrelin is associated with the isolated low HDL-cholesterol obese phenotypeindependently of insulin resistance and CRP level
Nogueira JP, Maraninchi M, Béliard S, Lorec AM, Berthet B, Bégu-Le Corroller A, Dubois N, Grangeot R, Mattei C, Gaudart J, Nicolay A, Portugal H, Vialettes B,Valéro R.
Nutr Metab (Lond). 2012 Mar 13;9(1):17.
# Effect of short-term low- and high-fat diets on low-density lipoprotein particle size in normolipidemic subjects.
Guay V, Lamarche B, Charest A, Tremblay AJ, Couture P
Metabolism. 2012 Jan;61(1):76-83.
# Fasting APO B48 levels are associated with microalbuminuria in patients with type 2 diabetes
E. Lapice, P. Cipriano, L. Patti, G. Romano, O. Vaccaro and A. A. Rivellese
ACTA DIABETOLOGICA 2012, DOI: 10.1007/s00592-012-0386-1
# Exploring the value of apoB48 as a marker for atherosclerosis in clinical practice
Arash Alipour, Pedro Valdivielso, Jan Willem F. Elte, HansW. Janssen, Jose Rioja, Noe lle van der Meulen, Rob van Mechelen, Tjin L. Njo, Pedro Gonza´ lez-Santos, Arie P. Rietveld, Manuel Castro Cabezas
Eur J Clin Invest. 2011 Dec 2; DOI: 10.1111/j.1365-2362.2011.02635.x
# Effect of Omega-3 Fatty Acids on Low Density Lipoprotein Subfraction, Adiponectin and Apolipoprotein B in Type 2 Diabetic Patients
Jun H, Ko J, Jung H, Yoon C, Kim T, Kwon M, Lee S, Suk J, Kim M, Kim D, Park JH.
Endocrinol Metab. 2011 Sep 26(3):218-224.
# Diet-induced dyslipidemia impairs reverse cholesterol transport in hamsters
Tréguier M, Briand F, Boubacar A, André A, Magot T, Nguyen P, Krempf M, Sulpice T, Ouguerram K.
Eur J Clin Invest. 2011 Sep;41(9):921-8.
# Ezetimibe beneficiallyinfluencesfastingandpostprandialtriglyceride-rich lipoproteins intype2diabetes
Bozzetto L, Annuzzi G, Corte GD, Patti L, Cipriano P, Mangione A, Riccardi G, Rivellese AA.
Atherosclerosis. 2011 Jul;217(1):142-8
# Postprandial lipoprotein metabolism: VLDL vs chylomicrons
Nakajima K, Nakano T, Tokita Y, Nagamine T, Inazu A, Kobayashi J, Mabuchi H, Stanhope KL, Havel PJ, Okazaki M, Ai M, Tanaka A.
Clin Chim Acta. 2011 Jul 15;412(15-16):1306-18.
# Protocol for the measurement of fatty acid and glycerol turnover in vivo in baboons
Raul A. Bastarrachea, Sonya M. Veron, Vidya Vaidyanathan, Maggie Garcia-Forey, V. Saroja Voruganti, Paul B. Higgins, Elizabeth J. Parks
J Lipid Res. 2011 Jun;52(6):1272-80
# Effects of acute hyperglucagonemia on hepatic and intestinal Lipoprotein production and clearancein healthy humans
Xiao C, Pavlic M, Szeto L, Patterson BW, Lewis GF.
Diabetes. 2011 Feb;60(2):383-90.
# Resistance exercise but not aerobic exercise lowers remnant-like lipoprotein particle cholesterol in type 2 diabetes: a randomized controlled trial.
Gavin C, Sigal RJ, Cousins M, Menard ML, Atkinson M, Khandwala F, Kenny GP, Proctor S, Ooi TC; Diabetes Aerobic and Resistance Exercise (DARE) trial investigators.
Atherosclerosis. 2010 Dec;213(2):552-7.
# Postprandial lipid and apolipoprotein responses following three consecutive meals associate withliver fat content in type 2 diabetes and the metabolic syndrome
Tushuizen ME, Pouwels PJ, Bontemps S, Rustemeijer C, Matikainen N, Heine RJ, Taskinen MR, Diamant M.
Atherosclerosis. 2010 Jul;211(1):308-14.
# Chylomicronemia with low postheparin lipoprotein lipase levels in the setting of GPIHBP1 defects
Franssen R, Young SG, Peelman F, Hertecant J, Sierts JA, Schimmel AW, Bensadoun A, Kastelein JJ, Fong LG, Dallinga-Thie GM, Beigneux AP
Circ Cardiovasc Genet. 2010 Apr;3(2):169-78.
# Atorvastatin increases intestinal expression of NPC1L1 in hyperlipidemic men
Tremblay, A.J, Lamarche, B., Lemelin, V., Hoos, L., Benjannet, S., Seidah, N.G., Davis Jr., H.R., and Couture, P.
The Journal of Lipid Research 52: 558-868, 2011
# Effect of Sitagliptin Therapy on Postprandial Lipoprotein Levels in Patients with Type 2 Diabetes
Tremblay, A.J., Lamarche, B., Deacon, C.F., Weisnagel, S.J. and Couture, P.
Diabetes, Obesity and Metabolism 13 (4): 366-373, 2011
# Particle Size of ApoB-48 Carrying Lipoproteins in Remnant Lipoproteins Isolated from Postprandial Plasma
Nakano, T., Tanaka, A., Okazaki, M., Tokita, Y., Nagamine, T. and Nakajima, K.
Ann Clin Biochem 2011; 48: 57-64
# Jejunal Wall Triglyceride Concentration of Morbidly Obese Persons Is Lower in Those with Type 2 Diabetes Mellitus
Soriguer, F., Garcia-Serrano, S., Garrido-Sanchez, L., Gutirrez-Repiso, C., Rojo-Martinez, G., Garcia-Escobar, E., Garcis-Arnes, J., Gallego-Perales, JL., Delgano, V. and Garcia-Fuentes, E.
J Lipid Res. 2010 Dec; 51 (12): 3516-23
# Effect of Low Concentration of Diacylglycerol on Mildly Postprandial Hypertriglyceridemia
Saito, S., Yamaguchi, T., Shoji, K., Hibi, M., Sugita, T. and Takase, H.
Atherosclerosis 213 (2): 539-544
# Insulin Acutely Inhibits Intestinal Lipoprotein Secretion in Human in Part by Suppressing Plasma Free Fatty Acids
Pavlic, M., Xiao, C., Szeto, L., Patterson, B.W. and Lewis, G.F.
Diabetes, Vol. 59 (3): 580-287, 2010
#Increased Serum Apolipoprotein B48 Concentration in Patients with Metabolic Syndrome
Kinoshita,M.,Ohnishi,H.,Maeda,T.,Yoshimura,N.,Takeoka,Y.,Yasuda,D.,Kusano,J.,Mashimo,Y.,
Saito,S.,Shimamoto,K.and Teramoto,T.
Jpurnal of Atherosclerosis and Thrombosis Vol.16:517-522.2009
# Familial Combined Hyperlipidemia Is Associated With Alterations in the Cholesterol Synthesis Pathway
Himbergen, T. M., Otokozawa, S., Matthan, N. R., Schaefer, E. J., Buchsbaum, A., Ai, M., Tits, L. J. H., Graaf, J., Stalenhoef, A. F. H.
Arterioscler Thromb Vasc Biol, 30: 113-120, 2010
# Postprandial apolipoprotein B48 is associated with asymptomatic peripheral arterial disease: A study in patients with type 2 diabetes and controls
Valdivielso, P., Puerta, S., Rioja, J., Alonso, I., Ariza, M. J., Sanchez-Chaparro, M. A., Palacios, R., Gonzalez-Santos, P.
Clinica Chimica Acta, Volume 411, Issues 5-6, 2 March, 2010, 433-437
# Chylomicronemia With a Mutant GPIHBP1 (Q115P) That Cannot Bind Lipoprotein Lipase
Beigneux, A. P., Franssen, R., Bensadoun, A., Gin, P., Melford. K., Peter, J., Walzem, R. L., Weinstein, M. M., Davies, B. S. J., Kuivenhoven, J. A., Kastelein, J. J. P., Fong, L. G., Dallinga-Thie, G. M., Young, A. G.
Arterioscler Thromb Vasc Biol, 29: 956-962, 2009
# Omega 3 fatty acids induce a markerd reduction of
apolipoprotein B48 when added to fluvastatin in
patients with type 2 diabetes and mixed hyperlipidemia
Valdivielso,P.,Rioja,J.,Garcia-Arias,C.,Sanchez-Chaparro,MA.,Gonzalez-Santos,P.
Cardiovasc Diabetol,8;8:1,2009
# Fasting and postprandial apolipoprotein B-48 levels in healthy,obese,and hyperlipidemic subjects
Otokozawa,S.,Ai,M., Diffenderfer,MR., Asztalos,BF.,Tanaka,A., Lamon-Fava,S., Schaefer,EJ.
Metabolism Clinical and Experimental . Volume 58, Issues 11, November, 2009, 1536-1542
#Detection of apolipoprotein B-48 and B-100 carrying particles in lipoprotein fractions extracted from human aortic atherosclerotic plaques in sudden cardiac death cases.
Nakano, T., Nakajima, K., Niimi, M., Fujita, M.Q., Nakajima, Y., Takeichi, S, Kinoshita, M., Matsushima, T., Teramoto, T., and Tanaka, A.
Clinica Chimica Acta 390, 38-43, 2008.
#Plasma fasting and postprandial apolipoprotein B48 are increased only
in type2 diabetes with atherosclerosclerosis
P.Valdivielso,J.Rioja,S.Puerta,M.J.Ariza-Corbo,M.A.Sanchez-Chaparro,
I.Alonso and P.Gonzalez-Santos
Atherosclerosis Supplements Vol.9,issue2,September 2008,87-88
# Postprandial Hyperlipidemia and Atherosclerosis
Teramoto, T.
Atherosclerosis Supplements 9, 83-102, 2008
# Decreased lipoprotein lipase activity and increased postprandial concentrations of triglyceride-rich lipoproteins in offspring of elderly survivors of myocardial infarction.
Lakhal, S., Borvik, T., Nordoy, A., and Hansen, J.B.
Nutrition, Metabolism and Cardiovascular Diseases (Epub ahead of print), 2008
#Effects of Intensive Atorvastatin,Rosuvastatin Treatment on Apolipoprotein
B-48 and Remnant Lipoprotein Cholesterol Levels Seiko Otokozawa,Masumi Ai,Thomas Van Himbergen,Bela F.Asztalos,Akira Tanaka,
Evan A.Stein,Peter H.Jones and Ernst J.Schaefer
Atheroscleroisis,In Press,Accepted Manuscript,Available online 12 November 2008
#Extended-Release Niacin Alters the Metabolism of Plasma Apolipoprotein(Apo)A-I-and
ApoB-Containing Lipoproteins.
Lamon-Fava S,Diffenderfer MR,Barrett PH,Buchsbaum A,Nyaku M,Horvath KV,Asztalos BF,
Otokozawa S,Ai M,Matthan NR,Lichtenstein AH,Dolnikowski GG,Schaefer EJ.
Arterioscler Thromb Vasc Biol.2008 Jun 19.
#ApoB-100 carrying lipoprotein, but not apoB-48, is the major subset of proatherogenic remnant-like lipoprotein particles detected in plasma of sudden cardiac death cases.
Nakajima, K., Nakajima, Y., Takeichi, S., and Fijita, M.Q.
Atherosclerosis 194, 473-482, 2007.
# Involvement of intestinal alkaline phosphatase in serum apolipoprotein B-48 level and its association with ABO and secretor blood group types
Nakano, T., Shimanuki, T., Matsushita, M., Koyama, I., Inoue, I., Katayama, S., Alpers, D. H., Komoda, T.
Biochemical and Biophysical Research Communications, 341, 33-38, 2006
# Determination of apolipoprotein B-48 in serum by a sandwich ELISA
Kinoshita, M., Kojima, M., Matsushima, T., and Teramoto, T.
Clinica Chimaca Acta, 351, 115-120, 2005.
Presentations at scientific meetings
# Fasting and Postprandial Apo-B48 are Increased in Patients with Type 2 diabetes with Atherosclerosis
Valdivielso, P., Puerta, S., Rioja, J., Ariza, M., Hornos, A., Garcia-Arias, C., Sanchez-Chaparro, M., Gonzalez-Santos, P.(Univ. of Malaga)
77th Congress of the European Atherosclerosis Society, April 26-29, 2008, Istanbul, Turkey, Poster sessions, PO20-228
# Reduced Postprandial Concentration of Apolipoprotein B-48 with Camelina Oil
Vaananen, M., Ahotupa, M., Vasankari, T. M., Vasankari, T. J.(University of Turku)
76th Congress of the European Atherosclerosis Society, June 10-13, 2007, Helsinki, Finland, Poster sessions, PO20-619
# Apolipoprotein B-48 in Lipoprotein Fraction Extracted from Human Aortic Plaque and Plasma from Sudden Cardiac Death Cases
Nakano, T., Niimi, M., Nakajima, K., Fujita, M., Nakajima, Y., Takeichi, S., Tanaka, A., Matsushima, T., Kinoshita, M,. Teramoto, T.
(Jimro Co., Ltd., Keio Univ., Tokai Univ., Kagawa Nutrition Univ., Tsukuba Memorial Hospital., Teikyo Univ.)
76th Congress of the European Atherosclerosis Society, June 10-13, 2007, Helsinki, Finland, Poster sessions, PO3-63
# Concentration of Apolipoprotein B48 in Fasting Serum is an Important Marker of Postrandial Hyperlipidemia
Takenaka, H., Kinoshita, H., Maeda, T., Taki, M., Takao, K., Kusano, J., Yoshimura, N., Fujita, M., Teramoto, T.(Teikyo Univ. Sch. Of Med.)
XIV International Symposium on Atherosclerosis, Rome, Italy, June 18-22, 2006 Poster Session, Th-P15:76
# Concentration of apolipoprotein B48 in fasting serum is an important marker of postprandial hyperlipidemia.
Hirota, D., Kinosita, M., Maeda, T., suda, T., Taki, M., Kusano, J., Takenaka, H., Yoshimura,
N., and Teramoto, T.(Teikyo Univ. Sch. of Med. Int. Med.)
The 37th Japan Atherosclerosis Society Annual Meeting, 2005, English session ES-J8,Proceeding p.185
# The characteristics of remnantlipoproteins in the fasting andpostprandialplasma the fasting andpostprandialplasma
Katsuyuki Nakajima, Takamitsu Nakano, Yoshiharu Tokita, Takeaki Nagamine, Shin-ichi Yatsuzuka, Younosuke Shimomura, Akira Tanaka, Hiroyuki Sumino, Makoto Nara, Tetsuo Machida, Masami Murakami
Clinica Chimica Acta 2012, In Press
# Exenatide, a Glucagon-like Peptide Receptor Agonist,
Acutely Inhibits Intestinal LipoproteinProduction in Healthy Humans
Xiao C, Bandsma RH, Dash S, Szeto L, Lewis GF.
Arterioscler Thromb Vasc Biol. 2012 Apr 5.
# Lowering of postprandial lipids in individuals with type 2 diabetes treated with alogliptin and/or pioglitazone: a randomised double-blind placebo-controlled study
Eliasson B, Möller-Goede D, Eeg-Olofsson K, Wilson C, Cederholm J, Fleck P, Diamant M, Taskinen MR, Smith U.
Diabetologia. 2012 Apr;55(4):915-25.
# Unacylated Ghrelin is associated with the isolated low HDL-cholesterol obese phenotypeindependently of insulin resistance and CRP level
Nogueira JP, Maraninchi M, Béliard S, Lorec AM, Berthet B, Bégu-Le Corroller A, Dubois N, Grangeot R, Mattei C, Gaudart J, Nicolay A, Portugal H, Vialettes B,Valéro R.
Nutr Metab (Lond). 2012 Mar 13;9(1):17.
# Effect of short-term low- and high-fat diets on low-density lipoprotein particle size in normolipidemic subjects.
Guay V, Lamarche B, Charest A, Tremblay AJ, Couture P
Metabolism. 2012 Jan;61(1):76-83.
# Fasting APO B48 levels are associated with microalbuminuria in patients with type 2 diabetes
E. Lapice, P. Cipriano, L. Patti, G. Romano, O. Vaccaro and A. A. Rivellese
ACTA DIABETOLOGICA 2012, DOI: 10.1007/s00592-012-0386-1
# Exploring the value of apoB48 as a marker for atherosclerosis in clinical practice
Arash Alipour, Pedro Valdivielso, Jan Willem F. Elte, HansW. Janssen, Jose Rioja, Noe lle van der Meulen, Rob van Mechelen, Tjin L. Njo, Pedro Gonza´ lez-Santos, Arie P. Rietveld, Manuel Castro Cabezas
Eur J Clin Invest. 2011 Dec 2; DOI: 10.1111/j.1365-2362.2011.02635.x
# Effect of Omega-3 Fatty Acids on Low Density Lipoprotein Subfraction, Adiponectin and Apolipoprotein B in Type 2 Diabetic Patients
Jun H, Ko J, Jung H, Yoon C, Kim T, Kwon M, Lee S, Suk J, Kim M, Kim D, Park JH.
Endocrinol Metab. 2011 Sep 26(3):218-224.
# Diet-induced dyslipidemia impairs reverse cholesterol transport in hamsters
Tréguier M, Briand F, Boubacar A, André A, Magot T, Nguyen P, Krempf M, Sulpice T, Ouguerram K.
Eur J Clin Invest. 2011 Sep;41(9):921-8.
# Ezetimibe beneficiallyinfluencesfastingandpostprandialtriglyceride-rich lipoproteins intype2diabetes
Bozzetto L, Annuzzi G, Corte GD, Patti L, Cipriano P, Mangione A, Riccardi G, Rivellese AA.
Atherosclerosis. 2011 Jul;217(1):142-8
# Postprandial lipoprotein metabolism: VLDL vs chylomicrons
Nakajima K, Nakano T, Tokita Y, Nagamine T, Inazu A, Kobayashi J, Mabuchi H, Stanhope KL, Havel PJ, Okazaki M, Ai M, Tanaka A.
Clin Chim Acta. 2011 Jul 15;412(15-16):1306-18.
# Protocol for the measurement of fatty acid and glycerol turnover in vivo in baboons
Raul A. Bastarrachea, Sonya M. Veron, Vidya Vaidyanathan, Maggie Garcia-Forey, V. Saroja Voruganti, Paul B. Higgins, Elizabeth J. Parks
J Lipid Res. 2011 Jun;52(6):1272-80
# Effects of acute hyperglucagonemia on hepatic and intestinal Lipoprotein production and clearancein healthy humans
Xiao C, Pavlic M, Szeto L, Patterson BW, Lewis GF.
Diabetes. 2011 Feb;60(2):383-90.
# Resistance exercise but not aerobic exercise lowers remnant-like lipoprotein particle cholesterol in type 2 diabetes: a randomized controlled trial.
Gavin C, Sigal RJ, Cousins M, Menard ML, Atkinson M, Khandwala F, Kenny GP, Proctor S, Ooi TC; Diabetes Aerobic and Resistance Exercise (DARE) trial investigators.
Atherosclerosis. 2010 Dec;213(2):552-7.
# Postprandial lipid and apolipoprotein responses following three consecutive meals associate withliver fat content in type 2 diabetes and the metabolic syndrome
Tushuizen ME, Pouwels PJ, Bontemps S, Rustemeijer C, Matikainen N, Heine RJ, Taskinen MR, Diamant M.
Atherosclerosis. 2010 Jul;211(1):308-14.
# Chylomicronemia with low postheparin lipoprotein lipase levels in the setting of GPIHBP1 defects
Franssen R, Young SG, Peelman F, Hertecant J, Sierts JA, Schimmel AW, Bensadoun A, Kastelein JJ, Fong LG, Dallinga-Thie GM, Beigneux AP
Circ Cardiovasc Genet. 2010 Apr;3(2):169-78.
# Atorvastatin increases intestinal expression of NPC1L1 in hyperlipidemic men
Tremblay, A.J, Lamarche, B., Lemelin, V., Hoos, L., Benjannet, S., Seidah, N.G., Davis Jr., H.R., and Couture, P.
The Journal of Lipid Research 52: 558-868, 2011
# Effect of Sitagliptin Therapy on Postprandial Lipoprotein Levels in Patients with Type 2 Diabetes
Tremblay, A.J., Lamarche, B., Deacon, C.F., Weisnagel, S.J. and Couture, P.
Diabetes, Obesity and Metabolism 13 (4): 366-373, 2011
# Particle Size of ApoB-48 Carrying Lipoproteins in Remnant Lipoproteins Isolated from Postprandial Plasma
Nakano, T., Tanaka, A., Okazaki, M., Tokita, Y., Nagamine, T. and Nakajima, K.
Ann Clin Biochem 2011; 48: 57-64
# Jejunal Wall Triglyceride Concentration of Morbidly Obese Persons Is Lower in Those with Type 2 Diabetes Mellitus
Soriguer, F., Garcia-Serrano, S., Garrido-Sanchez, L., Gutirrez-Repiso, C., Rojo-Martinez, G., Garcia-Escobar, E., Garcis-Arnes, J., Gallego-Perales, JL., Delgano, V. and Garcia-Fuentes, E.
J Lipid Res. 2010 Dec; 51 (12): 3516-23
# Effect of Low Concentration of Diacylglycerol on Mildly Postprandial Hypertriglyceridemia
Saito, S., Yamaguchi, T., Shoji, K., Hibi, M., Sugita, T. and Takase, H.
Atherosclerosis 213 (2): 539-544
# Insulin Acutely Inhibits Intestinal Lipoprotein Secretion in Human in Part by Suppressing Plasma Free Fatty Acids
Pavlic, M., Xiao, C., Szeto, L., Patterson, B.W. and Lewis, G.F.
Diabetes, Vol. 59 (3): 580-287, 2010
#Increased Serum Apolipoprotein B48 Concentration in Patients with Metabolic Syndrome
Kinoshita,M.,Ohnishi,H.,Maeda,T.,Yoshimura,N.,Takeoka,Y.,Yasuda,D.,Kusano,J.,Mashimo,Y.,
Saito,S.,Shimamoto,K.and Teramoto,T.
Jpurnal of Atherosclerosis and Thrombosis Vol.16:517-522.2009
# Familial Combined Hyperlipidemia Is Associated With Alterations in the Cholesterol Synthesis Pathway
Himbergen, T. M., Otokozawa, S., Matthan, N. R., Schaefer, E. J., Buchsbaum, A., Ai, M., Tits, L. J. H., Graaf, J., Stalenhoef, A. F. H.
Arterioscler Thromb Vasc Biol, 30: 113-120, 2010
# Postprandial apolipoprotein B48 is associated with asymptomatic peripheral arterial disease: A study in patients with type 2 diabetes and controls
Valdivielso, P., Puerta, S., Rioja, J., Alonso, I., Ariza, M. J., Sanchez-Chaparro, M. A., Palacios, R., Gonzalez-Santos, P.
Clinica Chimica Acta, Volume 411, Issues 5-6, 2 March, 2010, 433-437
# Chylomicronemia With a Mutant GPIHBP1 (Q115P) That Cannot Bind Lipoprotein Lipase
Beigneux, A. P., Franssen, R., Bensadoun, A., Gin, P., Melford. K., Peter, J., Walzem, R. L., Weinstein, M. M., Davies, B. S. J., Kuivenhoven, J. A., Kastelein, J. J. P., Fong, L. G., Dallinga-Thie, G. M., Young, A. G.
Arterioscler Thromb Vasc Biol, 29: 956-962, 2009
# Omega 3 fatty acids induce a markerd reduction of
apolipoprotein B48 when added to fluvastatin in
patients with type 2 diabetes and mixed hyperlipidemia
Valdivielso,P.,Rioja,J.,Garcia-Arias,C.,Sanchez-Chaparro,MA.,Gonzalez-Santos,P.
Cardiovasc Diabetol,8;8:1,2009
# Fasting and postprandial apolipoprotein B-48 levels in healthy,obese,and hyperlipidemic subjects
Otokozawa,S.,Ai,M., Diffenderfer,MR., Asztalos,BF.,Tanaka,A., Lamon-Fava,S., Schaefer,EJ.
Metabolism Clinical and Experimental . Volume 58, Issues 11, November, 2009, 1536-1542
#Detection of apolipoprotein B-48 and B-100 carrying particles in lipoprotein fractions extracted from human aortic atherosclerotic plaques in sudden cardiac death cases.
Nakano, T., Nakajima, K., Niimi, M., Fujita, M.Q., Nakajima, Y., Takeichi, S, Kinoshita, M., Matsushima, T., Teramoto, T., and Tanaka, A.
Clinica Chimica Acta 390, 38-43, 2008.
#Plasma fasting and postprandial apolipoprotein B48 are increased only
in type2 diabetes with atherosclerosclerosis
P.Valdivielso,J.Rioja,S.Puerta,M.J.Ariza-Corbo,M.A.Sanchez-Chaparro,
I.Alonso and P.Gonzalez-Santos
Atherosclerosis Supplements Vol.9,issue2,September 2008,87-88
# Postprandial Hyperlipidemia and Atherosclerosis
Teramoto, T.
Atherosclerosis Supplements 9, 83-102, 2008
# Decreased lipoprotein lipase activity and increased postprandial concentrations of triglyceride-rich lipoproteins in offspring of elderly survivors of myocardial infarction.
Lakhal, S., Borvik, T., Nordoy, A., and Hansen, J.B.
Nutrition, Metabolism and Cardiovascular Diseases (Epub ahead of print), 2008
#Effects of Intensive Atorvastatin,Rosuvastatin Treatment on Apolipoprotein
B-48 and Remnant Lipoprotein Cholesterol Levels Seiko Otokozawa,Masumi Ai,Thomas Van Himbergen,Bela F.Asztalos,Akira Tanaka,
Evan A.Stein,Peter H.Jones and Ernst J.Schaefer
Atheroscleroisis,In Press,Accepted Manuscript,Available online 12 November 2008
#Extended-Release Niacin Alters the Metabolism of Plasma Apolipoprotein(Apo)A-I-and
ApoB-Containing Lipoproteins.
Lamon-Fava S,Diffenderfer MR,Barrett PH,Buchsbaum A,Nyaku M,Horvath KV,Asztalos BF,
Otokozawa S,Ai M,Matthan NR,Lichtenstein AH,Dolnikowski GG,Schaefer EJ.
Arterioscler Thromb Vasc Biol.2008 Jun 19.
#ApoB-100 carrying lipoprotein, but not apoB-48, is the major subset of proatherogenic remnant-like lipoprotein particles detected in plasma of sudden cardiac death cases.
Nakajima, K., Nakajima, Y., Takeichi, S., and Fijita, M.Q.
Atherosclerosis 194, 473-482, 2007.
# Involvement of intestinal alkaline phosphatase in serum apolipoprotein B-48 level and its association with ABO and secretor blood group types
Nakano, T., Shimanuki, T., Matsushita, M., Koyama, I., Inoue, I., Katayama, S., Alpers, D. H., Komoda, T.
Biochemical and Biophysical Research Communications, 341, 33-38, 2006
# Determination of apolipoprotein B-48 in serum by a sandwich ELISA
Kinoshita, M., Kojima, M., Matsushima, T., and Teramoto, T.
Clinica Chimaca Acta, 351, 115-120, 2005.
Presentations at scientific meetings
# Fasting and Postprandial Apo-B48 are Increased in Patients with Type 2 diabetes with Atherosclerosis
Valdivielso, P., Puerta, S., Rioja, J., Ariza, M., Hornos, A., Garcia-Arias, C., Sanchez-Chaparro, M., Gonzalez-Santos, P.(Univ. of Malaga)
77th Congress of the European Atherosclerosis Society, April 26-29, 2008, Istanbul, Turkey, Poster sessions, PO20-228
# Reduced Postprandial Concentration of Apolipoprotein B-48 with Camelina Oil
Vaananen, M., Ahotupa, M., Vasankari, T. M., Vasankari, T. J.(University of Turku)
76th Congress of the European Atherosclerosis Society, June 10-13, 2007, Helsinki, Finland, Poster sessions, PO20-619
# Apolipoprotein B-48 in Lipoprotein Fraction Extracted from Human Aortic Plaque and Plasma from Sudden Cardiac Death Cases
Nakano, T., Niimi, M., Nakajima, K., Fujita, M., Nakajima, Y., Takeichi, S., Tanaka, A., Matsushima, T., Kinoshita, M,. Teramoto, T.
(Jimro Co., Ltd., Keio Univ., Tokai Univ., Kagawa Nutrition Univ., Tsukuba Memorial Hospital., Teikyo Univ.)
76th Congress of the European Atherosclerosis Society, June 10-13, 2007, Helsinki, Finland, Poster sessions, PO3-63
# Concentration of Apolipoprotein B48 in Fasting Serum is an Important Marker of Postrandial Hyperlipidemia
Takenaka, H., Kinoshita, H., Maeda, T., Taki, M., Takao, K., Kusano, J., Yoshimura, N., Fujita, M., Teramoto, T.(Teikyo Univ. Sch. Of Med.)
XIV International Symposium on Atherosclerosis, Rome, Italy, June 18-22, 2006 Poster Session, Th-P15:76
# Concentration of apolipoprotein B48 in fasting serum is an important marker of postprandial hyperlipidemia.
Hirota, D., Kinosita, M., Maeda, T., suda, T., Taki, M., Kusano, J., Takenaka, H., Yoshimura,
N., and Teramoto, T.(Teikyo Univ. Sch. of Med. Int. Med.)
The 37th Japan Atherosclerosis Society Annual Meeting, 2005, English session ES-J8,Proceeding p.185
Human Nesfatin-1 ELISA KIT(AKHNF1-050)
Original reports
#Fasting concentrations of nesfatin-1 are negatively correlated with body mass index in non-obese males
T. Tsuchiya., H. Shimizu., M. Yamada., A. Osaki., S. Oh-i., Y. Ariyama., H. Takahashi., S. Okada., K. Hashimoto., T. Satoh., M. Kojima., M. Mori.
Clinical Endocrinology(2010)73,484-490
# Peripheral Administration of Nesfatin-1 Reduces Food intake in Mice: The Leptin-Independent Mechanism
Shimizu H, et al. ; Endocrinology 150: 662-671, 2009
# Identification of Nesfation-1 as a satiety molecule in the hypothalamus
Oh-I S, et al ; Nature 443: 709-712, 2006
#Fasting concentrations of nesfatin-1 are negatively correlated with body mass index in non-obese males
T. Tsuchiya., H. Shimizu., M. Yamada., A. Osaki., S. Oh-i., Y. Ariyama., H. Takahashi., S. Okada., K. Hashimoto., T. Satoh., M. Kojima., M. Mori.
Clinical Endocrinology(2010)73,484-490
# Peripheral Administration of Nesfatin-1 Reduces Food intake in Mice: The Leptin-Independent Mechanism
Shimizu H, et al. ; Endocrinology 150: 662-671, 2009
# Identification of Nesfation-1 as a satiety molecule in the hypothalamus
Oh-I S, et al ; Nature 443: 709-712, 2006
| Page top |
Rat Insulin ELISA KIT (AKRIN-010)
Original reports
# Additional Effect of Visceral Fat Resection in an Obese Rat Model of Gastric Banding
Endo, Y., Ohta, M., Hirashita, T., Eguchi, H., Kai, S. and Kitano, S.
Obesity Surgery, 10.1007/s11695-008-9313-9, 2008
# Improvement of islet culture with sericin
Ogawa, A. et al
J. Biosci. Bioeng., 98, 217-219, 2004
# Single-Allele Correction of The Dmo1 Locus In Congenic Animals Substantially Attenuates Obesity, Dyslipidaemia And Diabetes Phenotypes Of The Oletf Rat
Watanabe T.; Okuno S.; Ono T.; Yamasaki Y.; Oga K.; Mizoguchi-Miyakita A.; Miyao H.; Suzuki M.; Momota H.; Goto Y.; Shinomiya H.; Hishigaki H.; Hayashi I.; Asai T.; Wakitani S.; Takagi T.; Nakamura Y.; Tanigami A.
Clinical and Experimental Pharmacology and Physiology, Volume 28, 28-42(15) ,2003
# Effects of Dmo1 on obesity, dyslipidaemia and hyperglycaemia in the Otsuka Long Evans Tokushima Fatty strain
Okuno、S., Watanabe、T.K., Ono, T., Oga, K., Mizoguchi-Miyakita, A., Yamasaki, Y., Goto, Y., Shinomiya, H., Momota, H., Miyao, H., Hayashi, I., Asai, T., Suzuki, M., Harada, Y., Hishigaki, H., Wakitani, S., Takagi, T., Nakamura, Y., and Tanigami, A.
Genet. Res., Camb. 77, pp. 183-190. 2001
# Additional Effect of Visceral Fat Resection in an Obese Rat Model of Gastric Banding
Endo, Y., Ohta, M., Hirashita, T., Eguchi, H., Kai, S. and Kitano, S.
Obesity Surgery, 10.1007/s11695-008-9313-9, 2008
# Improvement of islet culture with sericin
Ogawa, A. et al
J. Biosci. Bioeng., 98, 217-219, 2004
# Single-Allele Correction of The Dmo1 Locus In Congenic Animals Substantially Attenuates Obesity, Dyslipidaemia And Diabetes Phenotypes Of The Oletf Rat
Watanabe T.; Okuno S.; Ono T.; Yamasaki Y.; Oga K.; Mizoguchi-Miyakita A.; Miyao H.; Suzuki M.; Momota H.; Goto Y.; Shinomiya H.; Hishigaki H.; Hayashi I.; Asai T.; Wakitani S.; Takagi T.; Nakamura Y.; Tanigami A.
Clinical and Experimental Pharmacology and Physiology, Volume 28, 28-42(15) ,2003
# Effects of Dmo1 on obesity, dyslipidaemia and hyperglycaemia in the Otsuka Long Evans Tokushima Fatty strain
Okuno、S., Watanabe、T.K., Ono, T., Oga, K., Mizoguchi-Miyakita, A., Yamasaki, Y., Goto, Y., Shinomiya, H., Momota, H., Miyao, H., Hayashi, I., Asai, T., Suzuki, M., Harada, Y., Hishigaki, H., Wakitani, S., Takagi, T., Nakamura, Y., and Tanigami, A.
Genet. Res., Camb. 77, pp. 183-190. 2001
| Page top |
Rat Insulin ELISA KIT (TMB) (AKRIN-010T)
Original reports
#A Comparative Study of Gastric Banding and Sleeve Gastrectomy in an Obese Diabetic Rat Model
T. Masuda., M. Ohta., T. Hirashita., Y. Kawano., H. Egucji., K. Yada., Y. Iwashita., S. Kitano
Obesity Surgery, Published online:27 August 2011
#Site dependency of fatty acid composition in adipose triacylglycerol in rats and its absence as a result of high-fat feeding
D. Sato., T. Nakamura., K. Tsutsumi., G. Shinzawa., T. Karimata., T. Okawa., Z. Fengc., and M. Kusunoki.
Metabolism.Article in Press
#Dietary fructo-oligosaccharides improve insulin sensitivity along with the suppression of adipocytokine secretion from mesenteric fat cells in rats
A. Shinoki., and H. Hara
British Journal of Nutrition.Published online :02 June 2011.
#Food restriction improves glucose and lipid metabolism through Sirt1 expression: A study using a new rat model with obesity and severe hypertension
K. Takemori.,T. Kimura.,N. Shirasaka.,T. Inoue.,K. Masuno., and H. Ito.
Life Sciences.Vol.88, Issues 25-26, 1088-1094. 2011
#Enhanced Urinary Bladder, Liver and Colon Carcinogenesis in Zucker Diabetic Fatty Rats in a Multiorgan Carcinogenesis Bioassay: Evidence for Mechanisms Involving Activation of PI3K Signaling and Impairment of P53 on Urinary Bladder Carcinogenesis
N. Ishii., M. Wei., A. Kakehashi., K. Doi., S. Yamano., M. Inaba., and H.Wanibuchi.
Journal of Toxicologic Pathology .Vol. 24 (2011) , No. 1 pp.25
#Maternal low-protein diet suppresses vascular and renal endothelial nitric oxide synthase phosphorylation in rat offspring independent of a postnatal fructose diet
S. Sato.,Y. Mukai., and T. Norikura.
Journal of Developmental Origins of Health and Disease (2011), 2: 168-175
#Combined Effects of Short-term Calorie Restriction and Exercise on Insulin Action in Normal Rats
H,Y,Jiang.,T,Koike.,P,Li.,Z,H,Wang.,Y,Kawata.,Y,Oshida.
Horm Metab Res 2010; 42(13): 950-954
#Dietary Hesperidin Exerts Hypoglycemic and Hypolipidemic Effects in Streptozocin-Induce Marginal Type 1 Diabetic Rats
Akiyama,S., Katsumata,S., Suzuki,K., Ishimi,Y.,Wu,J., and Uehara,M.
J Clin Biochem Nutr.January;46(1):87-92.2010
#Hypoglycemic and Hypolipidemic Effects of Hesperidin and Cyclodextrin-Clathrated Hesperetin in Goto-Kakizaki Rats with Type 2 Diabetes
Akiyama,S., Katsumata,S., Suzuki,K., Nakayama,Y., Ishimi,Y. and Uehara,M.
Bioscience,Biotechnology,and Biochemistry.Vol.73,No.12 pp.2779-2782(2009)
#Anti-Diabetic Effects of Pumpkin and Its Components,Trigonelline and
Nicotinic Acid,on Goto-Kakizaki Rats
Yoshinari,O.,Sato,H.and Igarashi,K.
Bioscience,Biotechnology,and Biochemistry.Vol.73,No5pp.1033-1041,2009
# Dietary Phosphatidylinositol Prevents the Development of Nonalcoholic Fatty Liver Disease in Zucker(fa/fa)Rats
Shirouchi,B.,Nagao,K.,Inoue,N.,Furuya,K.,Koga,S.,Matsumoto,H. and Yanagita,T.
J.Agric.Food Chem.56,2375-2379,2008
# Investigation of the anti-obesity action of licorice flavonoid oil in diet-induced obese rats.
Kamisoyama,H.,Honda,K.,Tominaga,Y.,Yokota,S.,Hasegawa,S.
Bioscience.Biotechnology. and Biochemistry 72.(12)3225-3231,2008
# Erythrophagocytosis by Liver Macrophages(Kupffer Cells)Promotes Oxidative Stress, Inflammation,and Fibrosis in a Rabbit Model of Steatohepatitis
Otogawa,K.,Kinoshita,K.,Fujii,H.,Sakabe,M.,Shiga,R.,Nakatani,K.,Ikeda,K.,Nakajima,Y.,
Ikura,Y.,Ueda,M.,Arakawa,T.,Hato,F., and Kawada,N.
American Journal of Pathology. 170:967-980, 2007
# Age- and sex-related diferences in spontaneous hemorrhage and fibrosis of the pancreatic islets in Sprague-Dawley rats.
Imaoka, M., Satoh, H. and Furuhama, K.
Toxicologic Pathology 35: 388-394, 2007
# Effect of 5-Campestenone (24-methylcholest-5-en-3-one) on Zucker Diabetic Fatty Rats as a Type 2 Diabetes Mellitus Model
R.Konno, Y.,Kaneko, K.,Suzuki, Y.,Matsui
Horm Metab Res ; 37(3): 79-83,2005
# Oxidized but not acetylated low-density lipoprotein reduces preproinsulin mRNA expression and secretion of insulin from HIT-T15 cells.
Okajima,F.,Kurihara,M.,Ono,C.,Nakajima,Y.,Tanimura,K.,Sugihara,H.,Ttsuguchi,A.,Nakagawa,K., Miyazawa,T.,and Oikawa,S.
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, Volume 1687, Issues 1-3, pp.173-180, 2005
# The role of calcium/calmodulin-dependent protein kinase cascade in glucose upregulation of insulin gene expression
Xiao Yu, Koji Murao, Yoshitaka Sayo, Hitomi Imachi, Wen M. Cao, Shouji Ohtsuka, Michio Niimi, Hiroshi Tokumitsu, Hiroyuki Inuzuka, Norman C.W. Wong, Ryoji Kobayashi, and Toshihiko Ishida
Diabetes, 53: 1475-1481, 2004
# PVA hydrogel sheet macroencapsulation for the bioartificial pancreas.
Qi M, Gu Y, Sakata N, Kim D, Shirouzu Y, Yamamoto C, Hiura A, Sumi S, Inoue K.
Biomaterials. 25: 5885-5892, 2004
# Alterations in vascular endothelial function in the aorta and mesenteric artery in type II diabetic rats
Takayuki Matsumoto, Kentaro Wakabayashi, Tsuneo Kobayashi, and Katsuo Kamata
Can. J. Physiol. Pharmacol. 82(3): 175-182, 2004
# Effect of eicosapentaenoic acid ethyl ester v. oleic acid-rich safflower
oil on insulin resistance in type 2 diabetic model rats with hypertriacylglycerolaemia
Asako Minami, Noriko Ishimura, Sadaichi Sakamoto, Eiko Takishita, Kazuaki Mawatari,
Kazuko Okada and Yutaka Nakaya
British J Nutrition 87, 157-162, 2002
# Evaluation of Insulin Secretion of Isolated Rat Islets Cultured in Extracellular Matrix
Nagata N.; Gu Y.; Hori H.; Balamurugan A.N.; Touma M.; Kawakami Y.; Wang W.; Baba T.T.; Satake A.; Nozawa M.; Tabata Y.; Inoue K.
Cell Transplantation, 10, 447-451, 2001
#A Comparative Study of Gastric Banding and Sleeve Gastrectomy in an Obese Diabetic Rat Model
T. Masuda., M. Ohta., T. Hirashita., Y. Kawano., H. Egucji., K. Yada., Y. Iwashita., S. Kitano
Obesity Surgery, Published online:27 August 2011
#Site dependency of fatty acid composition in adipose triacylglycerol in rats and its absence as a result of high-fat feeding
D. Sato., T. Nakamura., K. Tsutsumi., G. Shinzawa., T. Karimata., T. Okawa., Z. Fengc., and M. Kusunoki.
Metabolism.Article in Press
#Dietary fructo-oligosaccharides improve insulin sensitivity along with the suppression of adipocytokine secretion from mesenteric fat cells in rats
A. Shinoki., and H. Hara
British Journal of Nutrition.Published online :02 June 2011.
#Food restriction improves glucose and lipid metabolism through Sirt1 expression: A study using a new rat model with obesity and severe hypertension
K. Takemori.,T. Kimura.,N. Shirasaka.,T. Inoue.,K. Masuno., and H. Ito.
Life Sciences.Vol.88, Issues 25-26, 1088-1094. 2011
#Enhanced Urinary Bladder, Liver and Colon Carcinogenesis in Zucker Diabetic Fatty Rats in a Multiorgan Carcinogenesis Bioassay: Evidence for Mechanisms Involving Activation of PI3K Signaling and Impairment of P53 on Urinary Bladder Carcinogenesis
N. Ishii., M. Wei., A. Kakehashi., K. Doi., S. Yamano., M. Inaba., and H.Wanibuchi.
Journal of Toxicologic Pathology .Vol. 24 (2011) , No. 1 pp.25
#Maternal low-protein diet suppresses vascular and renal endothelial nitric oxide synthase phosphorylation in rat offspring independent of a postnatal fructose diet
S. Sato.,Y. Mukai., and T. Norikura.
Journal of Developmental Origins of Health and Disease (2011), 2: 168-175
#Combined Effects of Short-term Calorie Restriction and Exercise on Insulin Action in Normal Rats
H,Y,Jiang.,T,Koike.,P,Li.,Z,H,Wang.,Y,Kawata.,Y,Oshida.
Horm Metab Res 2010; 42(13): 950-954
#Dietary Hesperidin Exerts Hypoglycemic and Hypolipidemic Effects in Streptozocin-Induce Marginal Type 1 Diabetic Rats
Akiyama,S., Katsumata,S., Suzuki,K., Ishimi,Y.,Wu,J., and Uehara,M.
J Clin Biochem Nutr.January;46(1):87-92.2010
#Hypoglycemic and Hypolipidemic Effects of Hesperidin and Cyclodextrin-Clathrated Hesperetin in Goto-Kakizaki Rats with Type 2 Diabetes
Akiyama,S., Katsumata,S., Suzuki,K., Nakayama,Y., Ishimi,Y. and Uehara,M.
Bioscience,Biotechnology,and Biochemistry.Vol.73,No.12 pp.2779-2782(2009)
#Anti-Diabetic Effects of Pumpkin and Its Components,Trigonelline and
Nicotinic Acid,on Goto-Kakizaki Rats
Yoshinari,O.,Sato,H.and Igarashi,K.
Bioscience,Biotechnology,and Biochemistry.Vol.73,No5pp.1033-1041,2009
# Dietary Phosphatidylinositol Prevents the Development of Nonalcoholic Fatty Liver Disease in Zucker(fa/fa)Rats
Shirouchi,B.,Nagao,K.,Inoue,N.,Furuya,K.,Koga,S.,Matsumoto,H. and Yanagita,T.
J.Agric.Food Chem.56,2375-2379,2008
# Investigation of the anti-obesity action of licorice flavonoid oil in diet-induced obese rats.
Kamisoyama,H.,Honda,K.,Tominaga,Y.,Yokota,S.,Hasegawa,S.
Bioscience.Biotechnology. and Biochemistry 72.(12)3225-3231,2008
# Erythrophagocytosis by Liver Macrophages(Kupffer Cells)Promotes Oxidative Stress, Inflammation,and Fibrosis in a Rabbit Model of Steatohepatitis
Otogawa,K.,Kinoshita,K.,Fujii,H.,Sakabe,M.,Shiga,R.,Nakatani,K.,Ikeda,K.,Nakajima,Y.,
Ikura,Y.,Ueda,M.,Arakawa,T.,Hato,F., and Kawada,N.
American Journal of Pathology. 170:967-980, 2007
# Age- and sex-related diferences in spontaneous hemorrhage and fibrosis of the pancreatic islets in Sprague-Dawley rats.
Imaoka, M., Satoh, H. and Furuhama, K.
Toxicologic Pathology 35: 388-394, 2007
# Effect of 5-Campestenone (24-methylcholest-5-en-3-one) on Zucker Diabetic Fatty Rats as a Type 2 Diabetes Mellitus Model
R.Konno, Y.,Kaneko, K.,Suzuki, Y.,Matsui
Horm Metab Res ; 37(3): 79-83,2005
# Oxidized but not acetylated low-density lipoprotein reduces preproinsulin mRNA expression and secretion of insulin from HIT-T15 cells.
Okajima,F.,Kurihara,M.,Ono,C.,Nakajima,Y.,Tanimura,K.,Sugihara,H.,Ttsuguchi,A.,Nakagawa,K., Miyazawa,T.,and Oikawa,S.
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, Volume 1687, Issues 1-3, pp.173-180, 2005
# The role of calcium/calmodulin-dependent protein kinase cascade in glucose upregulation of insulin gene expression
Xiao Yu, Koji Murao, Yoshitaka Sayo, Hitomi Imachi, Wen M. Cao, Shouji Ohtsuka, Michio Niimi, Hiroshi Tokumitsu, Hiroyuki Inuzuka, Norman C.W. Wong, Ryoji Kobayashi, and Toshihiko Ishida
Diabetes, 53: 1475-1481, 2004
# PVA hydrogel sheet macroencapsulation for the bioartificial pancreas.
Qi M, Gu Y, Sakata N, Kim D, Shirouzu Y, Yamamoto C, Hiura A, Sumi S, Inoue K.
Biomaterials. 25: 5885-5892, 2004
# Alterations in vascular endothelial function in the aorta and mesenteric artery in type II diabetic rats
Takayuki Matsumoto, Kentaro Wakabayashi, Tsuneo Kobayashi, and Katsuo Kamata
Can. J. Physiol. Pharmacol. 82(3): 175-182, 2004
# Effect of eicosapentaenoic acid ethyl ester v. oleic acid-rich safflower
oil on insulin resistance in type 2 diabetic model rats with hypertriacylglycerolaemia
Asako Minami, Noriko Ishimura, Sadaichi Sakamoto, Eiko Takishita, Kazuaki Mawatari,
Kazuko Okada and Yutaka Nakaya
British J Nutrition 87, 157-162, 2002
# Evaluation of Insulin Secretion of Isolated Rat Islets Cultured in Extracellular Matrix
Nagata N.; Gu Y.; Hori H.; Balamurugan A.N.; Touma M.; Kawakami Y.; Wang W.; Baba T.T.; Satake A.; Nozawa M.; Tabata Y.; Inoue K.
Cell Transplantation, 10, 447-451, 2001
| Page top |
Rat Insulin ELISA KIT (H-type) (AKRIN-010H)
Original reports
#Regulation of oxidative stress and inflammation by hepatic adiponectin receptor 2 in an animal model of nonalcoholic steatohepatitis
Matsunami,T.,Sato,Y.,Ariga,S.,Sato,T.,Kashimura,H.,Hasegawa,Y.,Yukawa,M.
Int J Clin Exp Pathol.3(5):472-481,2010
# Additional Effect of Visceral Fat Resection in an Obese Rat Model of Gastric Banding
Endo, Y., Ohta, M., Hirashita, T., Eguchi, H., Kai, S. and Kitano, S.
Obesity Surgery, Volume 19, Number 6, 777-782
# Improvement of islet culture with sericin
Ogawa, A. et al
J. Biosci. Bioeng., 98, 217-219, 2004
# Single-Allele Correction of The Dmo1 Locus In Congenic Animals Substantially Attenuates Obesity, Dyslipidaemia And Diabetes Phenotypes Of The Oletf Rat
Watanabe T.; Okuno S.; Ono T.; Yamasaki Y.; Oga K.; Mizoguchi-Miyakita A.; Miyao H.; Suzuki M.; Momota H.; Goto Y.; Shinomiya H.; Hishigaki H.; Hayashi I.; Asai T.; Wakitani S.; Takagi T.; Nakamura Y.; Tanigami A.
Clinical and Experimental Pharmacology and Physiology, Volume 28, 28-42(15) ,2003
# Effects of Dmo1 on obesity, dyslipidaemia and hyperglycaemia in the Otsuka Long Evans Tokushima Fatty strain
Okuno、S., Watanabe、T.K., Ono, T., Oga, K., Mizoguchi-Miyakita, A., Yamasaki, Y., Goto, Y., Shinomiya, H., Momota, H., Miyao, H., Hayashi, I., Asai, T., Suzuki, M., Harada, Y., Hishigaki, H., Wakitani, S., Takagi, T., Nakamura, Y., and Tanigami, A.
Genet. Res., Camb. 77, pp. 183-190. 2001
#Regulation of oxidative stress and inflammation by hepatic adiponectin receptor 2 in an animal model of nonalcoholic steatohepatitis
Matsunami,T.,Sato,Y.,Ariga,S.,Sato,T.,Kashimura,H.,Hasegawa,Y.,Yukawa,M.
Int J Clin Exp Pathol.3(5):472-481,2010
# Additional Effect of Visceral Fat Resection in an Obese Rat Model of Gastric Banding
Endo, Y., Ohta, M., Hirashita, T., Eguchi, H., Kai, S. and Kitano, S.
Obesity Surgery, Volume 19, Number 6, 777-782
# Improvement of islet culture with sericin
Ogawa, A. et al
J. Biosci. Bioeng., 98, 217-219, 2004
# Single-Allele Correction of The Dmo1 Locus In Congenic Animals Substantially Attenuates Obesity, Dyslipidaemia And Diabetes Phenotypes Of The Oletf Rat
Watanabe T.; Okuno S.; Ono T.; Yamasaki Y.; Oga K.; Mizoguchi-Miyakita A.; Miyao H.; Suzuki M.; Momota H.; Goto Y.; Shinomiya H.; Hishigaki H.; Hayashi I.; Asai T.; Wakitani S.; Takagi T.; Nakamura Y.; Tanigami A.
Clinical and Experimental Pharmacology and Physiology, Volume 28, 28-42(15) ,2003
# Effects of Dmo1 on obesity, dyslipidaemia and hyperglycaemia in the Otsuka Long Evans Tokushima Fatty strain
Okuno、S., Watanabe、T.K., Ono, T., Oga, K., Mizoguchi-Miyakita, A., Yamasaki, Y., Goto, Y., Shinomiya, H., Momota, H., Miyao, H., Hayashi, I., Asai, T., Suzuki, M., Harada, Y., Hishigaki, H., Wakitani, S., Takagi, T., Nakamura, Y., and Tanigami, A.
Genet. Res., Camb. 77, pp. 183-190. 2001
| Page top |
Rat Insulin ELISA KIT (U-type) (AKRIN-030)
Original reports
# Antidiabetic effect of long-term supplementation with Siraitia grosvenori on the spontaneously diabetic Goto-Kakizaki rat.
Suzuki, Y.A., Tomoda, M., Murata, Y., Inui, H., Sugiura, M., and Nakano, Y.
Brit J Nutrition 97: 770-775, 2007
# MafA differentiates rat intestinal cells into insulin-producing cells.
Nomura, S., Nakamura, T., Hashimoto, T., Nishio, Y., Maegawa, H., Kudo, M., and Kashiwagi, A.
Biochem Biophys Res Commun 349: 136-143, 2006
# Transient receptor potential vanilloid subfamily 1 expression in pancreatic islet b cells modulates insulin secretion in rats.
Akiba, Y, Kato, S., Katsube, K., Nakamura,m.，Takeuchi, K., Ishii, H., and Hibi, T.
Biochem Biophys Res Commun 321: 219-225, 2004
# Isolation of a Chromosome 1 Region Affecting Blood Pressure and Vascular Disease
Traits in the Stroke-Prone Rat Model.
Kato, N., Nabika, T., Liang, Y.Q., Mashimo, T., Inomata, H., Watanabe, T., Yanai, K., Yamori, Y., Yazaki, Y., and Sasazuki, T.
Hypertension 42:1191, 2003
# Intestinal absorption of cephalexin in diabetes mellitus model rats
Watanabe, K., Terada, K., and Sato, J.
Europian J Pharmaceutical Sci 19: 91-98, 2003
# Antidiabetic effect of long-term supplementation with Siraitia grosvenori on the spontaneously diabetic Goto-Kakizaki rat.
Suzuki, Y.A., Tomoda, M., Murata, Y., Inui, H., Sugiura, M., and Nakano, Y.
Brit J Nutrition 97: 770-775, 2007
# MafA differentiates rat intestinal cells into insulin-producing cells.
Nomura, S., Nakamura, T., Hashimoto, T., Nishio, Y., Maegawa, H., Kudo, M., and Kashiwagi, A.
Biochem Biophys Res Commun 349: 136-143, 2006
# Transient receptor potential vanilloid subfamily 1 expression in pancreatic islet b cells modulates insulin secretion in rats.
Akiba, Y, Kato, S., Katsube, K., Nakamura,m.，Takeuchi, K., Ishii, H., and Hibi, T.
Biochem Biophys Res Commun 321: 219-225, 2004
# Isolation of a Chromosome 1 Region Affecting Blood Pressure and Vascular Disease
Traits in the Stroke-Prone Rat Model.
Kato, N., Nabika, T., Liang, Y.Q., Mashimo, T., Inomata, H., Watanabe, T., Yanai, K., Yamori, Y., Yazaki, Y., and Sasazuki, T.
Hypertension 42:1191, 2003
# Intestinal absorption of cephalexin in diabetes mellitus model rats
Watanabe, K., Terada, K., and Sato, J.
Europian J Pharmaceutical Sci 19: 91-98, 2003
| Page top |
Rat Insulin ELISA KIT (U-E type) (AKRIN-130)
Original reports
#Enhancement of reactive oxygen species and induction of apoptosis in streptozotocin-induced diabetic rats under hyperbaric oxygen exposure
T. Matsunami.,Y.Sato., Y. Hasegawa., S. Ariga., H. Kashimura., T. Sato., and M. Yukawa.
Int J Clin Exp Pathol. 4(3): 255-266. 2011.
#Oxidative stress and gene expression of antioxidant enzymes in the streptozotocin-induced diabetic rats under hyperbaric oxygen exposure
Matsunami,T.,Sato,Y.,Sato,T.,Ariga,S.,Shimomura,T. and Yukawa,M.
Int J Clin Exp Pathol. 3(2): 177-188.2010
#Enhancement of reactive oxygen species and induction of apoptosis in streptozotocin-induced diabetic rats under hyperbaric oxygen exposure
T. Matsunami.,Y.Sato., Y. Hasegawa., S. Ariga., H. Kashimura., T. Sato., and M. Yukawa.
Int J Clin Exp Pathol. 4(3): 255-266. 2011.
#Oxidative stress and gene expression of antioxidant enzymes in the streptozotocin-induced diabetic rats under hyperbaric oxygen exposure
Matsunami,T.,Sato,Y.,Sato,T.,Ariga,S.,Shimomura,T. and Yukawa,M.
Int J Clin Exp Pathol. 3(2): 177-188.2010
| Page top |
Mouse Insulin ELISA KIT (AKRIN-011)
Original reports
# Antioxidative Effects of a New Lychee Fruit-Derived Polyphenol Mixture, Oligonol,
Converted into a Low-Molecular Form in Adipocytes
Sakurai, T., Nishioka, H., Fujii, H., Nakano, N., Kizai, T., Radak, Z., Izawa, T.,
Haga, S. and Ohno, H.
Bioscience, Biotechnology, and Biochemistry, Vol. 72, No.2 pp.463-476, 2008
# Citrin/mitochondrial glycerol-3-phosphate dehydrogenase double knockout mice recapitulate features of human citrin deficiency.
Saheki, T., Iijima, M., Li, M.X., Kobayashi, K., Horiuchi, M., Ushikai, M., Okumura, F., Meng, X.J., Inoue, I., Tajima, A., Moriyama, M.,Eto,K.,Kadowaki,T., Sinasac, D.S., Tsui, L.C., Tsuji, M., Okano, A., and Kobayashi, T.
J Biol Chem 282: 25041-25052, 2007
# Disruption of CXC Motif Chemokine Ligand-14 in Mice Ameliorates Obesity-induced Insulin
Resistance
Nara, N., Nakayama, Y., Okamoto, S., Tamura, H., Kiyono, M., Muraoka, M., Tanaka, K.,
Taya, C., Shitara, H., Ishii, R., Yonekawa, H., Minokoshi, Y. and Hara, T.
The Journal of Biological Chemistry, Vov. 282, Issue 42, 30794-30803, 2007
# Genetically modified rice seeds accumulating GLP-1 analogue simulate insulin secretion from a mouse pancreatic b cell line.
Sugita, K., Endo-Kasahara, S., Tada, Y., Lijun, Y., Yasuda, H., Hayashi, Y., Jomori, T., Ebinuma, H., and Takaiwa, F.
FEBS Letters 579: 1085-1088, 2005
# Increase in the Deposition of Aggregated Protein in the Glomeruli of Spontaneously
Diabetic Mice
Nagamatsu, T., Hirasawa, Y., Matsui, Y., Ohtsu, S., Yamane, K., Toyoshi, T.,
Kyuki, K. and Suzuki, Y.
Journal of Pharmacological sciences, Vol. 99, No.3 pp.287-293, 2005
# Pancreatic epithelial cells can be converted into insulin-producing cells by GLP-1 in conjunction with virus-mediated gene transfer of pdx-1.
Koizumi, M., Doi, R., Fujimoto, K., Ito, D., Toyoda, E., Mori, T., Kami, K., Kawaguchi, Y., Gittes, G., and Imamura, M.
Surgery 138: 125-133, 2005
# Hepatic regeneration and enforced PDX-1 expression accelerated transdifferentiation in liver.
Koizumi, M., Doi, R., Toyoda, E., Tulachan, S., Kami. K., Mori, T., Ito, D., Kawaguchi, Y., Fujimoto, K., Gittes, G.K., and Imamura, M.
Surgery 136: 449-457, 2004
# Mechanism of Amelioration of Insulin Resistance by {beta}-3-Adrenoceptor Agonist
AJ-9677 in the KK-Ay/Ta Diabetic Obese Mouse Model
Kato, H., Ohue, M., Kato, K., Nomura, A., Toyosawa, K., Furutani, Y., Kimura, S., and Kadowaki, T.
Diabetes 50:113-122, 2001
# Antioxidative Effects of a New Lychee Fruit-Derived Polyphenol Mixture, Oligonol,
Converted into a Low-Molecular Form in Adipocytes
Sakurai, T., Nishioka, H., Fujii, H., Nakano, N., Kizai, T., Radak, Z., Izawa, T.,
Haga, S. and Ohno, H.
Bioscience, Biotechnology, and Biochemistry, Vol. 72, No.2 pp.463-476, 2008
# Citrin/mitochondrial glycerol-3-phosphate dehydrogenase double knockout mice recapitulate features of human citrin deficiency.
Saheki, T., Iijima, M., Li, M.X., Kobayashi, K., Horiuchi, M., Ushikai, M., Okumura, F., Meng, X.J., Inoue, I., Tajima, A., Moriyama, M.,Eto,K.,Kadowaki,T., Sinasac, D.S., Tsui, L.C., Tsuji, M., Okano, A., and Kobayashi, T.
J Biol Chem 282: 25041-25052, 2007
# Disruption of CXC Motif Chemokine Ligand-14 in Mice Ameliorates Obesity-induced Insulin
Resistance
Nara, N., Nakayama, Y., Okamoto, S., Tamura, H., Kiyono, M., Muraoka, M., Tanaka, K.,
Taya, C., Shitara, H., Ishii, R., Yonekawa, H., Minokoshi, Y. and Hara, T.
The Journal of Biological Chemistry, Vov. 282, Issue 42, 30794-30803, 2007
# Genetically modified rice seeds accumulating GLP-1 analogue simulate insulin secretion from a mouse pancreatic b cell line.
Sugita, K., Endo-Kasahara, S., Tada, Y., Lijun, Y., Yasuda, H., Hayashi, Y., Jomori, T., Ebinuma, H., and Takaiwa, F.
FEBS Letters 579: 1085-1088, 2005
# Increase in the Deposition of Aggregated Protein in the Glomeruli of Spontaneously
Diabetic Mice
Nagamatsu, T., Hirasawa, Y., Matsui, Y., Ohtsu, S., Yamane, K., Toyoshi, T.,
Kyuki, K. and Suzuki, Y.
Journal of Pharmacological sciences, Vol. 99, No.3 pp.287-293, 2005
# Pancreatic epithelial cells can be converted into insulin-producing cells by GLP-1 in conjunction with virus-mediated gene transfer of pdx-1.
Koizumi, M., Doi, R., Fujimoto, K., Ito, D., Toyoda, E., Mori, T., Kami, K., Kawaguchi, Y., Gittes, G., and Imamura, M.
Surgery 138: 125-133, 2005
# Hepatic regeneration and enforced PDX-1 expression accelerated transdifferentiation in liver.
Koizumi, M., Doi, R., Toyoda, E., Tulachan, S., Kami. K., Mori, T., Ito, D., Kawaguchi, Y., Fujimoto, K., Gittes, G.K., and Imamura, M.
Surgery 136: 449-457, 2004
# Mechanism of Amelioration of Insulin Resistance by {beta}-3-Adrenoceptor Agonist
AJ-9677 in the KK-Ay/Ta Diabetic Obese Mouse Model
Kato, H., Ohue, M., Kato, K., Nomura, A., Toyosawa, K., Furutani, Y., Kimura, S., and Kadowaki, T.
Diabetes 50:113-122, 2001
| Page top |
Mouse Insulin ELISA KIT (TMB) (AKRIN-011T)
Original reports
#Endoplasmic Reticulum Stress Inhibits STAT3-Dependent Suppression of Hepatic Gluconeogenesis via Dephosphprylation and Deacetylation
K. Kimura., T. Yamada., M. Matsumoto., Y. Kido., T. Hosooka., S. Asahara., T. Matsuda., T. Ota., H. Watanabe., Y. Sai., K. Miyamoto., S. Kaneko., M. Kasuga., H. Inoue.
Diabetes Vol. 61 No.1,61-73, 2012
#A novel dipeptidyl peptidase IV inhibitor DA-1229 ameliorates streptozotocin-induced diabetes by increasing b-cell replication and neogenesis
J, M, Cho., H, W, Jang., H, Cheon.,Y, T, Jeong., D-H, Kim., Y-M, Lim., S, Choi., E, Yang., C-Y, Shin., M, H, Son., S, H, Kim., H, Kim., M, Lee.
Diabetes Research and Clinical Practice.Vol. 91, Issue 1, 2011, Pages 72-79
#The Murine Glucagon-Like Peptide-1 Receptor Is Essential for Control of Bone Resorption
C, Yamada., Y, Yamada., K, Tsukiyama., K, Yamada., N, Udagawa., N, Takahashi., K, Tanaka., D, J, Drucker., Y, Seino., and N, Inagaki
Endocrinology. 2008 Vol. 149 no. 2 574-579
#Usefulness of colon targeted DHA and EPA as novel diabetes medications that promote intrinsic GLP-1 secretion
M, Morishita., T, Tanaka., T, Shida., K, Takayama.
Journal of Controlled Release.Vol. 132, Issue 2, 2008, Pages 99-104
#Free fatty acids administered into the colon promote the secretion of glucagon-like peptide-1 and insulin
T, Adachi., T, Tanaka., K, Takemoto., T, Koshimizu., A, Hirasawa., G, Tsujimoto.
Biochemical and Biophysical Research Communications.Vol. 340, Issue 1, 2006, Pages 332-337
#Pancreatic epithelial cells can be converted into insulin-producing cells by GLP-1 in conjunction with virus-mediated gene transfer of pdx-1
M, Koizumi., R, Doi., K, Fujimoto., D, Ito., E, Toyoda., T, Mori., K, Kami.,Y, Kawaguchi., G, K, Gittes., M, Imamura.
Surgery.Vol.138, Issue 2, 2005, Pages 125-133
#Glucagon-like peptide 1 (1?37) converts intestinal epithelial cells into insulin-producing cells
A, Suzuki., H, Nakauchi., and H, Taniguchi.
PNAS April 29,2003. Vol.100 No.9,5034-5039
#Dietary protein deprivation upregulates insulin signaling and inhibits gluconeogenesis in rat liver
Y. Toyoshima., R. Tokita., Y. Ohne., F. Hakuno., T. Noguchi., S. Minami., H. Kato., and S. Takahashi.
Journal of Molecular Endocrinology.47(1).2011
#Sorting nexin 19 regulates the number of dense core vesicles in pancreatic b-cells
S. Harashima., T. Horiuchi., Y. Wang., A. L. Notkins., Y. Seino., N. Inagaki.
Journal of Diabetes Investigation.published online: 28 JUN 2011
#Synergistic improvement in insulin resistance with a combination of fenofibrate and rosiglitazone in obese type 2 diabetic mice
W.S.Choi., J.J.Lee., Y. Kim., I.S. Kim., W.Y. Zhang., and C.S. Myung.
Archives of Pharmacal Research .Vol.34(4),615-624,2011
#Preventive Effect of Boiogito on Metabolic Disorders in the TSOD Mouse, a Model of Spontaneous Obese Type II Diabetes Mellitus
T. Shimada., T. Akase., M. Kosugi., and M. Aburada.
Evidence-Based Complementary and Alternative Medicine.Volume 2011.
#Preventive Effect of Pine Bark Extract (Flavangenol) on Metabolic Disease in Western Diet-Loaded Tsumura Suzuki Obese Diabetes Mice
T. Shimada., M. Kosugi., D. Tokuhara., M. Tsubata., T. Kamiya., M. Sameshima., R. Nagamine., K. Takagaki., K. Miyamoto., and M. Aburada.
Evidence-Based Complementary and Alternative Medicine.Volume 2011.
#Preventive Effects of Salacia reticulata on Obesity and Metabolic Disorders in TSOD Mice
T. Akase., T. Shimada., Y. Harasawa., T. Akase., Y. Ikeya., E. Nagai., S.Iizuka., G. Nakagami., S. Iizaka., H. Sanada.,and M. Aburada.
Evidence-Based Complementary and Alternative Medicine.Volume 2011.
#Anti-Obesity and Anti-Diabetic Effects of Acacia Polyphenol in Obese Diabetic KKAy Mice Fed High-Fat Diet
N. Ikarashi., T. Toda., T. Okaniwa., K. Ito., W.Ochiai., and K. Sugiyama.
Evidence-Based Complementary and Alternative Medicine.Volume 2011.
#Preventive effects of Salacia reticulata on non-alcoholic fatty liver disease (NAFLD)/ non-alcoholic steatohepatitis (NASH) in monosodium glutamate treated mice
M. Watanabe., T. Shimada., S. Iiduka., N. Iida., K. Kojima., J. Ishizaki., Y. Sai., K. Miyamoto., and M. Aburada.
Journal of Traditional Medicines .Vol. 28 (2011) , No. 2 pp.73-82
#Effects of antidiabetic drugs in high-fat diet and streptozotocin-nicotinamide-induced type 2 diabetic mice
A. Tahara., A. Matsuyama-Yokono., and M. Shibasaki.
European Journal of Pharmacology.Vol.655, Issues 1-3, 108-116. 2011.
#Preventive Effects of (-)-Epigallocatechin Gallate on Diethylnitrosamine-Induced Liver Tumorigenesis in Obese and Diabetic C57BL/KsJ-db/db Mice
M. Shimizu., H.Sakai, Y.Shirakami., Y.Yasuda., M.Kubota., D.Terakura., A. Baba., T.Ohno., Y.Hara., T. Tanaka., and H. Moriwaki.
Cancer Prev Res; 4(3); 396?403. 2011 AACR
#Dietary Aloe Improves Insulin Sensitivity via the Suppression of Obesity-induced Inflammation in Obese Mice
E. Shin., K.S.Shim., H. Kong., S.Lee., S. Shin., J. Kwon., T.H.Jo., Y-I. Park., C-K. Lee., and K. Kim.
Immune Network.Vol.11(1),59-67.2011
#Expression of CD38 with intracellular enzymatic activity: a possible explanation for the insulin release induced by intracellular cADPR
Y. Ohta., A. Kitanaka., K. Mihara., O. Imataki., H. Ohnishi., T. Tanaka., T. Taminato., and Y. Kubota.
Molecular and Cellular Biochemistry .Vol.352, Numbers 1-2, 293-299.2011
#Insulin receptor mutation results in insulin resistance and hyperinsulinemia but does not exacerbate Alzheimer’s-like phenotypes in mice
K. Murakami., S. Yokoyama., N. Murata., Y. Ozawa., K. Irie., T. Shirasawa., and T. Shimizu.
Biochemical and Biophysical Research Communications.Vol.409(1),34-39.2011
#Enhanced insulin secretion and sensitization in diabetic mice on chronic treatment with a transient receptor potential vanilloid 1 antagonist
H. Tanaka., A. Shimaya., T. Kiso., T. Kuramochi., T. Shimokawa., and M. Shibasaki.
Life Sciences.Vol.88, Issues 11-12,559-563. 2011.
#Voltage-gated K+ channel KCNQ1 regulates insulin secretion in MIN6 b-cell line
K. Yamagata., T. Senokuchi., M. Lub., M. Takemoto., M.D. F. Karim., C. Go., Y. Sato., M. Hatta., T. Yoshizawa., E. Araki., J. Miyazaki. and W-J. Song.
Biochemical and Biophysical Research Communications.Vol.407(3),620-625. 2011.
#Beneficial effect of oral administration of Lactobacillus casei strain Shirota on insulin resistance in diet-induced obesity mice
E. Naito., Y. Yoshida., K. Makino., Y. Kounoshi., S. Kunihiro., R. Takahashi., T. Matsuzaki., K. Miyazaki., F. Ishikawa.
Journal of Applied Microbiology.Vol.110(3),650-657.2011
#Antiobesity effects of Bifidobacterium breve strain B-3 supplementation in a mouse model with high-fat diet-induced obesity.
S. Kondo., J.Z. Xiao., T. Satoh., T. Odamaki., S. Takahashi., H. Sugahara., T. Yaeshima., K. Iwatsuki., A. Kamei., K. Abe.
Biosci Biotechnol Biochem. 2010;74(8):1656-61.
# Dose dependent development of diabetes mellitus and non-alcoholic steatohepatitis in monosodium glutamate-induced obese mice
Sasaki,Y.,Suzuki,W.,Shimada,T.,Iizuka,S.,Nakamura,S.,Nagata,M.,Fujimoto,M.,
Tsuneyama,K.,Hokao,R.,Miyamoto,K.,Aburada,M.
Life Sciences 85,490-498,2009
# Preventive Effect of Boiogito on Metabolic Disorders in the TSOD Mouse, a Model of Spontaneous Obese Type II Diabetes Mellitus.
Shimada, T., Akase, T., Kosugi, M., and Aburada, M.
eCAM Advance Access, pp1-8, 2009
#Transgenic expression of a mutated cyclin-dependent kinase 4(CDK4/R24G)
in pancreatic β-cells prevents progression of diabetes in db/db mice
Miyawaki,K.,Inoue,H.,Keshavarz,P.,Mizuta,K.,Sato,A.,Sakamoto,Y.,Moritani,M.,
Kunika,K.,Tanahashi,T.and Itakura,M.
Diabetes Research and Clinical Practice 82,33-41,2008
# Abdominal Irradiation Ameliorates Obesity in ob/ob Mice
Okada, S., Kobayashi, K., Ishikawa, M., Inoue, N., Yamada, N. and Shimano, H.
J Clin Biochem Nutr.; 40(2): 123-130,2007 March
# Agent for Preventing Metabolic Syndrome .
Okada,Y., and Iio, K.
US Patent App. 11/567, 038, 2006
# Differentiation of embryonic stem cells into insulin-producing cells promoted by Nkx2.2 gene transfer
Shiroi, A., Ueda, S., Ouji, Y., Saito, K., Moriya, K., Sugie, Y., Fukui, H., Ishizaka, S., Yoshikawa, M.
World J Gastroenterol 11(27): 4161-4166, 2005
# PKClregulates glucose-induced insulin secretion through modulation of gene expression in pancreatic ß cells
Hashimoto, N., Kido, Y., Uchida, T., Matsuda, T., Suzuki, K., Inoue, H., Matsumoto, M., Ogawa, W., Maeda, S., Fujihara, H., Ueta, Y., Uchiyama, Y., Akimoto, K., Ohno, S., Noda, T., and Kasuga, M.
J. Clin. Invest. 115:138-145 (2005).
# Increased oxidative stress in obesity and its impact on metabolic syndrome
Furukawa, S., Fujita, T., Shimabukuro, M., Iwaki, M., Yamada, Y., Nakajima, Y., Nakayama, O., Makishima, M., Matsuda, M., and Shimomura, I.
J. Clin. Invest. 114:1752-1761, 2004
# A Novel Selective Peroxisome Proliferator-Activated Receptor Agonist,
2-Methyl-c-5-[4-[5-methyl-2-(4-methylphenyl)-4-oxazolyl]butyl]-1,3-dioxane-r-2-carboxylic
acid (NS-220), Potently Decreases Plasma Triglyceride and Glucose Levels and Modifies Lipoprotein Profiles in KK-Ay Mice
Kuwabara, K., Murakami, K., Todo, M., Aoki, T., Asaki, T., Murai, M., and Yano, J.
J Pharmacol Exp Therapeutics 309: 970-977, 2004
# A series of maturity onset diabetes of the young, type 2 (MODY2) mouse models generated by a large-scale ENU mutagenesis program
Inoue, M., Sakuraba, Y., Motegi, H., Kubota, N., Toki, H., Matsui, J., Toyoda, Y., Miwa, I., Terauchi, Y., Kadowaki, T., Shigeyama, Y., Kasuga, M., Adachi, T., Fujimoto, N., Matsumoto, R., Tsuchihashi, K., Kagami, T., Inoue, A., Kaneda, H., Ishijima, J., Masuya, H., Suzuki, T., Wakana, S., Gondo, Y., Minowa, O., Shiroishi, T., and Noda, T.
Human Molecular Genetics 13:1147-1157, 2004
# Insulin/Foxo1 Pathway Regulates Expression Levels of Adiponectin Receptors and Adiponectin Sensitivity*
Tsuchida, A., Yamauchi, T., Ito, Y., Hada, Y., Maki, T., Takekawa, S., Kamon, J., Kobayashi, M., Suzuki, R., Hara, K., Kubota,N., Terauchi, Y., Froguel, P., Nakae, J., Kasuga, M., Accili, D., Tobe, K., Ueki, K., Nagai, R., and Kadowaki, T.
J. Biol. Chem., Vol. 279, Issue 29, 30817-30822, 2004
# Identification of Insulin-Producing Cells Derived from Embryonic Stem Cells by Zinc-Chelating Dithizone
Shiroi, A., Yoshikawa, M., Yokota, H., Fukui, H., Ishizaka, S., Tatsumi, K., and Takahashi, Y.
Stem Cells 20 :284-292, 2002
# Susceptibility and Negative Epistatic Loci Contributing to Type 2 Diabetes and Related Phenotypes in a KK/Ta Mouse Model
Shike, T., Hirose, S., Kobayashi, M., Funabiki, K., Shirai, T., and Tomino, Y.
Diabetes 50:1943-1948, 2001
Presentations at scientific meetings
#Significance of Circulating Ghrelin (Active and Inactive) in the Progression of
Renal Injury in Diabetes Mellitus and In Non-Smooth Muscle Calponin (Calponin-h2) Transgenic Mice
41st Annual Meeting & Scientific Exposition November 4 - 9, 2008
Pennsylvania Convention Center Philadelphia, Pennsylvania
#Endoplasmic Reticulum Stress Inhibits STAT3-Dependent Suppression of Hepatic Gluconeogenesis via Dephosphprylation and Deacetylation
K. Kimura., T. Yamada., M. Matsumoto., Y. Kido., T. Hosooka., S. Asahara., T. Matsuda., T. Ota., H. Watanabe., Y. Sai., K. Miyamoto., S. Kaneko., M. Kasuga., H. Inoue.
Diabetes Vol. 61 No.1,61-73, 2012
#A novel dipeptidyl peptidase IV inhibitor DA-1229 ameliorates streptozotocin-induced diabetes by increasing b-cell replication and neogenesis
J, M, Cho., H, W, Jang., H, Cheon.,Y, T, Jeong., D-H, Kim., Y-M, Lim., S, Choi., E, Yang., C-Y, Shin., M, H, Son., S, H, Kim., H, Kim., M, Lee.
Diabetes Research and Clinical Practice.Vol. 91, Issue 1, 2011, Pages 72-79
#The Murine Glucagon-Like Peptide-1 Receptor Is Essential for Control of Bone Resorption
C, Yamada., Y, Yamada., K, Tsukiyama., K, Yamada., N, Udagawa., N, Takahashi., K, Tanaka., D, J, Drucker., Y, Seino., and N, Inagaki
Endocrinology. 2008 Vol. 149 no. 2 574-579
#Usefulness of colon targeted DHA and EPA as novel diabetes medications that promote intrinsic GLP-1 secretion
M, Morishita., T, Tanaka., T, Shida., K, Takayama.
Journal of Controlled Release.Vol. 132, Issue 2, 2008, Pages 99-104
#Free fatty acids administered into the colon promote the secretion of glucagon-like peptide-1 and insulin
T, Adachi., T, Tanaka., K, Takemoto., T, Koshimizu., A, Hirasawa., G, Tsujimoto.
Biochemical and Biophysical Research Communications.Vol. 340, Issue 1, 2006, Pages 332-337
#Pancreatic epithelial cells can be converted into insulin-producing cells by GLP-1 in conjunction with virus-mediated gene transfer of pdx-1
M, Koizumi., R, Doi., K, Fujimoto., D, Ito., E, Toyoda., T, Mori., K, Kami.,Y, Kawaguchi., G, K, Gittes., M, Imamura.
Surgery.Vol.138, Issue 2, 2005, Pages 125-133
#Glucagon-like peptide 1 (1?37) converts intestinal epithelial cells into insulin-producing cells
A, Suzuki., H, Nakauchi., and H, Taniguchi.
PNAS April 29,2003. Vol.100 No.9,5034-5039
#Dietary protein deprivation upregulates insulin signaling and inhibits gluconeogenesis in rat liver
Y. Toyoshima., R. Tokita., Y. Ohne., F. Hakuno., T. Noguchi., S. Minami., H. Kato., and S. Takahashi.
Journal of Molecular Endocrinology.47(1).2011
#Sorting nexin 19 regulates the number of dense core vesicles in pancreatic b-cells
S. Harashima., T. Horiuchi., Y. Wang., A. L. Notkins., Y. Seino., N. Inagaki.
Journal of Diabetes Investigation.published online: 28 JUN 2011
#Synergistic improvement in insulin resistance with a combination of fenofibrate and rosiglitazone in obese type 2 diabetic mice
W.S.Choi., J.J.Lee., Y. Kim., I.S. Kim., W.Y. Zhang., and C.S. Myung.
Archives of Pharmacal Research .Vol.34(4),615-624,2011
#Preventive Effect of Boiogito on Metabolic Disorders in the TSOD Mouse, a Model of Spontaneous Obese Type II Diabetes Mellitus
T. Shimada., T. Akase., M. Kosugi., and M. Aburada.
Evidence-Based Complementary and Alternative Medicine.Volume 2011.
#Preventive Effect of Pine Bark Extract (Flavangenol) on Metabolic Disease in Western Diet-Loaded Tsumura Suzuki Obese Diabetes Mice
T. Shimada., M. Kosugi., D. Tokuhara., M. Tsubata., T. Kamiya., M. Sameshima., R. Nagamine., K. Takagaki., K. Miyamoto., and M. Aburada.
Evidence-Based Complementary and Alternative Medicine.Volume 2011.
#Preventive Effects of Salacia reticulata on Obesity and Metabolic Disorders in TSOD Mice
T. Akase., T. Shimada., Y. Harasawa., T. Akase., Y. Ikeya., E. Nagai., S.Iizuka., G. Nakagami., S. Iizaka., H. Sanada.,and M. Aburada.
Evidence-Based Complementary and Alternative Medicine.Volume 2011.
#Anti-Obesity and Anti-Diabetic Effects of Acacia Polyphenol in Obese Diabetic KKAy Mice Fed High-Fat Diet
N. Ikarashi., T. Toda., T. Okaniwa., K. Ito., W.Ochiai., and K. Sugiyama.
Evidence-Based Complementary and Alternative Medicine.Volume 2011.
#Preventive effects of Salacia reticulata on non-alcoholic fatty liver disease (NAFLD)/ non-alcoholic steatohepatitis (NASH) in monosodium glutamate treated mice
M. Watanabe., T. Shimada., S. Iiduka., N. Iida., K. Kojima., J. Ishizaki., Y. Sai., K. Miyamoto., and M. Aburada.
Journal of Traditional Medicines .Vol. 28 (2011) , No. 2 pp.73-82
#Effects of antidiabetic drugs in high-fat diet and streptozotocin-nicotinamide-induced type 2 diabetic mice
A. Tahara., A. Matsuyama-Yokono., and M. Shibasaki.
European Journal of Pharmacology.Vol.655, Issues 1-3, 108-116. 2011.
#Preventive Effects of (-)-Epigallocatechin Gallate on Diethylnitrosamine-Induced Liver Tumorigenesis in Obese and Diabetic C57BL/KsJ-db/db Mice
M. Shimizu., H.Sakai, Y.Shirakami., Y.Yasuda., M.Kubota., D.Terakura., A. Baba., T.Ohno., Y.Hara., T. Tanaka., and H. Moriwaki.
Cancer Prev Res; 4(3); 396?403. 2011 AACR
#Dietary Aloe Improves Insulin Sensitivity via the Suppression of Obesity-induced Inflammation in Obese Mice
E. Shin., K.S.Shim., H. Kong., S.Lee., S. Shin., J. Kwon., T.H.Jo., Y-I. Park., C-K. Lee., and K. Kim.
Immune Network.Vol.11(1),59-67.2011
#Expression of CD38 with intracellular enzymatic activity: a possible explanation for the insulin release induced by intracellular cADPR
Y. Ohta., A. Kitanaka., K. Mihara., O. Imataki., H. Ohnishi., T. Tanaka., T. Taminato., and Y. Kubota.
Molecular and Cellular Biochemistry .Vol.352, Numbers 1-2, 293-299.2011
#Insulin receptor mutation results in insulin resistance and hyperinsulinemia but does not exacerbate Alzheimer’s-like phenotypes in mice
K. Murakami., S. Yokoyama., N. Murata., Y. Ozawa., K. Irie., T. Shirasawa., and T. Shimizu.
Biochemical and Biophysical Research Communications.Vol.409(1),34-39.2011
#Enhanced insulin secretion and sensitization in diabetic mice on chronic treatment with a transient receptor potential vanilloid 1 antagonist
H. Tanaka., A. Shimaya., T. Kiso., T. Kuramochi., T. Shimokawa., and M. Shibasaki.
Life Sciences.Vol.88, Issues 11-12,559-563. 2011.
#Voltage-gated K+ channel KCNQ1 regulates insulin secretion in MIN6 b-cell line
K. Yamagata., T. Senokuchi., M. Lub., M. Takemoto., M.D. F. Karim., C. Go., Y. Sato., M. Hatta., T. Yoshizawa., E. Araki., J. Miyazaki. and W-J. Song.
Biochemical and Biophysical Research Communications.Vol.407(3),620-625. 2011.
#Beneficial effect of oral administration of Lactobacillus casei strain Shirota on insulin resistance in diet-induced obesity mice
E. Naito., Y. Yoshida., K. Makino., Y. Kounoshi., S. Kunihiro., R. Takahashi., T. Matsuzaki., K. Miyazaki., F. Ishikawa.
Journal of Applied Microbiology.Vol.110(3),650-657.2011
#Antiobesity effects of Bifidobacterium breve strain B-3 supplementation in a mouse model with high-fat diet-induced obesity.
S. Kondo., J.Z. Xiao., T. Satoh., T. Odamaki., S. Takahashi., H. Sugahara., T. Yaeshima., K. Iwatsuki., A. Kamei., K. Abe.
Biosci Biotechnol Biochem. 2010;74(8):1656-61.
# Dose dependent development of diabetes mellitus and non-alcoholic steatohepatitis in monosodium glutamate-induced obese mice
Sasaki,Y.,Suzuki,W.,Shimada,T.,Iizuka,S.,Nakamura,S.,Nagata,M.,Fujimoto,M.,
Tsuneyama,K.,Hokao,R.,Miyamoto,K.,Aburada,M.
Life Sciences 85,490-498,2009
# Preventive Effect of Boiogito on Metabolic Disorders in the TSOD Mouse, a Model of Spontaneous Obese Type II Diabetes Mellitus.
Shimada, T., Akase, T., Kosugi, M., and Aburada, M.
eCAM Advance Access, pp1-8, 2009
#Transgenic expression of a mutated cyclin-dependent kinase 4(CDK4/R24G)
in pancreatic β-cells prevents progression of diabetes in db/db mice
Miyawaki,K.,Inoue,H.,Keshavarz,P.,Mizuta,K.,Sato,A.,Sakamoto,Y.,Moritani,M.,
Kunika,K.,Tanahashi,T.and Itakura,M.
Diabetes Research and Clinical Practice 82,33-41,2008
# Abdominal Irradiation Ameliorates Obesity in ob/ob Mice
Okada, S., Kobayashi, K., Ishikawa, M., Inoue, N., Yamada, N. and Shimano, H.
J Clin Biochem Nutr.; 40(2): 123-130,2007 March
# Agent for Preventing Metabolic Syndrome .
Okada,Y., and Iio, K.
US Patent App. 11/567, 038, 2006
# Differentiation of embryonic stem cells into insulin-producing cells promoted by Nkx2.2 gene transfer
Shiroi, A., Ueda, S., Ouji, Y., Saito, K., Moriya, K., Sugie, Y., Fukui, H., Ishizaka, S., Yoshikawa, M.
World J Gastroenterol 11(27): 4161-4166, 2005
# PKClregulates glucose-induced insulin secretion through modulation of gene expression in pancreatic ß cells
Hashimoto, N., Kido, Y., Uchida, T., Matsuda, T., Suzuki, K., Inoue, H., Matsumoto, M., Ogawa, W., Maeda, S., Fujihara, H., Ueta, Y., Uchiyama, Y., Akimoto, K., Ohno, S., Noda, T., and Kasuga, M.
J. Clin. Invest. 115:138-145 (2005).
# Increased oxidative stress in obesity and its impact on metabolic syndrome
Furukawa, S., Fujita, T., Shimabukuro, M., Iwaki, M., Yamada, Y., Nakajima, Y., Nakayama, O., Makishima, M., Matsuda, M., and Shimomura, I.
J. Clin. Invest. 114:1752-1761, 2004
# A Novel Selective Peroxisome Proliferator-Activated Receptor Agonist,
2-Methyl-c-5-[4-[5-methyl-2-(4-methylphenyl)-4-oxazolyl]butyl]-1,3-dioxane-r-2-carboxylic
acid (NS-220), Potently Decreases Plasma Triglyceride and Glucose Levels and Modifies Lipoprotein Profiles in KK-Ay Mice
Kuwabara, K., Murakami, K., Todo, M., Aoki, T., Asaki, T., Murai, M., and Yano, J.
J Pharmacol Exp Therapeutics 309: 970-977, 2004
# A series of maturity onset diabetes of the young, type 2 (MODY2) mouse models generated by a large-scale ENU mutagenesis program
Inoue, M., Sakuraba, Y., Motegi, H., Kubota, N., Toki, H., Matsui, J., Toyoda, Y., Miwa, I., Terauchi, Y., Kadowaki, T., Shigeyama, Y., Kasuga, M., Adachi, T., Fujimoto, N., Matsumoto, R., Tsuchihashi, K., Kagami, T., Inoue, A., Kaneda, H., Ishijima, J., Masuya, H., Suzuki, T., Wakana, S., Gondo, Y., Minowa, O., Shiroishi, T., and Noda, T.
Human Molecular Genetics 13:1147-1157, 2004
# Insulin/Foxo1 Pathway Regulates Expression Levels of Adiponectin Receptors and Adiponectin Sensitivity*
Tsuchida, A., Yamauchi, T., Ito, Y., Hada, Y., Maki, T., Takekawa, S., Kamon, J., Kobayashi, M., Suzuki, R., Hara, K., Kubota,N., Terauchi, Y., Froguel, P., Nakae, J., Kasuga, M., Accili, D., Tobe, K., Ueki, K., Nagai, R., and Kadowaki, T.
J. Biol. Chem., Vol. 279, Issue 29, 30817-30822, 2004
# Identification of Insulin-Producing Cells Derived from Embryonic Stem Cells by Zinc-Chelating Dithizone
Shiroi, A., Yoshikawa, M., Yokota, H., Fukui, H., Ishizaka, S., Tatsumi, K., and Takahashi, Y.
Stem Cells 20 :284-292, 2002
# Susceptibility and Negative Epistatic Loci Contributing to Type 2 Diabetes and Related Phenotypes in a KK/Ta Mouse Model
Shike, T., Hirose, S., Kobayashi, M., Funabiki, K., Shirai, T., and Tomino, Y.
Diabetes 50:1943-1948, 2001
Presentations at scientific meetings
#Significance of Circulating Ghrelin (Active and Inactive) in the Progression of
Renal Injury in Diabetes Mellitus and In Non-Smooth Muscle Calponin (Calponin-h2) Transgenic Mice
41st Annual Meeting & Scientific Exposition November 4 - 9, 2008
Pennsylvania Convention Center Philadelphia, Pennsylvania
| Page top |
Mouse Insulin ELISA KIT (H-type) (AKRIN-011H)
Original reports
#Cell coupling regulates Ins1, Pdx-1 and MafA to promote insulin secretion in mouse pancreatic beta cells
K.C. Yang., Z. Qi., G. Yanai., Y. Shirouza., D.H. Lu., H.S. Lee., and S. Sumi.
Process Biochemistry.Article in Press
#Cell coupling regulates Ins1, Pdx-1 and MafA to promote insulin secretion in mouse pancreatic beta cells
K.C. Yang., Z. Qi., G. Yanai., Y. Shirouza., D.H. Lu., H.S. Lee., and S. Sumi.
Process Biochemistry.Article in Press
| Page top |
Mouse Insulin ELISA KIT (U-type) (AKRIN-031)
Original reports
#LOSS OF GRANUPHILIN AND OF SYNTAXIN-1A CAUSE DIFFERENTIAL EFFECTS ON INSULIN GRANULE DOCKING AND FUSION
H. Wang., R. Ishizaki., E. Kobayashi., T. Fujiwara., K. Akagawa., and T.Izumi1.
The Journal of Biological Chemistry.286(31).2011
#Rapid Rehydration and Moderate Plasma Glucose Elevation by Fluid Containing Enzymatically Synthesized Glycogen
K. Inagaki., K. Ishihara., M. Ishida., A. Watanabe., M. Fujiwara., Y. Komatsu., M. Shirai., Y. Kato., A. Takanezawa., T. Furuwashiki., H. Takata., and Y. Seyama.
Journal of Nutritional Science and Vitaminology.Vol. 57 (2011) , No. 2 pp.170-176
#Dynamic modification of sphingomyelin in lipid microdomains controls development of obesity, fatty liver, and type 2 diabetes
S. Mitsutake., K. Zama., H. Yokota.,T. Yoshida., M. Tanaka., M. Mitsui., M. Ikawa., M. Okabe., Y. Tanaka., T. Yamashita., H. Takemoto., T. Okazaki., K. Watanabe., and Y. Igarashi.
The Journal of Biological Chemistry.286(31).2011
# PPARaactivation is essential for HCV core protein-induced hepatic steatosis and hepatocellular carcinoma in mice.
Tanaka, N., Moriya, K., Kiyosawa, K., Koike, K., Gonzalez, F.J. and Aoyama, T.
J Clin Invest 118: 683-694, 2008
#Transgenic expression of a mutated cyclin-dependent kinase 4(CDK4/R24G)
in pancreatic β-cells prevents progression of diabetes in db/db mice
Miyawaki,K.,Inoue,H.,Keshavarz,P.,Mizuta,K.,Sato,A.,Sakamoto,Y.,Moritani,M.,
Kunika,K.,Tanahashi,T.and Itakura,M.
Diabetes Research and Clinical Practice 82,33-41,2008
# Hypoglycemic effects of exopolysaccharides produced by mycelial cultures of two different mushrooms Tremella fuciformis and Phellinus baumii in ob/ob mice.
Cho, E.J., Hwang, H.J., Kim, S.W., Oh , J.Y., Baek, Y.M., Choi, J.W., Bae, S.H., and Yun, J.W.
Applied Microbiol Biotechnol , 75: 1257-1265, 2007
# Schnurri-2 controls BMP-dependent adipogenesis via interaction with Smad proteins.
Jin, W., Takagi, T., Kanesashi, S., Kurahashi, T., Nomura, T., Harade, J., and Ishii, S.
Developmental Cell, 10: 461-471, 2006
# Chromosome 2 locus Nidd5 has a potent effect on adiposity in the TSOD mouse .
Mizutani, S., Gomi, H., Hirayama, I., and Izumi, T.
Mammalian Genome 17:375-387, 2006
# Granuphilin molecularly docks insulin granules to the fusion machinery.
Gomi, H., Mizutani, S., Kasai, K., Itohara, S., and Izumi, T.
J. Cell Biol., 171, 99-109, 2005
# Glucose intolerance in young TallyHo mice is induced by leptin-mediated inhibition of insulin secretion.
Sung, Y.Y., Lee, Y.S., Jung, W.H., Kim, H.G. Cheon, H., Hyae, G.C., Yang, S.D., and Sang, D.R.
Biochem Biophys Res Commun 338: 1779-1787, 2005
# Rab27a mediates the tight docking of insulin granules onto the plasma membrane during glucose stimulation
Kasai, K., Ohara-Imaizumi, M., Takahashi, N., Mizutani, S., Zhao, S., Kikuta, T., Kasai, H., Nagamatsu, S., Gomi, H., and Izumi, T.
J Clin Invest.: 115(2): 388-396, 2005
# A series of maturity onset diabetes of the young, type 2 (MODY2) mouse models generated by a large-scale ENU mutagenesis program
Inoue, M., Sakuraba, Y., Motegi, H., Kubota, N.,, Toki, H., Matsui, J., Toyoda, Y., Miwa, I., Terauchi, Y., Kadowaki, T., Shigeyama, Y., Kasuga, M., Adachi, T., Fujimoto, N., Matsumoto, R., Tsuchihashi, K., Kagami, T., Inoue, A., Kaneda, H., Ishijima, J., Masuya, H., Suzuki, T., Wakana, S., Gondo, Y., Minowa, O., Shiroishi, T., and Noda, T.
Human Molecular Genetics 13:1147-1157, 2004
# Effects of malted barley extract and banaba extract on blood glucose levels in genetically diabetic mice.
Hong, H., and Maeng W.J.
J Med Food 7: 487-490, 2004
# Relationship between the preference for Sake (Japanese rice wine) and the movements of metabolic parameters coinciding with sake intake.
Manabe, Y., Utsunomiya, H., Gotoh, K., Kurosu, T., and Fushiki, T.
Bioscience Biotechnology and Biochemistry 68: 796-802, 2004
# Gastric inhibitory polypeptide is the major insulinotropic factor in KATP null mice
Tsukiyama, K., Yamada Y., Miyawaki, K., Hamasaki, A., Nagashima, K., Hosokawa, M.,
Fujimoto, S., Takahashi, A., Toyoda, K., Toyokuni, S., Oiso, Y., and Seino Y.
European J. Endocrinol., 151, 407-412, 2004.
# Hyperinsulinemia, glucose intolerance, and dyslipidemia induced by acute inhibition of phosphoinositide 3-kinase signaling in the liver
Miyake, K., Ogawa, W., Matsumoto, M., Nakamura, T., Sakaue, H., and Kasuga, M.
J. Clin. Invest. 110:1483-1491, 2002
#LOSS OF GRANUPHILIN AND OF SYNTAXIN-1A CAUSE DIFFERENTIAL EFFECTS ON INSULIN GRANULE DOCKING AND FUSION
H. Wang., R. Ishizaki., E. Kobayashi., T. Fujiwara., K. Akagawa., and T.Izumi1.
The Journal of Biological Chemistry.286(31).2011
#Rapid Rehydration and Moderate Plasma Glucose Elevation by Fluid Containing Enzymatically Synthesized Glycogen
K. Inagaki., K. Ishihara., M. Ishida., A. Watanabe., M. Fujiwara., Y. Komatsu., M. Shirai., Y. Kato., A. Takanezawa., T. Furuwashiki., H. Takata., and Y. Seyama.
Journal of Nutritional Science and Vitaminology.Vol. 57 (2011) , No. 2 pp.170-176
#Dynamic modification of sphingomyelin in lipid microdomains controls development of obesity, fatty liver, and type 2 diabetes
S. Mitsutake., K. Zama., H. Yokota.,T. Yoshida., M. Tanaka., M. Mitsui., M. Ikawa., M. Okabe., Y. Tanaka., T. Yamashita., H. Takemoto., T. Okazaki., K. Watanabe., and Y. Igarashi.
The Journal of Biological Chemistry.286(31).2011
# PPARaactivation is essential for HCV core protein-induced hepatic steatosis and hepatocellular carcinoma in mice.
Tanaka, N., Moriya, K., Kiyosawa, K., Koike, K., Gonzalez, F.J. and Aoyama, T.
J Clin Invest 118: 683-694, 2008
#Transgenic expression of a mutated cyclin-dependent kinase 4(CDK4/R24G)
in pancreatic β-cells prevents progression of diabetes in db/db mice
Miyawaki,K.,Inoue,H.,Keshavarz,P.,Mizuta,K.,Sato,A.,Sakamoto,Y.,Moritani,M.,
Kunika,K.,Tanahashi,T.and Itakura,M.
Diabetes Research and Clinical Practice 82,33-41,2008
# Hypoglycemic effects of exopolysaccharides produced by mycelial cultures of two different mushrooms Tremella fuciformis and Phellinus baumii in ob/ob mice.
Cho, E.J., Hwang, H.J., Kim, S.W., Oh , J.Y., Baek, Y.M., Choi, J.W., Bae, S.H., and Yun, J.W.
Applied Microbiol Biotechnol , 75: 1257-1265, 2007
# Schnurri-2 controls BMP-dependent adipogenesis via interaction with Smad proteins.
Jin, W., Takagi, T., Kanesashi, S., Kurahashi, T., Nomura, T., Harade, J., and Ishii, S.
Developmental Cell, 10: 461-471, 2006
# Chromosome 2 locus Nidd5 has a potent effect on adiposity in the TSOD mouse .
Mizutani, S., Gomi, H., Hirayama, I., and Izumi, T.
Mammalian Genome 17:375-387, 2006
# Granuphilin molecularly docks insulin granules to the fusion machinery.
Gomi, H., Mizutani, S., Kasai, K., Itohara, S., and Izumi, T.
J. Cell Biol., 171, 99-109, 2005
# Glucose intolerance in young TallyHo mice is induced by leptin-mediated inhibition of insulin secretion.
Sung, Y.Y., Lee, Y.S., Jung, W.H., Kim, H.G. Cheon, H., Hyae, G.C., Yang, S.D., and Sang, D.R.
Biochem Biophys Res Commun 338: 1779-1787, 2005
# Rab27a mediates the tight docking of insulin granules onto the plasma membrane during glucose stimulation
Kasai, K., Ohara-Imaizumi, M., Takahashi, N., Mizutani, S., Zhao, S., Kikuta, T., Kasai, H., Nagamatsu, S., Gomi, H., and Izumi, T.
J Clin Invest.: 115(2): 388-396, 2005
# A series of maturity onset diabetes of the young, type 2 (MODY2) mouse models generated by a large-scale ENU mutagenesis program
Inoue, M., Sakuraba, Y., Motegi, H., Kubota, N.,, Toki, H., Matsui, J., Toyoda, Y., Miwa, I., Terauchi, Y., Kadowaki, T., Shigeyama, Y., Kasuga, M., Adachi, T., Fujimoto, N., Matsumoto, R., Tsuchihashi, K., Kagami, T., Inoue, A., Kaneda, H., Ishijima, J., Masuya, H., Suzuki, T., Wakana, S., Gondo, Y., Minowa, O., Shiroishi, T., and Noda, T.
Human Molecular Genetics 13:1147-1157, 2004
# Effects of malted barley extract and banaba extract on blood glucose levels in genetically diabetic mice.
Hong, H., and Maeng W.J.
J Med Food 7: 487-490, 2004
# Relationship between the preference for Sake (Japanese rice wine) and the movements of metabolic parameters coinciding with sake intake.
Manabe, Y., Utsunomiya, H., Gotoh, K., Kurosu, T., and Fushiki, T.
Bioscience Biotechnology and Biochemistry 68: 796-802, 2004
# Gastric inhibitory polypeptide is the major insulinotropic factor in KATP null mice
Tsukiyama, K., Yamada Y., Miyawaki, K., Hamasaki, A., Nagashima, K., Hosokawa, M.,
Fujimoto, S., Takahashi, A., Toyoda, K., Toyokuni, S., Oiso, Y., and Seino Y.
European J. Endocrinol., 151, 407-412, 2004.
# Hyperinsulinemia, glucose intolerance, and dyslipidemia induced by acute inhibition of phosphoinositide 3-kinase signaling in the liver
Miyake, K., Ogawa, W., Matsumoto, M., Nakamura, T., Sakaue, H., and Kasuga, M.
J. Clin. Invest. 110:1483-1491, 2002
| Page top |
Mouse Insulin ELISA KIT (S-type) (AKRIN-011S)
Original reports
#Anti-Diabetic Effects of a Kaempferol Glycoside-Rich Fraction from Unripe Soybean (Edamame,Glycine max L.Merrill.'Jindai') Leaves on KK-Ay Mice
Y. Zang., H. Sato., K. Igarashi.
Biosci.Biotechnol.Biochem,75(9),1677-1684,2011
#Anti-Diabetic Effects of a Kaempferol Glycoside-Rich Fraction from Unripe Soybean (Edamame,Glycine max L.Merrill.'Jindai') Leaves on KK-Ay Mice
Y. Zang., H. Sato., K. Igarashi.
Biosci.Biotechnol.Biochem,75(9),1677-1684,2011
| Page top |
Dog Insulin ELISA KIT (AKRIN-012T)
Original reports
#Predisposition for primary hyperlipidemia in Miniature Schnauzers and Shetland sheepdogs as compared to other canine breeds
Mori,M.,Lee,P.,Muranaka,S.,Sagara,F.,Takemitsu,H.,Nishiyama,Y.,Yamamoto,I.,Yagishita,M.,Arai,T.
Research in Veterinary Science, Volume 88, Issues 3, June 2010, 394-399
#Effect of Distal Subtotal Gastrectomy With Preservation of the Celiac Branch of the Vagus
Nerve to Gastrointestinal Function
Ando,H.,Mochiki,E.,Ohno,T.,Kogure,N.,Tanaka,N.,Tabe,Y.,Kimura,H.,Kamiyama,Y.,Aihara,R.,
Nakabayashi,T.,Asano,T.,Aomori,T.,Fujita,Y.,Kuwano,H.
Annals of Surgery,Volume 247, 2008
#Predisposition for primary hyperlipidemia in Miniature Schnauzers and Shetland sheepdogs as compared to other canine breeds
Mori,M.,Lee,P.,Muranaka,S.,Sagara,F.,Takemitsu,H.,Nishiyama,Y.,Yamamoto,I.,Yagishita,M.,Arai,T.
Research in Veterinary Science, Volume 88, Issues 3, June 2010, 394-399
#Effect of Distal Subtotal Gastrectomy With Preservation of the Celiac Branch of the Vagus
Nerve to Gastrointestinal Function
Ando,H.,Mochiki,E.,Ohno,T.,Kogure,N.,Tanaka,N.,Tabe,Y.,Kimura,H.,Kamiyama,Y.,Aihara,R.,
Nakabayashi,T.,Asano,T.,Aomori,T.,Fujita,Y.,Kuwano,H.
Annals of Surgery,Volume 247, 2008
| Page top |
Monkey Insulin ELISA KIT (AKRIN-014T)
Original reports
# Characterization of obesity in Japanese monkeys (Macaca fuscata) in a pedigreed colony.
Takahashi, T., Higashino, A., Takagi, K., Kamanaka, Y., Abe, M., Morimoto, M., Kang, K.H., Goto, S., Suzuki, J., Hamada, Y., and Kageyama, T.
Primatology 35: 30-37, 2006
# Effect of fructose-rich high-fat diet on glucose sensitivity and atherosclerosis in nonhuman primate.
Suzuki, M., Yamamoto, D., Suzuki, T., Fujii, M., Suzuki, N., Fujishiro, M., Sakurai, T., and Yamada, K.
Methods Find Exp Clin Pharmacol 28: 609-617, 2006
# High fat and high fructose diet induced intracranial atherosclerosis and enhanced vasoconstrictor responses in non-human primate.
Suzuki, M., Yamamoto, D., Suzuki, T., Fujii, M., Suzuki, N., Fujishiro, M., Sakurai, T., and Yamada, K.
Life sciences 80: 200-204, 2006
# Characterization of obesity in Japanese monkeys (Macaca fuscata) in a pedigreed colony.
Takahashi, T., Higashino, A., Takagi, K., Kamanaka, Y., Abe, M., Morimoto, M., Kang, K.H., Goto, S., Suzuki, J., Hamada, Y., and Kageyama, T.
Primatology 35: 30-37, 2006
# Effect of fructose-rich high-fat diet on glucose sensitivity and atherosclerosis in nonhuman primate.
Suzuki, M., Yamamoto, D., Suzuki, T., Fujii, M., Suzuki, N., Fujishiro, M., Sakurai, T., and Yamada, K.
Methods Find Exp Clin Pharmacol 28: 609-617, 2006
# High fat and high fructose diet induced intracranial atherosclerosis and enhanced vasoconstrictor responses in non-human primate.
Suzuki, M., Yamamoto, D., Suzuki, T., Fujii, M., Suzuki, N., Fujishiro, M., Sakurai, T., and Yamada, K.
Life sciences 80: 200-204, 2006
| Page top |
Rabbit Insulin Standard (ASIN-003)
Original reports
# Erythrophagocytosis by Liver Macrophages(Kupffer Cells)Promotes Oxidative Stress, Inflammation,and Fibrosis in a Rabbit Model of Steatohepatitis
Otogawa,K.,Kinoshita,K.,Fujii,H.,Sakabe,M.,Shiga,R.,Nakatani,K.,Ikeda,K.,Nakajima,Y.,
Ikura,Y.,Ueda,M.,Arakawa,T.,Hato,F., and Kawada,N.
American Journal of Pathology. 170:967-980, 2007
# Erythrophagocytosis by Liver Macrophages(Kupffer Cells)Promotes Oxidative Stress, Inflammation,and Fibrosis in a Rabbit Model of Steatohepatitis
Otogawa,K.,Kinoshita,K.,Fujii,H.,Sakabe,M.,Shiga,R.,Nakatani,K.,Ikeda,K.,Nakajima,Y.,
Ikura,Y.,Ueda,M.,Arakawa,T.,Hato,F., and Kawada,N.
American Journal of Pathology. 170:967-980, 2007
| Page top |
Cat Insulin ELISA KIT (AKRIN-015)
Original reports
#Obesity induced changes to plasma adiponectin concentration and cholesterol lipoprotein composition profile in cats
Muranaka,S.,Mori,N.,Hatano,Y.,Saito,T.R.,Lee,P., Kojima,M.,Kigure,M.,Yagishita,M.,Arai,T.
Veterinary Science,2010
#Decreased gene expression of insulin signaling genes in insulin sensitive tissues of obese cats
Mori,N.,Lee,P.,Takemitsu,H.,Iwasaki,E.,Kimura,N.,Yagishita,M.,Hayasaka,M.,Arai,T.
Vet Res Commun,33:315-329,2009
#Hypertriglyceridemia with increased plasma insulin concentrations in cats
Hatano,Y.,Mori,N.,Asada,M.,Mori,M.,Yamamoto,I.,Muranaka,S.,Kojima,M.,Kigure,M.,
Yagishita,M.,Sako,T.,Arai,T.
Research in Veterinary Science.88(2010)458-460
#Presence of anti-insulin natural autoantibodies in healthy cats and its interference with immunoassay for serum insulin concentrations
Nishii,N.,Takasu,M.,Kojima,M.,Hachisu,T.,Wakabayashi,K.,Iwasawa,A.,Maeda,S.,Ohba,Y.,
Kitagawa,H.
Domestic Animal Endocrinology 38,138-145(2010)
#Measurement of feline plasma insulin concentrations by use of ELISA
Nishii,N.,Takasu,M.,Okkar.S.,Maeda,S.,Ohba,Y.,Kojima,M.,Hachisu,T.,Kitagawa,H.
Journal of Japanese Veterinary Medical Association 60,290-293(2007)
#Obesity induced changes to plasma adiponectin concentration and cholesterol lipoprotein composition profile in cats
Muranaka,S.,Mori,N.,Hatano,Y.,Saito,T.R.,Lee,P., Kojima,M.,Kigure,M.,Yagishita,M.,Arai,T.
Veterinary Science,2010
#Decreased gene expression of insulin signaling genes in insulin sensitive tissues of obese cats
Mori,N.,Lee,P.,Takemitsu,H.,Iwasaki,E.,Kimura,N.,Yagishita,M.,Hayasaka,M.,Arai,T.
Vet Res Commun,33:315-329,2009
#Hypertriglyceridemia with increased plasma insulin concentrations in cats
Hatano,Y.,Mori,N.,Asada,M.,Mori,M.,Yamamoto,I.,Muranaka,S.,Kojima,M.,Kigure,M.,
Yagishita,M.,Sako,T.,Arai,T.
Research in Veterinary Science.88(2010)458-460
#Presence of anti-insulin natural autoantibodies in healthy cats and its interference with immunoassay for serum insulin concentrations
Nishii,N.,Takasu,M.,Kojima,M.,Hachisu,T.,Wakabayashi,K.,Iwasawa,A.,Maeda,S.,Ohba,Y.,
Kitagawa,H.
Domestic Animal Endocrinology 38,138-145(2010)
#Measurement of feline plasma insulin concentrations by use of ELISA
Nishii,N.,Takasu,M.,Okkar.S.,Maeda,S.,Ohba,Y.,Kojima,M.,Hachisu,T.,Kitagawa,H.
Journal of Japanese Veterinary Medical Association 60,290-293(2007)
| Page top |
Mouse C-peptide ELISA KIT (U-type)(AKRCP-031)
Original reports
#Therapeutic approach for type 1 diabetes mellitus using the novel immunomodulator FTY720 (fingolimod) in combination with once-daily injection of insulin glargine in non-obese diabetic mice
T, Tsuji., M, Inoue., Y, Yoshida., T, Fujita., Y, Kaino., T, Kohno.
Journal of Diabetes Investigation, published online: 20 SEP 2011
#Intramedullary Cavity as an Implant Site for Bioartificial Pancreas: An In Vivo Study on Diabetic Canine
Y, Kai-Chiang., W, Chang-Chin., S, Shoichiro., K, Tzong-Fu., L, Sheng-Chuan., L, Feng-Huei.
Transplantation, 27 September 2010, Vol. 90, Issue 6, 604-611
#The in vivo performance of bioartificial pancreas in bone marrow cavity: A case report of a spontaneous diabetic feline
K, C, Yang., C, C, Wu., S, C, Lin., S, Sumi., F, H, Lin.
Biochemical and Biophysical Research Communications, Vol. 393, Issue 3, 12 March 2010, Pages 362-364
#In vitro reprogramming of adult hepatocytes into insulin-producing cells without viral vectors
H, Motoyama., S, Ogawa., A, Kubo., S, Miwa., J, Nakayama., Y, Tagawa., S, Miyagawa
Biochemical and Biophysical Research Communications,Vol. 385, Issue 1, 17 July 2009, Pages 123-128
# Efficient differentiation of insulin-producing cells from skin-derived stem cells.
Guo,W.,Miao,C.,Liu,S.,Qiu,Z.,Li,J., and Duan, E.
Cell Proliferation, Volume 42, Issue 1, pp.49-62, 2009
#Enrichment of Putative Pancreatic Progenitor Cells From Mice by
Sorting for Prominin1(CD133)and PDGFRb
Yuichi Hori,Miki Fukomoto,Yoshikazu Kuroda.Stem Cells;0:2008-0192v1,2008
#Possibility of insulin-producing cells derived from mouse embryonic stem cells for diabetes treatment
T, Ibii., H, Shimada., S, Miura., E, Fukuma., H, Sato., H, Iwata.
Journal of Bioscience and Bioengineering,Vol. 103, Issue 2, February 2007, Pages 140-146
# The dual function of hepatic SOCS3 in insulin resistance in vivo
Torisu, T., Sato, N., Yoshiga, D., Kobayashi, T., Yoshioka, T., Mori, H., Iida, M. and Yoshimura, A.
Genes to Cells, 12, 143-154, 2007
# Prolonged remission of diabetes by regeneration of bold italic beta cells in diabetic mice treated with recombinant adenoviral vector expressing glucagon-like peptide-1.
Liu, M.J., Shin, S., Li, N., Shigehara, T., Lee, Y.S., Yoon, J.W., and Jun H.S.
Molecular Therapy 15: 86-93, 2007
# Possibility of insulin-producing cells derived from mouse embryonic stem cells for diabetes treatment
Ibii, T., Shimada, H, Miura, S., Fukuma, E.,Sato, H.,and Iwata,H.
J Bioscience Bioengineering 103:140-146, 2007
# A human b-cell line for transplantation therapy to control type 1 diabetes
Narushima, M., Kobayashi, N., Okitsu, T., Tanaka, Y., Li, S.A., Chen, Y., Miki, A., Tanaka, K., Nakaji, S., Takei, K., Gutierrez, A.S., Rivas-Carrillo, J.D., Navarro-Alvarez, N., Jun, H.S., Westerman, K.A., Noguchi, H., Lakey, J.R.T.,, Leboulch, P., Tanaka, N., and Yoon, J.W.
Nature Biotechnology 23(10): 1274-1282, 2005
#Therapeutic approach for type 1 diabetes mellitus using the novel immunomodulator FTY720 (fingolimod) in combination with once-daily injection of insulin glargine in non-obese diabetic mice
T, Tsuji., M, Inoue., Y, Yoshida., T, Fujita., Y, Kaino., T, Kohno.
Journal of Diabetes Investigation, published online: 20 SEP 2011
#Intramedullary Cavity as an Implant Site for Bioartificial Pancreas: An In Vivo Study on Diabetic Canine
Y, Kai-Chiang., W, Chang-Chin., S, Shoichiro., K, Tzong-Fu., L, Sheng-Chuan., L, Feng-Huei.
Transplantation, 27 September 2010, Vol. 90, Issue 6, 604-611
#The in vivo performance of bioartificial pancreas in bone marrow cavity: A case report of a spontaneous diabetic feline
K, C, Yang., C, C, Wu., S, C, Lin., S, Sumi., F, H, Lin.
Biochemical and Biophysical Research Communications, Vol. 393, Issue 3, 12 March 2010, Pages 362-364
#In vitro reprogramming of adult hepatocytes into insulin-producing cells without viral vectors
H, Motoyama., S, Ogawa., A, Kubo., S, Miwa., J, Nakayama., Y, Tagawa., S, Miyagawa
Biochemical and Biophysical Research Communications,Vol. 385, Issue 1, 17 July 2009, Pages 123-128
# Efficient differentiation of insulin-producing cells from skin-derived stem cells.
Guo,W.,Miao,C.,Liu,S.,Qiu,Z.,Li,J., and Duan, E.
Cell Proliferation, Volume 42, Issue 1, pp.49-62, 2009
#Enrichment of Putative Pancreatic Progenitor Cells From Mice by
Sorting for Prominin1(CD133)and PDGFRb
Yuichi Hori,Miki Fukomoto,Yoshikazu Kuroda.Stem Cells;0:2008-0192v1,2008
#Possibility of insulin-producing cells derived from mouse embryonic stem cells for diabetes treatment
T, Ibii., H, Shimada., S, Miura., E, Fukuma., H, Sato., H, Iwata.
Journal of Bioscience and Bioengineering,Vol. 103, Issue 2, February 2007, Pages 140-146
# The dual function of hepatic SOCS3 in insulin resistance in vivo
Torisu, T., Sato, N., Yoshiga, D., Kobayashi, T., Yoshioka, T., Mori, H., Iida, M. and Yoshimura, A.
Genes to Cells, 12, 143-154, 2007
# Prolonged remission of diabetes by regeneration of bold italic beta cells in diabetic mice treated with recombinant adenoviral vector expressing glucagon-like peptide-1.
Liu, M.J., Shin, S., Li, N., Shigehara, T., Lee, Y.S., Yoon, J.W., and Jun H.S.
Molecular Therapy 15: 86-93, 2007
# Possibility of insulin-producing cells derived from mouse embryonic stem cells for diabetes treatment
Ibii, T., Shimada, H, Miura, S., Fukuma, E.,Sato, H.,and Iwata,H.
J Bioscience Bioengineering 103:140-146, 2007
# A human b-cell line for transplantation therapy to control type 1 diabetes
Narushima, M., Kobayashi, N., Okitsu, T., Tanaka, Y., Li, S.A., Chen, Y., Miki, A., Tanaka, K., Nakaji, S., Takei, K., Gutierrez, A.S., Rivas-Carrillo, J.D., Navarro-Alvarez, N., Jun, H.S., Westerman, K.A., Noguchi, H., Lakey, J.R.T.,, Leboulch, P., Tanaka, N., and Yoon, J.W.
Nature Biotechnology 23(10): 1274-1282, 2005
| Page top |
Rat C-peptide ELISA KIT (U-type)(AKRCP-030)
Original reports
#The in vivo performance of polyvinyl alcohol macro-encapsulated islets
Z,Qi, Y, Shen., G, Yanai., K, Yang., Y, Shirouzu., A, Hiura., S, Sumi
Biomaterials,Vol. 31, Issue 14, May 2010, Pages 4026-4031
#The a-glucosidase inhibitor miglitol delays the development of diabetes and dysfunctional insulin secretion in pancreatic b-cells in OLETF rats
N, Fukaya., K, Mochizuki., Y, Tanaka., T, Kumazawa., Z, Jiuxin., M, Fuchigami., T, Goda.
European Journal of Pharmacology, Vol. 624, Issues 1-3, 10 December 2009, Pages 51-57
#A NOVEL PATHWAY OF INSULIN SENSITIVITY IN CHROMOGRANIN A NULL MICE:
A CRUCIAL ROLE FOR RANCREASTATIN IN GLUCOSE HOMEOSTASIS
J.R.Gayen,M.Saberi,S.Schenk,N.Biswas,S.M.Vaingankar,W.W.Cheung,S.M.Najjar,
D.T.O'Connor,G.Bandyopadhyay,and S.K.Mahata
The Journal of Biological Chemistry,284(42):28498-509,2009
#The in vivo performance of polyvinyl alcohol macro-encapsulated islets
Z,Qi, Y, Shen., G, Yanai., K, Yang., Y, Shirouzu., A, Hiura., S, Sumi
Biomaterials,Vol. 31, Issue 14, May 2010, Pages 4026-4031
#The a-glucosidase inhibitor miglitol delays the development of diabetes and dysfunctional insulin secretion in pancreatic b-cells in OLETF rats
N, Fukaya., K, Mochizuki., Y, Tanaka., T, Kumazawa., Z, Jiuxin., M, Fuchigami., T, Goda.
European Journal of Pharmacology, Vol. 624, Issues 1-3, 10 December 2009, Pages 51-57
#A NOVEL PATHWAY OF INSULIN SENSITIVITY IN CHROMOGRANIN A NULL MICE:
A CRUCIAL ROLE FOR RANCREASTATIN IN GLUCOSE HOMEOSTASIS
J.R.Gayen,M.Saberi,S.Schenk,N.Biswas,S.M.Vaingankar,W.W.Cheung,S.M.Najjar,
D.T.O'Connor,G.Bandyopadhyay,and S.K.Mahata
The Journal of Biological Chemistry,284(42):28498-509,2009
| Page top |
GLP-1(Active) ELISA KIT(AKMGP-011)
Original reports
#DPP-4 inhibitor des-F-sitagliptin treatment increased insulin exocytosis from db/db mice b cells
S. Nagamatsu., M. Ohara-Imaizumi., Y. Nakamichi., K.,Aoyagi.,C. Nishiwaki.
Biochemical and Biophysical Research Communications Vol.412,Issue4,9 September 2011,556-560
#Mate Tea(Ilex paraguariensis)Promotes Satiety and Body Weight Lowering in Mice:Involvement of Glucagon-Like Peptide-1
G, M, E, Hussein., H, Matsuda., S, Nakamura., M, Hamao., T, Akiyama., K, Tamura., and M, Yoshikawa.
Biol.Pharm.Bull.34(12)1849-1855,2011
#5-Hydroxy-eicosapentaenoic acid is an endogenous GPR119 agonist and enhances glucose-dependent insulin secretion
R, Kogure., K, Toyama., S, Hiyamuta., I, Kojima., S, Takeda.
Biochemical and Biophysical Research Communications Vol.416,Issue1-2,58-63,2011
#GLP-1 Secretion in Response to Oral and Luminal Palatinose (Isomaltulose) in Rats
T,Hira.,M,Muramatsu.,M,Okuno.and H,Hara.
J Nutr Sci Vitaminol Vol.57,30-35,2011
#Trehalose prevents adipocyte hypertrophy and mitigates insulin resistance
C,Arai.,N,Arai.,A,Mizote.,K,Kohno.,K,Iwaki.,T,Hanaya.,S,Arai.,S,Ushio.,S,Fukuda.
Nutrition Research Vol.30,Issue12,840-848,2010
#Imaging exocytosis of single glucagon-like peptide-1 containing granules
in a murine enteroendocrine cell line with total internal reflection
fluorescent microscopy
Ohara-Imaizumi,M.,Aoyagi,K.,Akimoto,Y.,Nakamichi,Y.,Nishiwaki,C.,Kawakami,H.
and Nagamatsu,S.
Biochemical and Biophysical Reseach Communications 390,16-20,2009
#DPP-4 inhibitor des-F-sitagliptin treatment increased insulin exocytosis from db/db mice b cells
S. Nagamatsu., M. Ohara-Imaizumi., Y. Nakamichi., K.,Aoyagi.,C. Nishiwaki.
Biochemical and Biophysical Research Communications Vol.412,Issue4,9 September 2011,556-560
#Mate Tea(Ilex paraguariensis)Promotes Satiety and Body Weight Lowering in Mice:Involvement of Glucagon-Like Peptide-1
G, M, E, Hussein., H, Matsuda., S, Nakamura., M, Hamao., T, Akiyama., K, Tamura., and M, Yoshikawa.
Biol.Pharm.Bull.34(12)1849-1855,2011
#5-Hydroxy-eicosapentaenoic acid is an endogenous GPR119 agonist and enhances glucose-dependent insulin secretion
R, Kogure., K, Toyama., S, Hiyamuta., I, Kojima., S, Takeda.
Biochemical and Biophysical Research Communications Vol.416,Issue1-2,58-63,2011
#GLP-1 Secretion in Response to Oral and Luminal Palatinose (Isomaltulose) in Rats
T,Hira.,M,Muramatsu.,M,Okuno.and H,Hara.
J Nutr Sci Vitaminol Vol.57,30-35,2011
#Trehalose prevents adipocyte hypertrophy and mitigates insulin resistance
C,Arai.,N,Arai.,A,Mizote.,K,Kohno.,K,Iwaki.,T,Hanaya.,S,Arai.,S,Ushio.,S,Fukuda.
Nutrition Research Vol.30,Issue12,840-848,2010
#Imaging exocytosis of single glucagon-like peptide-1 containing granules
in a murine enteroendocrine cell line with total internal reflection
fluorescent microscopy
Ohara-Imaizumi,M.,Aoyagi,K.,Akimoto,Y.,Nakamichi,Y.,Nishiwaki,C.,Kawakami,H.
and Nagamatsu,S.
Biochemical and Biophysical Reseach Communications 390,16-20,2009
| Page top |
Apolipoprotein B48 ELISA kits (AKHB48)
Original reports
#Dietary Hesperidin Exerts Hypoglycemic and Hypolipidemic Effects in Streptozocin-Induce Marginal Type 1 Diabetic Rats
Akiyama,S., Katsumata,S., Suzuki,K., Ishimi,Y.,Wu,J., and Uehara,M.
J Clin Biochem Nutr.January;46(1):87-92.2010
#Hypoglycemic and Hypolipidemic Effects of Hesperidin and Cyclodextrin-Clathrated Hesperetin in Goto-Kakizaki Rats with Type 2 Diabetes
Akiyama,S., Katsumata,S., Suzuki,K., Nakayama,Y., Ishimi,Y. and Uehara,M.
Bioscience,Biotechnology,and Biochemistry.Vol.73,No.12 pp.2779-2782(2009)
# Familial Combined Hyperlipidemia Is Associated With Alterations in the Cholesterol Synthesis Pathway
Himbergen, T. M., Otokozawa, S., Matthan, N. R., Schaefer, E. J., Buchsbaum, A., Ai, M., Tits, L. J. H., Graaf, J., Stalenhoef, A. F. H.
Arterioscler Thromb Vasc Biol, 30: 113-120, 2010
# Postprandial apolipoprotein B48 is associated with asymptomatic peripheral arterial disease: A study in patients with type 2 diabetes and controls
Valdivielso, P., Puerta, S., Rioja, J., Alonso, I., Ariza, M. J., Sanchez-Chaparro, M. A., Palacios, R., Gonzalez-Santos, P.
Clinica Chimica Acta, Volume 411, Issues 5-6, 2 March, 2010, 433-437
# Chylomicronemia With a Mutant GPIHBP1 (Q115P) That Cannot Bind Lipoprotein Lipase
Beigneux, A. P., Franssen, R., Bensadoun, A., Gin, P., Melford. K., Peter, J., Walzem, R. L., Weinstein, M. M., Davies, B. S. J., Kuivenhoven, J. A., Kastelein, J. J. P., Fong, L. G., Dallinga-Thie, G. M., Young, A. G.
Arterioscler Thromb Vasc Biol, 29: 956-962, 2009
# Omega 3 fatty acids induce a markerd reduction of
apolipoprotein B48 when added to fluvastatin in
patients with type 2 diabetes and mixed hyperlipidemia
Valdivielso,P.,Rioja,J.,Garcia-Arias,C.,Sanchez-Chaparro,MA.,Gonzalez-Santos,P.
Cardiovasc Diabetol,8;8:1,2009
# Fasting and postprandial apolipoprotein B-48 levels in healthy,obese,and hyperlipidemic subjects
Otokozawa,S.,Ai,M., Diffenderfer,MR., Asztalos,BF.,Tanaka,A., Lamon-Fava,S., Schaefer,EJ.
Metabolism Clinical and Experimental . Volume 58, Issues 11, November, 2009, 1536-1542
#Detection of apolipoprotein B-48 and B-100 carrying particles in lipoprotein fractions extracted from human aortic atherosclerotic plaques in sudden cardiac death cases.
Nakano, T., Nakajima, K., Niimi, M., Fujita, M.Q., Nakajima, Y., Takeichi, S, Kinoshita, M., Matsushima, T., Teramoto, T., and Tanaka, A.
Clinica Chimica Acta 390, 38-43, 2008.
#Plasma fasting and postprandial apolipoprotein B48 are increased only
in type2 diabetes with atherosclerosclerosis
P.Valdivielso,J.Rioja,S.Puerta,M.J.Ariza-Corbo,M.A.Sanchez-Chaparro,
I.Alonso and P.Gonzalez-Santos
Atherosclerosis Supplements Vol.9,issue2,September 2008,87-88
# Postprandial Hyperlipidemia and Atherosclerosis
Teramoto, T.
Atherosclerosis Supplements 9, 83-102, 2008
# Decreased lipoprotein lipase activity and increased postprandial concentrations of triglyceride-rich lipoproteins in offspring of elderly survivors of myocardial infarction.
Lakhal, S., Borvik, T., Nordoy, A., and Hansen, J.B.
Nutrition, Metabolism and Cardiovascular Diseases (Epub ahead of print), 2008
#Effects of Intensive Atorvastatin,Rosuvastatin Treatment on Apolipoprotein
B-48 and Remnant Lipoprotein Cholesterol Levels Seiko Otokozawa,Masumi Ai,Thomas Van Himbergen,Bela F.Asztalos,Akira Tanaka,
Evan A.Stein,Peter H.Jones and Ernst J.Schaefer
Atheroscleroisis,In Press,Accepted Manuscript,Available online 12 November 2008
#Extended-Release Niacin Alters the Metabolism of Plasma Apolipoprotein(Apo)A-I-and
ApoB-Containing Lipoproteins.
Lamon-Fava S,Diffenderfer MR,Barrett PH,Buchsbaum A,Nyaku M,Horvath KV,Asztalos BF,
Otokozawa S,Ai M,Matthan NR,Lichtenstein AH,Dolnikowski GG,Schaefer EJ.
Arterioscler Thromb Vasc Biol.2008 Jun 19.
#ApoB-100 carrying lipoprotein, but not apoB-48, is the major subset of proatherogenic remnant-like lipoprotein particles detected in plasma of sudden cardiac death cases.
Nakajima, K., Nakajima, Y., Takeichi, S., and Fijita, M.Q.
Atherosclerosis 194, 473-482, 2007.
# Involvement of intestinal alkaline phosphatase in serum apolipoprotein B-48 level and its association with ABO and secretor blood group types
Nakano, T., Shimanuki, T., Matsushita, M., Koyama, I., Inoue, I., Katayama, S., Alpers, D. H., Komoda, T.
Biochemical and Biophysical Research Communications, 341, 33-38, 2006
# Determination of apolipoprotein B-48 in serum by a sandwich ELISA
Kinoshita, M., Kojima, M., Matsushima, T., and Teramoto, T.
Clinica Chimaca Acta, 351, 115-120, 2005.
Presentations at scientific meetings
# Fasting and Postprandial Apo-B48 are Increased in Patients with Type 2 diabetes with Atherosclerosis
Valdivielso, P., Puerta, S., Rioja, J., Ariza, M., Hornos, A., Garcia-Arias, C., Sanchez-Chaparro, M., Gonzalez-Santos, P.(Univ. of Malaga)
77th Congress of the European Atherosclerosis Society, April 26-29, 2008, Istanbul, Turkey, Poster sessions, PO20-228
# Reduced Postprandial Concentration of Apolipoprotein B-48 with Camelina Oil
Vaananen, M., Ahotupa, M., Vasankari, T. M., Vasankari, T. J.(University of Turku)
76th Congress of the European Atherosclerosis Society, June 10-13, 2007, Helsinki, Finland, Poster sessions, PO20-619
# Apolipoprotein B-48 in Lipoprotein Fraction Extracted from Human Aortic Plaque and Plasma from Sudden Cardiac Death Cases
Nakano, T., Niimi, M., Nakajima, K., Fujita, M., Nakajima, Y., Takeichi, S., Tanaka, A., Matsushima, T., Kinoshita, M,. Teramoto, T.
(Jimro Co., Ltd., Keio Univ., Tokai Univ., Kagawa Nutrition Univ., Tsukuba Memorial Hospital., Teikyo Univ.)
76th Congress of the European Atherosclerosis Society, June 10-13, 2007, Helsinki, Finland, Poster sessions, PO3-63
# Concentration of Apolipoprotein B48 in Fasting Serum is an Important Marker of Postrandial Hyperlipidemia
Takenaka, H., Kinoshita, H., Maeda, T., Taki, M., Takao, K., Kusano, J., Yoshimura, N., Fujita, M., Teramoto, T.(Teikyo Univ. Sch. Of Med.)
XIV International Symposium on Atherosclerosis, Rome, Italy, June 18-22, 2006 Poster Session, Th-P15:76
# Concentration of apolipoprotein B48 in fasting serum is an important marker of postprandial hyperlipidemia.
Hirota, D., Kinosita, M., Maeda, T., suda, T., Taki, M., Kusano, J., Takenaka, H., Yoshimura,
N., and Teramoto, T.(Teikyo Univ. Sch. of Med. Int. Med.)
The 37th Japan Atherosclerosis Society Annual Meeting, 2005, English session ES-J8,Proceeding p.185
#Dietary Hesperidin Exerts Hypoglycemic and Hypolipidemic Effects in Streptozocin-Induce Marginal Type 1 Diabetic Rats
Akiyama,S., Katsumata,S., Suzuki,K., Ishimi,Y.,Wu,J., and Uehara,M.
J Clin Biochem Nutr.January;46(1):87-92.2010
#Hypoglycemic and Hypolipidemic Effects of Hesperidin and Cyclodextrin-Clathrated Hesperetin in Goto-Kakizaki Rats with Type 2 Diabetes
Akiyama,S., Katsumata,S., Suzuki,K., Nakayama,Y., Ishimi,Y. and Uehara,M.
Bioscience,Biotechnology,and Biochemistry.Vol.73,No.12 pp.2779-2782(2009)
# Familial Combined Hyperlipidemia Is Associated With Alterations in the Cholesterol Synthesis Pathway
Himbergen, T. M., Otokozawa, S., Matthan, N. R., Schaefer, E. J., Buchsbaum, A., Ai, M., Tits, L. J. H., Graaf, J., Stalenhoef, A. F. H.
Arterioscler Thromb Vasc Biol, 30: 113-120, 2010
# Postprandial apolipoprotein B48 is associated with asymptomatic peripheral arterial disease: A study in patients with type 2 diabetes and controls
Valdivielso, P., Puerta, S., Rioja, J., Alonso, I., Ariza, M. J., Sanchez-Chaparro, M. A., Palacios, R., Gonzalez-Santos, P.
Clinica Chimica Acta, Volume 411, Issues 5-6, 2 March, 2010, 433-437
# Chylomicronemia With a Mutant GPIHBP1 (Q115P) That Cannot Bind Lipoprotein Lipase
Beigneux, A. P., Franssen, R., Bensadoun, A., Gin, P., Melford. K., Peter, J., Walzem, R. L., Weinstein, M. M., Davies, B. S. J., Kuivenhoven, J. A., Kastelein, J. J. P., Fong, L. G., Dallinga-Thie, G. M., Young, A. G.
Arterioscler Thromb Vasc Biol, 29: 956-962, 2009
# Omega 3 fatty acids induce a markerd reduction of
apolipoprotein B48 when added to fluvastatin in
patients with type 2 diabetes and mixed hyperlipidemia
Valdivielso,P.,Rioja,J.,Garcia-Arias,C.,Sanchez-Chaparro,MA.,Gonzalez-Santos,P.
Cardiovasc Diabetol,8;8:1,2009
# Fasting and postprandial apolipoprotein B-48 levels in healthy,obese,and hyperlipidemic subjects
Otokozawa,S.,Ai,M., Diffenderfer,MR., Asztalos,BF.,Tanaka,A., Lamon-Fava,S., Schaefer,EJ.
Metabolism Clinical and Experimental . Volume 58, Issues 11, November, 2009, 1536-1542
#Detection of apolipoprotein B-48 and B-100 carrying particles in lipoprotein fractions extracted from human aortic atherosclerotic plaques in sudden cardiac death cases.
Nakano, T., Nakajima, K., Niimi, M., Fujita, M.Q., Nakajima, Y., Takeichi, S, Kinoshita, M., Matsushima, T., Teramoto, T., and Tanaka, A.
Clinica Chimica Acta 390, 38-43, 2008.
#Plasma fasting and postprandial apolipoprotein B48 are increased only
in type2 diabetes with atherosclerosclerosis
P.Valdivielso,J.Rioja,S.Puerta,M.J.Ariza-Corbo,M.A.Sanchez-Chaparro,
I.Alonso and P.Gonzalez-Santos
Atherosclerosis Supplements Vol.9,issue2,September 2008,87-88
# Postprandial Hyperlipidemia and Atherosclerosis
Teramoto, T.
Atherosclerosis Supplements 9, 83-102, 2008
# Decreased lipoprotein lipase activity and increased postprandial concentrations of triglyceride-rich lipoproteins in offspring of elderly survivors of myocardial infarction.
Lakhal, S., Borvik, T., Nordoy, A., and Hansen, J.B.
Nutrition, Metabolism and Cardiovascular Diseases (Epub ahead of print), 2008
#Effects of Intensive Atorvastatin,Rosuvastatin Treatment on Apolipoprotein
B-48 and Remnant Lipoprotein Cholesterol Levels Seiko Otokozawa,Masumi Ai,Thomas Van Himbergen,Bela F.Asztalos,Akira Tanaka,
Evan A.Stein,Peter H.Jones and Ernst J.Schaefer
Atheroscleroisis,In Press,Accepted Manuscript,Available online 12 November 2008
#Extended-Release Niacin Alters the Metabolism of Plasma Apolipoprotein(Apo)A-I-and
ApoB-Containing Lipoproteins.
Lamon-Fava S,Diffenderfer MR,Barrett PH,Buchsbaum A,Nyaku M,Horvath KV,Asztalos BF,
Otokozawa S,Ai M,Matthan NR,Lichtenstein AH,Dolnikowski GG,Schaefer EJ.
Arterioscler Thromb Vasc Biol.2008 Jun 19.
#ApoB-100 carrying lipoprotein, but not apoB-48, is the major subset of proatherogenic remnant-like lipoprotein particles detected in plasma of sudden cardiac death cases.
Nakajima, K., Nakajima, Y., Takeichi, S., and Fijita, M.Q.
Atherosclerosis 194, 473-482, 2007.
# Involvement of intestinal alkaline phosphatase in serum apolipoprotein B-48 level and its association with ABO and secretor blood group types
Nakano, T., Shimanuki, T., Matsushita, M., Koyama, I., Inoue, I., Katayama, S., Alpers, D. H., Komoda, T.
Biochemical and Biophysical Research Communications, 341, 33-38, 2006
# Determination of apolipoprotein B-48 in serum by a sandwich ELISA
Kinoshita, M., Kojima, M., Matsushima, T., and Teramoto, T.
Clinica Chimaca Acta, 351, 115-120, 2005.
Presentations at scientific meetings
# Fasting and Postprandial Apo-B48 are Increased in Patients with Type 2 diabetes with Atherosclerosis
Valdivielso, P., Puerta, S., Rioja, J., Ariza, M., Hornos, A., Garcia-Arias, C., Sanchez-Chaparro, M., Gonzalez-Santos, P.(Univ. of Malaga)
77th Congress of the European Atherosclerosis Society, April 26-29, 2008, Istanbul, Turkey, Poster sessions, PO20-228
# Reduced Postprandial Concentration of Apolipoprotein B-48 with Camelina Oil
Vaananen, M., Ahotupa, M., Vasankari, T. M., Vasankari, T. J.(University of Turku)
76th Congress of the European Atherosclerosis Society, June 10-13, 2007, Helsinki, Finland, Poster sessions, PO20-619
# Apolipoprotein B-48 in Lipoprotein Fraction Extracted from Human Aortic Plaque and Plasma from Sudden Cardiac Death Cases
Nakano, T., Niimi, M., Nakajima, K., Fujita, M., Nakajima, Y., Takeichi, S., Tanaka, A., Matsushima, T., Kinoshita, M,. Teramoto, T.
(Jimro Co., Ltd., Keio Univ., Tokai Univ., Kagawa Nutrition Univ., Tsukuba Memorial Hospital., Teikyo Univ.)
76th Congress of the European Atherosclerosis Society, June 10-13, 2007, Helsinki, Finland, Poster sessions, PO3-63
# Concentration of Apolipoprotein B48 in Fasting Serum is an Important Marker of Postrandial Hyperlipidemia
Takenaka, H., Kinoshita, H., Maeda, T., Taki, M., Takao, K., Kusano, J., Yoshimura, N., Fujita, M., Teramoto, T.(Teikyo Univ. Sch. Of Med.)
XIV International Symposium on Atherosclerosis, Rome, Italy, June 18-22, 2006 Poster Session, Th-P15:76
# Concentration of apolipoprotein B48 in fasting serum is an important marker of postprandial hyperlipidemia.
Hirota, D., Kinosita, M., Maeda, T., suda, T., Taki, M., Kusano, J., Takenaka, H., Yoshimura,
N., and Teramoto, T.(Teikyo Univ. Sch. of Med. Int. Med.)
The 37th Japan Atherosclerosis Society Annual Meeting, 2005, English session ES-J8,Proceeding p.185
| Page top |
Rat Leptin ELISA KIT(U type) (AKRLP-010)
Original reports
#Rikkunshito and 5-HT2C receptor antagonisit improve cisplatin-induced anorexia via hypothalamic ghrelin interaction
K,Yakabi.,S,Kurosawa.,M,Tamai.,M,Yuzurihara.,M,Nahata.,S,Ohno.,S,Ro.,S,Kato.,T,Aoyama.,T,Sakurada.,
H,Takabayashi., and T,Hattori.
Regulatory Peptides Vol.161,Issues1-3,97-105,2010
# Correlation between Body Weight(Epididymal Fat)and Permeation
Rate of Serum Leptin through the Blood-Brain Barrier(BBB)in
Male Rats Aged 8 Months.
Suzuki, M., Ding,Q., Muranaka,S., Kigure,M., Kojima,M., Terada,M.,
Kataoka,N., Hagiwara,A., Kromkhun,P., Moritani,N., Hashimoto,H.,
Yokosuka,M., Sakurai,F., Tanaka,M. Saito,T.R.
Exp.Anim.57(5),485-488,2008
#Rikkunshito and 5-HT2C receptor antagonisit improve cisplatin-induced anorexia via hypothalamic ghrelin interaction
K,Yakabi.,S,Kurosawa.,M,Tamai.,M,Yuzurihara.,M,Nahata.,S,Ohno.,S,Ro.,S,Kato.,T,Aoyama.,T,Sakurada.,
H,Takabayashi., and T,Hattori.
Regulatory Peptides Vol.161,Issues1-3,97-105,2010
# Correlation between Body Weight(Epididymal Fat)and Permeation
Rate of Serum Leptin through the Blood-Brain Barrier(BBB)in
Male Rats Aged 8 Months.
Suzuki, M., Ding,Q., Muranaka,S., Kigure,M., Kojima,M., Terada,M.,
Kataoka,N., Hagiwara,A., Kromkhun,P., Moritani,N., Hashimoto,H.,
Yokosuka,M., Sakurai,F., Tanaka,M. Saito,T.R.
Exp.Anim.57(5),485-488,2008
| Page top |
Mouse Leptin ELISA KIT(AKRLP-011)
Original reports
#Mate Tea(Ilex paraguariensis)Promotes Satiety and Body Weight Lowering in Mice:Involvement of Glucagon-Like Peptide-1
G, M, E, Hussein., H, Matsuda., S, Nakamura., M, Hamao., T, Akiyama., K, Tamura., and M, Yoshikawa.
Biol.Pharm.Bull.34(12)1849-1855,2011
#Caffeic Acid Phenethyl Ester Suppresses the Production of Adipocytokines,Leptin,Tumor Necrosis Factor-Alpha and Resisitin,during Differentiation to Adipocytes in 3T3-L1 Cells
S,Juman.,N,Yasui.,H,Okuda.,A,Ueda.,H,Negishi.,T,Miki., and K,Ikeda.
Biol.Pharm.Bull.34(4)490-494.2011
Presentations at scientific meetings
#Significance of Circulating Ghrelin (Active and Inactive) in the Progression of
Renal Injury in Diabetes Mellitus and In Non-Smooth Muscle Calponin (Calponin-h2) Transgenic Mice
41st Annual Meeting & Scientific Exposition November 4 - 9, 2008
Pennsylvania Convention Center Philadelphia, Pennsylvania
#Mate Tea(Ilex paraguariensis)Promotes Satiety and Body Weight Lowering in Mice:Involvement of Glucagon-Like Peptide-1
G, M, E, Hussein., H, Matsuda., S, Nakamura., M, Hamao., T, Akiyama., K, Tamura., and M, Yoshikawa.
Biol.Pharm.Bull.34(12)1849-1855,2011
#Caffeic Acid Phenethyl Ester Suppresses the Production of Adipocytokines,Leptin,Tumor Necrosis Factor-Alpha and Resisitin,during Differentiation to Adipocytes in 3T3-L1 Cells
S,Juman.,N,Yasui.,H,Okuda.,A,Ueda.,H,Negishi.,T,Miki., and K,Ikeda.
Biol.Pharm.Bull.34(4)490-494.2011
Presentations at scientific meetings
#Significance of Circulating Ghrelin (Active and Inactive) in the Progression of
Renal Injury in Diabetes Mellitus and In Non-Smooth Muscle Calponin (Calponin-h2) Transgenic Mice
41st Annual Meeting & Scientific Exposition November 4 - 9, 2008
Pennsylvania Convention Center Philadelphia, Pennsylvania
| Page top |
Mouse Resistin ELISA KIT(AKRRS-011)
Original reports
#Antihyperlipidemic and Body Fat-Lowering Effects of Silk Proteins with Different Fibroin/Sericin Compositions in Mice Fed with High Fat Diet
Chung-Won Seo,In Chul Um,Catherine W.Rico,and Mi Young Kang
J.Agric.Food Chem.59,4192-4197,2011
#Dietary Saury Oil Reduces Hyperglycemia and Hyperlipidemia in Diabetic KKAy Mice and in Diet-Induced Obese C57BL/6J Mice by Altering Gene Expression
Z,Yang.,H,Miyahara.,S,Takemura.,A,Hatanaka.
Lipids,46:425-434,2011
#Antihyperlipidemic and Body Fat-Lowering Effects of Silk Proteins with Different Fibroin/Sericin Compositions in Mice Fed with High Fat Diet
Chung-Won Seo,In Chul Um,Catherine W.Rico,and Mi Young Kang
J.Agric.Food Chem.59,4192-4197,2011
#Dietary Saury Oil Reduces Hyperglycemia and Hyperlipidemia in Diabetic KKAy Mice and in Diet-Induced Obese C57BL/6J Mice by Altering Gene Expression
Z,Yang.,H,Miyahara.,S,Takemura.,A,Hatanaka.
Lipids,46:425-434,2011
| Page top |
Mouse TNF a ELISA KIT(AKMTN-011)
Original reports
#The inflammatory changes of adipose tissue in late pregnant mice
L. Zhang., T. Sugiyama., N. Murabayashi., T. Umekawa., N. Ma., Y. Kamimoto., Y. Ogawa. and N. Sagawa.
J Mol Endocrinol, Published online:22 June 2011
#Pitavastatin suppresses diethylnitrosamineinduced liver preneoplasms in male C57BL/KsJdb/db obese mice
M. Shimizu., Y. Yasuda., H. Sakai., M. Kubota., D. Terakura., A. Baba.,T. Ohno., .T. Kochi., H. Tsurumi., T. Tanaka., and H. Moriwaki.
BMC Cancer 2011, 11:281
#Preventive Effects of (-)-Epigallocatechin Gallate on Diethylnitrosamine-Induced Liver Tumorigenesis in Obese and Diabetic C57BL/KsJ-db/db Mice
M. Shimizu., H. Sakai., Y. Shirakami., Y. Yasuda., M. Kubota., D. Terakura., A. Baba., T. Ohno., Y Hara., T. Tanaka., and H. Moriwaki.
Cancer Prev Res; 4(3); 396-403. 2011 AACR
#Antihyperlipidemic and Body Fat-Lowering Effects of Silk Proteins with Different Fibroin/Sericin Compositions in Mice Fed with High Fat Diet
Chung-Won Seo,In Chul Um,Catherine W.Rico,and Mi Young Kang
J.Agric.Food Chem.59,4192-4197,2011
#Dietary Saury Oil Reduces Hyperglycemia and Hyperlipidemia in Diabetic KKAy Mice and in Diet-Induced Obese C57BL/6J Mice by Altering Gene Expression
Z,Yang.,H,Miyahara.,S,Takemura.,A,Hatanaka.
Lipids,46:425-434,2011
#Chicken Collagen Hydrolysate Reduces Proinflammatory Cytokine Production in C57BL/6.KOR-ApoEshl Mice
Zhang,Y.,Kouguchi,T.,Shimizu,K.,Sato,M.,Takahata,Y. and Morimatsu,F.
J Nutr Sci Vitaminol,56,208-210,2010
#Pitavastatin inhibits azoxymethane-induced colonic preneoplastic lesions in C57BL/KsJ-db/db obese mice
Yasuda,Y.,Shimizu,M.,Shirakami,Y.,Sakai,H.,Kubota,M.,Hata,K.,Hirose,Y.,Tsurumi,H.,Tanaka,T.,Morikawa,H.
Cancer Science Vol.101(7),1701-1707,2010
#The inflammatory changes of adipose tissue in late pregnant mice
L. Zhang., T. Sugiyama., N. Murabayashi., T. Umekawa., N. Ma., Y. Kamimoto., Y. Ogawa. and N. Sagawa.
J Mol Endocrinol, Published online:22 June 2011
#Pitavastatin suppresses diethylnitrosamineinduced liver preneoplasms in male C57BL/KsJdb/db obese mice
M. Shimizu., Y. Yasuda., H. Sakai., M. Kubota., D. Terakura., A. Baba.,T. Ohno., .T. Kochi., H. Tsurumi., T. Tanaka., and H. Moriwaki.
BMC Cancer 2011, 11:281
#Preventive Effects of (-)-Epigallocatechin Gallate on Diethylnitrosamine-Induced Liver Tumorigenesis in Obese and Diabetic C57BL/KsJ-db/db Mice
M. Shimizu., H. Sakai., Y. Shirakami., Y. Yasuda., M. Kubota., D. Terakura., A. Baba., T. Ohno., Y Hara., T. Tanaka., and H. Moriwaki.
Cancer Prev Res; 4(3); 396-403. 2011 AACR
#Antihyperlipidemic and Body Fat-Lowering Effects of Silk Proteins with Different Fibroin/Sericin Compositions in Mice Fed with High Fat Diet
Chung-Won Seo,In Chul Um,Catherine W.Rico,and Mi Young Kang
J.Agric.Food Chem.59,4192-4197,2011
#Dietary Saury Oil Reduces Hyperglycemia and Hyperlipidemia in Diabetic KKAy Mice and in Diet-Induced Obese C57BL/6J Mice by Altering Gene Expression
Z,Yang.,H,Miyahara.,S,Takemura.,A,Hatanaka.
Lipids,46:425-434,2011
#Chicken Collagen Hydrolysate Reduces Proinflammatory Cytokine Production in C57BL/6.KOR-ApoEshl Mice
Zhang,Y.,Kouguchi,T.,Shimizu,K.,Sato,M.,Takahata,Y. and Morimatsu,F.
J Nutr Sci Vitaminol,56,208-210,2010
#Pitavastatin inhibits azoxymethane-induced colonic preneoplastic lesions in C57BL/KsJ-db/db obese mice
Yasuda,Y.,Shimizu,M.,Shirakami,Y.,Sakai,H.,Kubota,M.,Hata,K.,Hirose,Y.,Tsurumi,H.,Tanaka,T.,Morikawa,H.
Cancer Science Vol.101(7),1701-1707,2010
| Page top |
Mouse/Rat High Molecular Weight Adiponectin ELISA KIT(AKMAN-011)
Original reports
#A Comparative Study of Gastric Banding and Sleeve Gastrectomy in an Obese Diabetic Rat Model
T. Masuda., M. Ohta., T. Hirashita., Y. Kawano., H. Egucji., K. Yada., Y. Iwashita., S. Kitano
Obesity Surgery, Published online:27 August 2011
#Anti-Diabetic Effects of a Kaempferol Glycoside-Rich Fraction from Unripe Soybean (Edamame,Glycine max L.Merrill.'Jindai') Leaves on KK-Ay Mice
Y. Zang., H. Sato., K. Igarashi.
Biosci.Biotechnol.Biochem,75(9),1677-1684,2011
#Effects of visceral fat resection and gastric banding in an obese diabetic rat model
T. Hirashita., M. Ohta., Y. Endo., T. Masuda., Y. Iwashita., S. Kitano
Surgery,In Press ,2011
#Preventive Effects of Curcumin on the Development of Azoxymethane-Induced Colonic Preneoplastic Lesions in Male C57BL/KsJ-db/db Obese Mice
M. Kubota., M. Shimizu., H. Sakai., Y. Yasuda., D. Terakura., A. Baba., T. Ohno., H. Tsurumi., T. Tanaka., H. Moriwaki.
Nutrition and Cancer ,Published online:15 Dec 2011
#Exercise training intensity/volume affects plasma and tissue adeiponectin concentration in the male rat
Elahe Talebi Garekani,Hamid Mohebbi,Robert R.Kraemer,Rozita Fathi
Peptides Vol.32(5) May 2011,1008-1012
#Antihyperlipidemic and Body Fat-Lowering Effects of Silk Proteins with Different Fibroin/Sericin Compositions in Mice Fed with High Fat Diet
Chung-Won Seo,In Chul Um,Catherine W.Rico,and Mi Young Kang
J.Agric.Food Chem.59,4192-4197,2011
#Trehalose prevents adipocyte hypertrophy and mitigates insulin resistance
C,Arai.,N,Arai.,A,Mizote.,K,Kohno.,K,Iwaki.,T,Hanaya.,S,Arai.,S,Ushio.,S,Fukuda.
Nutrition Research Vol.30,Issue12,840-848,2010
#Combined Effects of Short-term Calorie Restriction and Exercise on Insulin Action in Normal Rats
H,Y,Jiang.,T,Koike.,P,Li.,Z,H,Wang.,Y,Kawata.,Y,Oshida.
Horm Metab Res 2010; 42(13): 950-954
#Dietary Hesperidin Exerts Hypoglycemic and Hypolipidemic Effects in Streptozocin-Induce Marginal Type 1 Diabetic Rats
Akiyama,S., Katsumata,S., Suzuki,K., Ishimi,Y.,Wu,J., and Uehara,M.
J Clin Biochem Nutr.January;46(1):87-92.2010
#Hypoglycemic and Hypolipidemic Effects of Hesperidin and Cyclodextrin-Clathrated Hesperetin in Goto-Kakizaki Rats with Type 2 Diabetes
Akiyama,S., Katsumata,S., Suzuki,K., Nakayama,Y., Ishimi,Y. and Uehara,M.
Bioscience,Biotechnology,and Biochemistry.Vol.73,No.12 pp.2779-2782(2009)
#A Comparative Study of Gastric Banding and Sleeve Gastrectomy in an Obese Diabetic Rat Model
T. Masuda., M. Ohta., T. Hirashita., Y. Kawano., H. Egucji., K. Yada., Y. Iwashita., S. Kitano
Obesity Surgery, Published online:27 August 2011
#Anti-Diabetic Effects of a Kaempferol Glycoside-Rich Fraction from Unripe Soybean (Edamame,Glycine max L.Merrill.'Jindai') Leaves on KK-Ay Mice
Y. Zang., H. Sato., K. Igarashi.
Biosci.Biotechnol.Biochem,75(9),1677-1684,2011
#Effects of visceral fat resection and gastric banding in an obese diabetic rat model
T. Hirashita., M. Ohta., Y. Endo., T. Masuda., Y. Iwashita., S. Kitano
Surgery,In Press ,2011
#Preventive Effects of Curcumin on the Development of Azoxymethane-Induced Colonic Preneoplastic Lesions in Male C57BL/KsJ-db/db Obese Mice
M. Kubota., M. Shimizu., H. Sakai., Y. Yasuda., D. Terakura., A. Baba., T. Ohno., H. Tsurumi., T. Tanaka., H. Moriwaki.
Nutrition and Cancer ,Published online:15 Dec 2011
#Exercise training intensity/volume affects plasma and tissue adeiponectin concentration in the male rat
Elahe Talebi Garekani,Hamid Mohebbi,Robert R.Kraemer,Rozita Fathi
Peptides Vol.32(5) May 2011,1008-1012
#Antihyperlipidemic and Body Fat-Lowering Effects of Silk Proteins with Different Fibroin/Sericin Compositions in Mice Fed with High Fat Diet
Chung-Won Seo,In Chul Um,Catherine W.Rico,and Mi Young Kang
J.Agric.Food Chem.59,4192-4197,2011
#Trehalose prevents adipocyte hypertrophy and mitigates insulin resistance
C,Arai.,N,Arai.,A,Mizote.,K,Kohno.,K,Iwaki.,T,Hanaya.,S,Arai.,S,Ushio.,S,Fukuda.
Nutrition Research Vol.30,Issue12,840-848,2010
#Combined Effects of Short-term Calorie Restriction and Exercise on Insulin Action in Normal Rats
H,Y,Jiang.,T,Koike.,P,Li.,Z,H,Wang.,Y,Kawata.,Y,Oshida.
Horm Metab Res 2010; 42(13): 950-954
#Dietary Hesperidin Exerts Hypoglycemic and Hypolipidemic Effects in Streptozocin-Induce Marginal Type 1 Diabetic Rats
Akiyama,S., Katsumata,S., Suzuki,K., Ishimi,Y.,Wu,J., and Uehara,M.
J Clin Biochem Nutr.January;46(1):87-92.2010
#Hypoglycemic and Hypolipidemic Effects of Hesperidin and Cyclodextrin-Clathrated Hesperetin in Goto-Kakizaki Rats with Type 2 Diabetes
Akiyama,S., Katsumata,S., Suzuki,K., Nakayama,Y., Ishimi,Y. and Uehara,M.
Bioscience,Biotechnology,and Biochemistry.Vol.73,No.12 pp.2779-2782(2009)
| Page top |
Mouse Anti-dsDNA antibody ELISA kit (AKRDD-061)
Original reports
#Eradication of Metastatic Renal Cell Carcinoma after Adenovirus-Encoded TNF-Related Apoptosis-Inducing Ligand (TRAIL)/CpG Immunotherapy
L. A. Norian., T. P. Kresowik., H. M. Rosevear., B. R. James., T. R. Rosean., A. J. Lightfoot., T. A. Kucaba., C. Schwarz., C. J. Weydert., M. D. Henry., T. S. Griffith.
PLos One 7(2):e31085. 2012
#Reversal of serologic, immunologic, and histologic dysfunction in mice with systemic lupus erythematosus by long-term serial adipose tissue?derived mesenchymal stem cell transplantation
E.W. Choi., Il S. Shin., S. Y. Park., J. H. Park., J. S. Kim., E. J. Yoon., S. K. Kang., J. C. Ra., S. H. Hong.
Arthritis & Rheumatism Vol. 64, Issue 1, pages 243-253, 2012
#Serum soluble MD-1 levels increase with disease progression in autoimmune prone MRLlpr/lpr mice
S. Sasakia., Y. Nagaia., T. Yanagibashia., Y. Watanabea., M. Ikutania., A. Kariyonea., K. Tsuneyamab., Y. Hiraia., K. Takatsua.
Molecular Immunology Vol.49,Issue4,611-620, 2012
#Deamidation of Gliadin Peptides in Lamina Propria: Implications for Celiac Disease
H. Skovbjerg., D. Anthonsen., E. Knudsen. and H. Sjostrom.
J of Clinical Immunology Vol.31 ( 6) 1038-1044 , 2011
#Transgenic Mice that Overexpress Human IL-15 in Enterocytes Recapitulate Both B and T Cell-Mediated Pathologic Manifestations of Celiac Disease
S. Yokoyama., K. Takada., M. Hirasawa., L. P. Perera., and T. Hiroi.
J of Clinical Immunology Vol. 31,(6) , 2011
#Coincidence of autoantibody production with the activation of natural killer T cells in a-galactosylceramide-mediated hepatic injury
H. Matsumoto., T. Kawamura., T. Kobayashi., Y. Kanda., H. Kawamura., T. Abo.
Immunology Vol. 133, Issue 1, pages 21-28, 2011
#Lack of B and T lymphocyte attenuator exacerbates autoimmune disorders and induces Fas-independent liver injury in MRL-lpr/lpr mice
Y. Oya., N. Watanabe. Y. Kobayashi., T. Owada., M. Oki., K. Ikeda. A. Suto., S. Kagami., K. Hirose., T. Kishimoto., and H. Nakajima.
Int. Immunol 23 (5): 335-344, 2011
#Amelioration of systemic lupus erythematosus by withangulatin A in MRL/lpr mice
L. Sun., L. Zhou., M. Chen., R. Zhong., J. Liu.
Journal of Cellular Biochemistry Vol. 112, Issue 9, pages 2376-2382, 2011
#Co-appearance of autoantibody-producing B220low B cells with NKT cells in the course of hepatic injury
Y. Fujii., H. Kawamura., T. Kawamura., Y. Kanda.,H. Matsumoto., T. Kobayashi., T. Yamamoto., T. Aoyama., T. Abo.
Cellular Immunology Vol.260,Issue2, 105-112, 2010
#Identification and characterization of autoantibody-producing B220low B (B-1) cells appearing in malarial infection
Y. Kanda., H. Kawamura., H. Matsumoto., T. Kobayashi., T. Kawamura., T. Abo.
Cellular Immunology Vol.263,Issue1, 49-54, 2010
#Transplantation of umbilical cord mesenchymal stem cells alleviates lupus nephritis in MRL/lpr mice
Z. Gu., K. Akiyama., X. Ma., H. Zhang., X. Feng., G. Yao., Y. Hou., L. Lu., GS. Gilkeson., RM. Silver., X. Zeng., S. Shi., L. Sun
Lupus Vol.19 No.13, 1502-1514, 2010
#Augmented TLR9-induced Btk activation in PIR-B?deficient B-1 cells provokes excessive autoantibody production and autoimmunity
T. Kubo., Y. Uchida., Y. Watanabe., M. Abe., A. Nakamura., M. Ono., S. Akira., and T. Takai.
J of Experimental Medicine Vol.206 No.9 1971-1982, 2009
#Deficiency in EBV-induced gene 3 (EBI3) in MRL/ lpr mice results in pathological alteration of autoimmune glomerulonephritis and sialadenitis
T. Igawa., H. Nakashima., A. Sadanaga., K. Masutani., K. Miyake., S. Shimizu., A. Takeda., S. Hamano., and H. Yoshida.
Modern Rheumatology Vol. 19, Number 1, 33-41, 2009
#Oncostatin M deficiency leads to thymic hypoplasia, accumulation of apoptotic thymocytes and glomerulonephritis
E. Esashi1., H. Ito., K. Minehata., S. Saito., Y. Morikawa., A. Miyajima.
European Journal of Immunology Vol.39,Issue6, 1664-1670, 2009
#Amelioration of human lupus-like phenotypes in MRL/lpr mice by overexpression of interleukin 27 receptor a (WSX-1)
N. Sugiyama., H. Nakashima., T. Yoshimura., A. Sadanaga., S. Shimizu., K. Masutani., T. Igawa., M. Akahoshi., K. Miyake., A. Takeda., A. Yoshimura., S. Hamano., H. Yoshida.
Ann Rheum Dis 67:1461-1467, 2008
#Development of autoantibody responses in NC/Nga mice: its prevention by pulverized konjac glucomannan feeding
N. Onishi., S. Kawamoto., H. Suzuki., M. Hide., and K. Ono.
Archives of Dermatological Research Vol.300, 95-99, 2008
#CD19 Regulates Skin and Lung Fibrosis via Toll-Like Receptor Signaling in a Model of Bleomycin-Induced Scleroderma
A. Yoshizaki., Y. Iwata., K. Komura., F. Ogawa., T. Hara., E. Muroi., M. Takenaka., K. Shimizu., M. Hasegawa., M. Fujimoto., T. F. Tedder., and S. Sato.
Am J Pathol. 172(6): 1650-1663, 2008
#Protection against autoimmune nephritis in MyD88-deficient MRL/lpr mice
A. Sadanaga., H. Nakashima., M. Akahoshi., K. Masutani., K. Miyake., T. Igawa., N. Sugiyama., H. Niiro., M. Harada.
Arthritis & Rheumatism Vol.56, Issue 5, pages 1618-1628, 2007
# Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages.
Kawane, K., Ohtani, M., Miwa, K., Kizawa, T., Kanbara, Y., Yoshioka, Y., and Yoshikawa, H.
Nature 443: 998-1002, 2006
#Altered cytokine expression in mesenteric lymph nodes in a rat strain (Matsumoto Eosinophilic Shinshu) that spontaneously develops hypereosinophilia
S. Muto., M. Monnai., Y. Okuhara., M. Murakami., J. Kuroda., T. Ono., K. Matsumoto.
Immunology Vol. 116, Issue 3, pages 373-380, 2005
# Amelioration of autoimmune nephritis by imatinib in MRL/lpr mice
Sadanaga, A., Nakashima, H., Masutani, K., Miyake, K., shimizu, S., Igawa, T., Sugiyama, N., Niiro, H., Hirakata, H., and Harada, M.
Arthritis Rheumatism 52: 3987-3996, 2005
# Membranous glomerulonephritis development with Th2-type immune deviations in MRL/lpr mice deficient for IL-27 receptor (WSX-1)
Shimizu, S., Sugiyama, N., Matsutani, K., Sadanaga, A., Miyazaki, Y., Inoue, Y., Akaboshi, M., Katafuchi, R., Hirakata, H., Harada. M., Hamano, S., Nakashima, H., and Yoshida, H.
J Immunol 175:7185-7192, 2005
# Glucose intolerance in young TallyHo mice is induced by leptin-mediated inhibition of insulin.
Sung, Y.Y., Lee, Y.S., Jung, W.H., Kim, H.Y., Cheon, H.G., Yang, S.D., and Rhee, S.D.
Biochem Biopys Res Commun. 338: 1779-1787, 2005
# Requirement for CD100-CD72 interactions in fine-tubing of B-cell antigen receptor signaling and homeostatic maintenance ofthe B-cell compartment.
Kumanogoh, A., Shikina, T., Watanabe, C., Takegahara, N., Suzuki, K., Yamamoto, M., Takamatsu, H., Prasad, D.V.R., Mizui, M., Toyohuku, T., Tamaru, M., Watanabe, D., Parnes, J.R., and Kikutani, H.
International Immuno, 17: 1277-1282, 2005
# Chemical induction of HO-1 suppresses lupus nephritis by reducing local iNOS expression and synthesis of anti-dsDNA antibody.
Takeda, Y., Takeno, M., Iwasaki, M., Kobayashi, H., Kirino, Y., Ueda, A., Nagahama, K., Aoki, I., and Ishigatsubo, Y
Clin Exp Immunol. 138:237-244, 2004
# The point mutation of tyrosine 759 of the IL-6 family cytokine receptor gp130 synergizes with HTLV-1 pX in promoting rheumatoid arthritis-like arthritis.
Ishihara, K., Sawa, S., Ikushima, H., Hirota, S., Atsumi, T., Kamimura, D., Park, S.J., Murakami, M., Kitanuma, Y., Iwakura, Y., and Hirano, T.
International Immunol. 16: 455-465, 2004
# Inadequate induction of suppressor of cytokine signaling-1 causes systemic autoimmune disease
Fujimoto, M., Tsutsui, H., Xinshou, O., Tokumoto, M., Watanabe, D., Shima, Y., Yoshimoto, T., Hirakata, H., Kawase, I., Nakanishi, K., Kishimoto, T., and Naka, T.
International Immunol. 16: 303-314, 2004
# Suppressor of cytokine signaling-1 is essential for suppressing dendritic cell activation and systemic autoimmunity.
Hanada, T., Yoshida, H., Kato, S., Tanaka, K., Matsutani, K., Tsukada, J., Nomura, Y., Mimata, H., Kubo, M., and Yoshimura, A.
Immunity: 19: 437-450, 2003
# Association of Cathepsin E Deficiency with Development of Atopic Dermatitis
Tsukuba et al.
J Biochem (Tokyo). 134: 893-902, 2003
# Fc RIIB deficiency with Fas mutation is sufficient for the development of systemic autoimmune disease.
Yajima, K., Nakamura, A., Sugahara, A., and Takai, T.
Eur J Immunol, 33:(4) 1020-1029, 2003
# A Point Mutation of Tyr-759 in Interleukin 6 Family Cytokine Receptor Subunit gp130 Causes Autoimmune Arthritis
T. Atsumi., K. Ishihara., D. Kamimura., H. Ikushima., T. Ohtani., S. Hirota., H. Kobayashi., S. Park., Y. Saeki., Y. Kitamura. and T. Hirano
J Exp Med, 196, Number 7, 979-990, 2002
# A novel assay kits for autoantibodies rate on spontaneous autoimmune model mice.
Kikukawa, T, Kojima, M., and Abe, C.
Jap J Inflammation 20: 697-701, 2000
#Eradication of Metastatic Renal Cell Carcinoma after Adenovirus-Encoded TNF-Related Apoptosis-Inducing Ligand (TRAIL)/CpG Immunotherapy
L. A. Norian., T. P. Kresowik., H. M. Rosevear., B. R. James., T. R. Rosean., A. J. Lightfoot., T. A. Kucaba., C. Schwarz., C. J. Weydert., M. D. Henry., T. S. Griffith.
PLos One 7(2):e31085. 2012
#Reversal of serologic, immunologic, and histologic dysfunction in mice with systemic lupus erythematosus by long-term serial adipose tissue?derived mesenchymal stem cell transplantation
E.W. Choi., Il S. Shin., S. Y. Park., J. H. Park., J. S. Kim., E. J. Yoon., S. K. Kang., J. C. Ra., S. H. Hong.
Arthritis & Rheumatism Vol. 64, Issue 1, pages 243-253, 2012
#Serum soluble MD-1 levels increase with disease progression in autoimmune prone MRLlpr/lpr mice
S. Sasakia., Y. Nagaia., T. Yanagibashia., Y. Watanabea., M. Ikutania., A. Kariyonea., K. Tsuneyamab., Y. Hiraia., K. Takatsua.
Molecular Immunology Vol.49,Issue4,611-620, 2012
#Deamidation of Gliadin Peptides in Lamina Propria: Implications for Celiac Disease
H. Skovbjerg., D. Anthonsen., E. Knudsen. and H. Sjostrom.
J of Clinical Immunology Vol.31 ( 6) 1038-1044 , 2011
#Transgenic Mice that Overexpress Human IL-15 in Enterocytes Recapitulate Both B and T Cell-Mediated Pathologic Manifestations of Celiac Disease
S. Yokoyama., K. Takada., M. Hirasawa., L. P. Perera., and T. Hiroi.
J of Clinical Immunology Vol. 31,(6) , 2011
#Coincidence of autoantibody production with the activation of natural killer T cells in a-galactosylceramide-mediated hepatic injury
H. Matsumoto., T. Kawamura., T. Kobayashi., Y. Kanda., H. Kawamura., T. Abo.
Immunology Vol. 133, Issue 1, pages 21-28, 2011
#Lack of B and T lymphocyte attenuator exacerbates autoimmune disorders and induces Fas-independent liver injury in MRL-lpr/lpr mice
Y. Oya., N. Watanabe. Y. Kobayashi., T. Owada., M. Oki., K. Ikeda. A. Suto., S. Kagami., K. Hirose., T. Kishimoto., and H. Nakajima.
Int. Immunol 23 (5): 335-344, 2011
#Amelioration of systemic lupus erythematosus by withangulatin A in MRL/lpr mice
L. Sun., L. Zhou., M. Chen., R. Zhong., J. Liu.
Journal of Cellular Biochemistry Vol. 112, Issue 9, pages 2376-2382, 2011
#Co-appearance of autoantibody-producing B220low B cells with NKT cells in the course of hepatic injury
Y. Fujii., H. Kawamura., T. Kawamura., Y. Kanda.,H. Matsumoto., T. Kobayashi., T. Yamamoto., T. Aoyama., T. Abo.
Cellular Immunology Vol.260,Issue2, 105-112, 2010
#Identification and characterization of autoantibody-producing B220low B (B-1) cells appearing in malarial infection
Y. Kanda., H. Kawamura., H. Matsumoto., T. Kobayashi., T. Kawamura., T. Abo.
Cellular Immunology Vol.263,Issue1, 49-54, 2010
#Transplantation of umbilical cord mesenchymal stem cells alleviates lupus nephritis in MRL/lpr mice
Z. Gu., K. Akiyama., X. Ma., H. Zhang., X. Feng., G. Yao., Y. Hou., L. Lu., GS. Gilkeson., RM. Silver., X. Zeng., S. Shi., L. Sun
Lupus Vol.19 No.13, 1502-1514, 2010
#Augmented TLR9-induced Btk activation in PIR-B?deficient B-1 cells provokes excessive autoantibody production and autoimmunity
T. Kubo., Y. Uchida., Y. Watanabe., M. Abe., A. Nakamura., M. Ono., S. Akira., and T. Takai.
J of Experimental Medicine Vol.206 No.9 1971-1982, 2009
#Deficiency in EBV-induced gene 3 (EBI3) in MRL/ lpr mice results in pathological alteration of autoimmune glomerulonephritis and sialadenitis
T. Igawa., H. Nakashima., A. Sadanaga., K. Masutani., K. Miyake., S. Shimizu., A. Takeda., S. Hamano., and H. Yoshida.
Modern Rheumatology Vol. 19, Number 1, 33-41, 2009
#Oncostatin M deficiency leads to thymic hypoplasia, accumulation of apoptotic thymocytes and glomerulonephritis
E. Esashi1., H. Ito., K. Minehata., S. Saito., Y. Morikawa., A. Miyajima.
European Journal of Immunology Vol.39,Issue6, 1664-1670, 2009
#Amelioration of human lupus-like phenotypes in MRL/lpr mice by overexpression of interleukin 27 receptor a (WSX-1)
N. Sugiyama., H. Nakashima., T. Yoshimura., A. Sadanaga., S. Shimizu., K. Masutani., T. Igawa., M. Akahoshi., K. Miyake., A. Takeda., A. Yoshimura., S. Hamano., H. Yoshida.
Ann Rheum Dis 67:1461-1467, 2008
#Development of autoantibody responses in NC/Nga mice: its prevention by pulverized konjac glucomannan feeding
N. Onishi., S. Kawamoto., H. Suzuki., M. Hide., and K. Ono.
Archives of Dermatological Research Vol.300, 95-99, 2008
#CD19 Regulates Skin and Lung Fibrosis via Toll-Like Receptor Signaling in a Model of Bleomycin-Induced Scleroderma
A. Yoshizaki., Y. Iwata., K. Komura., F. Ogawa., T. Hara., E. Muroi., M. Takenaka., K. Shimizu., M. Hasegawa., M. Fujimoto., T. F. Tedder., and S. Sato.
Am J Pathol. 172(6): 1650-1663, 2008
#Protection against autoimmune nephritis in MyD88-deficient MRL/lpr mice
A. Sadanaga., H. Nakashima., M. Akahoshi., K. Masutani., K. Miyake., T. Igawa., N. Sugiyama., H. Niiro., M. Harada.
Arthritis & Rheumatism Vol.56, Issue 5, pages 1618-1628, 2007
# Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages.
Kawane, K., Ohtani, M., Miwa, K., Kizawa, T., Kanbara, Y., Yoshioka, Y., and Yoshikawa, H.
Nature 443: 998-1002, 2006
#Altered cytokine expression in mesenteric lymph nodes in a rat strain (Matsumoto Eosinophilic Shinshu) that spontaneously develops hypereosinophilia
S. Muto., M. Monnai., Y. Okuhara., M. Murakami., J. Kuroda., T. Ono., K. Matsumoto.
Immunology Vol. 116, Issue 3, pages 373-380, 2005
# Amelioration of autoimmune nephritis by imatinib in MRL/lpr mice
Sadanaga, A., Nakashima, H., Masutani, K., Miyake, K., shimizu, S., Igawa, T., Sugiyama, N., Niiro, H., Hirakata, H., and Harada, M.
Arthritis Rheumatism 52: 3987-3996, 2005
# Membranous glomerulonephritis development with Th2-type immune deviations in MRL/lpr mice deficient for IL-27 receptor (WSX-1)
Shimizu, S., Sugiyama, N., Matsutani, K., Sadanaga, A., Miyazaki, Y., Inoue, Y., Akaboshi, M., Katafuchi, R., Hirakata, H., Harada. M., Hamano, S., Nakashima, H., and Yoshida, H.
J Immunol 175:7185-7192, 2005
# Glucose intolerance in young TallyHo mice is induced by leptin-mediated inhibition of insulin.
Sung, Y.Y., Lee, Y.S., Jung, W.H., Kim, H.Y., Cheon, H.G., Yang, S.D., and Rhee, S.D.
Biochem Biopys Res Commun. 338: 1779-1787, 2005
# Requirement for CD100-CD72 interactions in fine-tubing of B-cell antigen receptor signaling and homeostatic maintenance ofthe B-cell compartment.
Kumanogoh, A., Shikina, T., Watanabe, C., Takegahara, N., Suzuki, K., Yamamoto, M., Takamatsu, H., Prasad, D.V.R., Mizui, M., Toyohuku, T., Tamaru, M., Watanabe, D., Parnes, J.R., and Kikutani, H.
International Immuno, 17: 1277-1282, 2005
# Chemical induction of HO-1 suppresses lupus nephritis by reducing local iNOS expression and synthesis of anti-dsDNA antibody.
Takeda, Y., Takeno, M., Iwasaki, M., Kobayashi, H., Kirino, Y., Ueda, A., Nagahama, K., Aoki, I., and Ishigatsubo, Y
Clin Exp Immunol. 138:237-244, 2004
# The point mutation of tyrosine 759 of the IL-6 family cytokine receptor gp130 synergizes with HTLV-1 pX in promoting rheumatoid arthritis-like arthritis.
Ishihara, K., Sawa, S., Ikushima, H., Hirota, S., Atsumi, T., Kamimura, D., Park, S.J., Murakami, M., Kitanuma, Y., Iwakura, Y., and Hirano, T.
International Immunol. 16: 455-465, 2004
# Inadequate induction of suppressor of cytokine signaling-1 causes systemic autoimmune disease
Fujimoto, M., Tsutsui, H., Xinshou, O., Tokumoto, M., Watanabe, D., Shima, Y., Yoshimoto, T., Hirakata, H., Kawase, I., Nakanishi, K., Kishimoto, T., and Naka, T.
International Immunol. 16: 303-314, 2004
# Suppressor of cytokine signaling-1 is essential for suppressing dendritic cell activation and systemic autoimmunity.
Hanada, T., Yoshida, H., Kato, S., Tanaka, K., Matsutani, K., Tsukada, J., Nomura, Y., Mimata, H., Kubo, M., and Yoshimura, A.
Immunity: 19: 437-450, 2003
# Association of Cathepsin E Deficiency with Development of Atopic Dermatitis
Tsukuba et al.
J Biochem (Tokyo). 134: 893-902, 2003
# Fc RIIB deficiency with Fas mutation is sufficient for the development of systemic autoimmune disease.
Yajima, K., Nakamura, A., Sugahara, A., and Takai, T.
Eur J Immunol, 33:(4) 1020-1029, 2003
# A Point Mutation of Tyr-759 in Interleukin 6 Family Cytokine Receptor Subunit gp130 Causes Autoimmune Arthritis
T. Atsumi., K. Ishihara., D. Kamimura., H. Ikushima., T. Ohtani., S. Hirota., H. Kobayashi., S. Park., Y. Saeki., Y. Kitamura. and T. Hirano
J Exp Med, 196, Number 7, 979-990, 2002
# A novel assay kits for autoantibodies rate on spontaneous autoimmune model mice.
Kikukawa, T, Kojima, M., and Abe, C.
Jap J Inflammation 20: 697-701, 2000
| Page top |
Mouse Anti-ssDNA antibody ELISA kit (AKRSD-051)
Original reports
# Point mutation of tyrosine 759 of the IL-6 family cytokine receptor,gp130,augments collagen-induced arthritis in DBA/IJ mice
Tsuji,F.,Yoshimi,M.,Katsuta,O.,Takai,M.,Ishihara,K.,Aono,H.
BMC Musculoskeletal Disorders, 10:23, 2009
#Augmented TLR9-induced Btk activation in PIR-B?deficient B-1 cells provokes excessive autoantibody production and autoimmunity
T. Kubo., Y. Uchida., Y. Watanabe., M. Abe., A. Nakamura., M. Ono., S. Akira., and T. Takai.
J of Experimental Medicine Vol.206 No.9 1971-1982, 2009
# CD19 Regulates Skin and Lung Fibrosis via Toll-Like Receptor Signaling in a Model of Bleomycin-Induced Scleroderma.
Yoshizaki,A., Iwata,Y., Komura,K., Ogawa,F., Hara,T., Muroi,E., Takenaka,M., Shimizu,K., Hasegawa,M., Fujimoto,M., Tedder,T.F., and Sato, S.
American Journal of Pathology, 172, pp.1650-1663, 2008
#Altered cytokine expression in mesenteric lymph nodes in a rat strain (Matsumoto Eosinophilic Shinshu) that spontaneously develops hypereosinophilia
S. Muto., M. Monnai., Y. Okuhara., M. Murakami., J. Kuroda., T. Ono., K. Matsumoto.
Immunology Vol. 116, Issue 3, pages 373-380, 2005
# Requirement for CD100-CD72 interactions in fine-tuning of B-cell antigen receptor signaling and homeostatic maintenance of the B-cell compartment.
Kumanogoh, A., Shikina, T., Watanabe, C., Takegahara, N., Suzuki, K., Yamamoto, M., Takamatsu, H., Prasad, D.V.R., Mizui, M., Toyohuku, T., Tamaru, M., Watanabe, D., Parnes, J.R., and Kikutani, H.
International Immuno, 17: 1277-1282, 2005
# Inadequate induction of suppressor of cytokine signaling-1 causes systemic autoimmune disease
Fujimoto, M., Tsutsui, H., Xinshou, O., Tokumoto, M., Watanabe, D., Shima, Y., Yoshimoto, T., Hirakata, H., Kawase, I., Nakanishi, K., Kishimoto, T., and Naka, T.
International Immunol. 16: 303-314, 2004
# Fc RIIB deficiency with Fas mutation is sufficient for the development of systemic autoimmune disease.
Yajima, K., Nakamura, A., Sugahara, A., and Takai, T.
Eur J Immunol, 33:(4) 1020-1029, 2003
# A Point Mutation of Tyr-759 in Interleukin 6 Family Cytokine Receptor Subunit gp130 Causes Autoimmune Arthritis
T. Atsumi., K. Ishihara., D. Kamimura., H. Ikushima., T. Ohtani., S. Hirota., H. Kobayashi., S. Park., Y. Saeki., Y. Kitamura. and T. Hirano
J Exp Med, 196, Number 7, 979-990, 2002
# A novel assay kits for autoantibodies rate on spontaneous autoimmune model mice.
Kikukawa, T, Kojima, M., and Abe, C.
Jap J Inflammation 20: 697-701, 2000
# Point mutation of tyrosine 759 of the IL-6 family cytokine receptor,gp130,augments collagen-induced arthritis in DBA/IJ mice
Tsuji,F.,Yoshimi,M.,Katsuta,O.,Takai,M.,Ishihara,K.,Aono,H.
BMC Musculoskeletal Disorders, 10:23, 2009
#Augmented TLR9-induced Btk activation in PIR-B?deficient B-1 cells provokes excessive autoantibody production and autoimmunity
T. Kubo., Y. Uchida., Y. Watanabe., M. Abe., A. Nakamura., M. Ono., S. Akira., and T. Takai.
J of Experimental Medicine Vol.206 No.9 1971-1982, 2009
# CD19 Regulates Skin and Lung Fibrosis via Toll-Like Receptor Signaling in a Model of Bleomycin-Induced Scleroderma.
Yoshizaki,A., Iwata,Y., Komura,K., Ogawa,F., Hara,T., Muroi,E., Takenaka,M., Shimizu,K., Hasegawa,M., Fujimoto,M., Tedder,T.F., and Sato, S.
American Journal of Pathology, 172, pp.1650-1663, 2008
#Altered cytokine expression in mesenteric lymph nodes in a rat strain (Matsumoto Eosinophilic Shinshu) that spontaneously develops hypereosinophilia
S. Muto., M. Monnai., Y. Okuhara., M. Murakami., J. Kuroda., T. Ono., K. Matsumoto.
Immunology Vol. 116, Issue 3, pages 373-380, 2005
# Requirement for CD100-CD72 interactions in fine-tuning of B-cell antigen receptor signaling and homeostatic maintenance of the B-cell compartment.
Kumanogoh, A., Shikina, T., Watanabe, C., Takegahara, N., Suzuki, K., Yamamoto, M., Takamatsu, H., Prasad, D.V.R., Mizui, M., Toyohuku, T., Tamaru, M., Watanabe, D., Parnes, J.R., and Kikutani, H.
International Immuno, 17: 1277-1282, 2005
# Inadequate induction of suppressor of cytokine signaling-1 causes systemic autoimmune disease
Fujimoto, M., Tsutsui, H., Xinshou, O., Tokumoto, M., Watanabe, D., Shima, Y., Yoshimoto, T., Hirakata, H., Kawase, I., Nakanishi, K., Kishimoto, T., and Naka, T.
International Immunol. 16: 303-314, 2004
# Fc RIIB deficiency with Fas mutation is sufficient for the development of systemic autoimmune disease.
Yajima, K., Nakamura, A., Sugahara, A., and Takai, T.
Eur J Immunol, 33:(4) 1020-1029, 2003
# A Point Mutation of Tyr-759 in Interleukin 6 Family Cytokine Receptor Subunit gp130 Causes Autoimmune Arthritis
T. Atsumi., K. Ishihara., D. Kamimura., H. Ikushima., T. Ohtani., S. Hirota., H. Kobayashi., S. Park., Y. Saeki., Y. Kitamura. and T. Hirano
J Exp Med, 196, Number 7, 979-990, 2002
# A novel assay kits for autoantibodies rate on spontaneous autoimmune model mice.
Kikukawa, T, Kojima, M., and Abe, C.
Jap J Inflammation 20: 697-701, 2000
| Page top |
Mouse Rheumatoid Factor IgG Type ELISA Kit (AKRRG-101)
Original reports
# Increased expression of soluble form of vascular cell adhesion molecule-1 aggravates autoimmune arthritis in MRL-Fasipr mice.
Oishi, H., Mizuki, S., Terada, M., Kudo, M., Araki, K., Araki, M., Nose, M., and Takahashi, S.
Pathology International 57: 734-740, 2007
# Electro-acupuncture at acupoint ST36 reduces inflammation and regulates immune activity in collagen-induced arthritic mice.
Yim, Y.Y., Lee, H., Hong, K.E., Kim, Y.I., Lee, B.R., Son, C.G., and Kim, J.E.
Evidence-based Complementary and Alternative Medicine 4:51-57, 2007
# Requirement for CD100-CD72 interactions in fine-tuning of B-cell antigen receptor signaling and homeostatic maintenance of the B-cell compartment.
Kumanogoh, A., Shikina, T., Watanabe, C., Takegahara, N., Suzuki, K., Yamamoto, M., Takamatsu, H., Prasad, D.V.R., Mizui, M., Toyohuku, T., Tamaru, M., Watanabe, D., Parnes, J.R., and Kikutani, H.
International Immuno, 17: 1277-1282, 2005
# The point mutation of tyrosine 759 of the IL-6 family cytokine receptor gp130 synergizes with HTLV-1 pX in promoting rheumatoid arthritis-like arthritis.
Ishihara, K., Sawa, S., Ikushima, H., Hirota, S., Atsumi, T., Kamimura, D., Park, S.J., Murakami, M., Kitanuma, Y., Iwakura, Y., and Hirano, T.
International Immunol. 16: 455-465, 2004
# Chemical induction of HO-1 suppresses lupus nephritis by reducing local iNOS expression and synthesis of anti-dsDNA antibody.
Takeda, Y., Takeno, M., Iwasaki, M., Kobayashi, H., Kirino, Y., Ueda, A., Nagahama, K., Aoki, I., and Ishigatsubo, Y
Clin Exp Immunol. 138:237-244, 2004
# A Point Mutation of Tyr-759 in Interleukin 6 Family Cytokine Receptor Subunit gp130 Causes Autoimmune Arthritis
T. Atsumi., K. Ishihara., D. Kamimura., H. Ikushima., T. Ohtani., S. Hirota., H. Kobayashi., S. Park., Y. Saeki., Y. Kitamura. and T. Hirano
J Exp Med, 196, Number 7, 979-990, 2002
# A novel assay kits for autoantibodies rate on spontaneous autoimmune model mice.
Kikukawa, T, Kojima, M., and Abe, C.
Jap J Inflammation 20: 697-701, 2000
# Increased expression of soluble form of vascular cell adhesion molecule-1 aggravates autoimmune arthritis in MRL-Fasipr mice.
Oishi, H., Mizuki, S., Terada, M., Kudo, M., Araki, K., Araki, M., Nose, M., and Takahashi, S.
Pathology International 57: 734-740, 2007
# Electro-acupuncture at acupoint ST36 reduces inflammation and regulates immune activity in collagen-induced arthritic mice.
Yim, Y.Y., Lee, H., Hong, K.E., Kim, Y.I., Lee, B.R., Son, C.G., and Kim, J.E.
Evidence-based Complementary and Alternative Medicine 4:51-57, 2007
# Requirement for CD100-CD72 interactions in fine-tuning of B-cell antigen receptor signaling and homeostatic maintenance of the B-cell compartment.
Kumanogoh, A., Shikina, T., Watanabe, C., Takegahara, N., Suzuki, K., Yamamoto, M., Takamatsu, H., Prasad, D.V.R., Mizui, M., Toyohuku, T., Tamaru, M., Watanabe, D., Parnes, J.R., and Kikutani, H.
International Immuno, 17: 1277-1282, 2005
# The point mutation of tyrosine 759 of the IL-6 family cytokine receptor gp130 synergizes with HTLV-1 pX in promoting rheumatoid arthritis-like arthritis.
Ishihara, K., Sawa, S., Ikushima, H., Hirota, S., Atsumi, T., Kamimura, D., Park, S.J., Murakami, M., Kitanuma, Y., Iwakura, Y., and Hirano, T.
International Immunol. 16: 455-465, 2004
# Chemical induction of HO-1 suppresses lupus nephritis by reducing local iNOS expression and synthesis of anti-dsDNA antibody.
Takeda, Y., Takeno, M., Iwasaki, M., Kobayashi, H., Kirino, Y., Ueda, A., Nagahama, K., Aoki, I., and Ishigatsubo, Y
Clin Exp Immunol. 138:237-244, 2004
# A Point Mutation of Tyr-759 in Interleukin 6 Family Cytokine Receptor Subunit gp130 Causes Autoimmune Arthritis
T. Atsumi., K. Ishihara., D. Kamimura., H. Ikushima., T. Ohtani., S. Hirota., H. Kobayashi., S. Park., Y. Saeki., Y. Kitamura. and T. Hirano
J Exp Med, 196, Number 7, 979-990, 2002
# A novel assay kits for autoantibodies rate on spontaneous autoimmune model mice.
Kikukawa, T, Kojima, M., and Abe, C.
Jap J Inflammation 20: 697-701, 2000
| Page top |
Mouse Rheumatoid Factor IgM Type ELISA Kit (AKRRG-111)
Original reports
#Lack of B and T lymphocyte attenuator exacerbates autoimmune disorders and induces Fas-independent liver injury in MRL-lpr/lpr mice
Y. Oya., N. Watanabe. Y. Kobayashi., T. Owada., M. Oki., K. Ikeda. A. Suto., S. Kagami., K. Hirose., T. Kishimoto., and H. Nakajima.
Int. Immunol. 23 (5): 335-344, 2011
#An experimental type 2 mixed cryoglobulinemia with renal glomerulopathy in ICR mice triggered by Capillaria hepatica infection
N. Aihara., J. K. Chambers., K. Hosono., J. Kamiie., and K. Shirota.
Histol Histopathol 26:1519-1529, 2011
# Point mutation of tyrosine 759 of the IL-6 family cytokine receptor,gp130,augments collagen-induced arthritis in DBA/IJ mice
Tsuji,F.,Yoshimi,M.,Katsuta,O.,Takai,M.,Ishihara,K.,Aono,H.
BMC Musculoskeletal Disorders ,10:23, 2009
# Implications for induction of autoimmunity via activation of B-1 cells by Helicobacter pylori urease.
Yamasnishi, S., Iizumi, T., Watanabe, E., Shimizu, M., Kamiya, S., Nagata, K., Kumagai, Y., Fukunaga, Y., and Takahashi, H.
Infection and Immunity, 74: 248-256 , 2006
# Cytokine production profile of splenocytes derived from zymosan A-treated SKG mice developing arthritis.
Kobayashi, K., Suda, T., Nan-ya, K., Sakaguchi, N., Sakaguchi, S., and Miki, I.
Inflammation Research 55:335-341, 2006
# Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages.
Kawane, K., Ohtani, M., Miwa, K., Kizawa, T., Kanbara, Y., Yoshioka, Y., and Yoshikawa,H.
Nature 443: 998-1002, 2006
# Requirement for CD100-CD72 interactions in fine-tuning of B-cell antigen receptor signaling and homeostatic maintenance of the B-cell compartment.
Kumanogoh, A., Shikina, T., Watanabe, C., Takegahara, N., Suzuki, K., Yamamoto, M., Takamatsu, H., Prasad, D.V.R., Mizui, M., Toyohuku, T., Tamaru, M., Watanabe, D., Parnes, J.R., and Kikutani, H.
International Immuno, 17: 1277-1282, 2005
# A Point Mutation of Tyr-759 in Interleukin 6 Family Cytokine Receptor Subunit gp130 Causes Autoimmune Arthritis
T. Atsumi., K. Ishihara., D. Kamimura., H. Ikushima., T. Ohtani., S. Hirota., H. Kobayashi., S. Park., Y. Saeki., Y. Kitamura. and T. Hirano
J Exp Med, 196, Number 7, 979-990, 2002
# A novel assay kits for autoantibodies rate on spontaneous autoimmune model mice.
Kikukawa, T, Kojima, M., and Abe, C.
Jap J Inflammation 20: 697-701, 2000
#Lack of B and T lymphocyte attenuator exacerbates autoimmune disorders and induces Fas-independent liver injury in MRL-lpr/lpr mice
Y. Oya., N. Watanabe. Y. Kobayashi., T. Owada., M. Oki., K. Ikeda. A. Suto., S. Kagami., K. Hirose., T. Kishimoto., and H. Nakajima.
Int. Immunol. 23 (5): 335-344, 2011
#An experimental type 2 mixed cryoglobulinemia with renal glomerulopathy in ICR mice triggered by Capillaria hepatica infection
N. Aihara., J. K. Chambers., K. Hosono., J. Kamiie., and K. Shirota.
Histol Histopathol 26:1519-1529, 2011
# Point mutation of tyrosine 759 of the IL-6 family cytokine receptor,gp130,augments collagen-induced arthritis in DBA/IJ mice
Tsuji,F.,Yoshimi,M.,Katsuta,O.,Takai,M.,Ishihara,K.,Aono,H.
BMC Musculoskeletal Disorders ,10:23, 2009
# Implications for induction of autoimmunity via activation of B-1 cells by Helicobacter pylori urease.
Yamasnishi, S., Iizumi, T., Watanabe, E., Shimizu, M., Kamiya, S., Nagata, K., Kumagai, Y., Fukunaga, Y., and Takahashi, H.
Infection and Immunity, 74: 248-256 , 2006
# Cytokine production profile of splenocytes derived from zymosan A-treated SKG mice developing arthritis.
Kobayashi, K., Suda, T., Nan-ya, K., Sakaguchi, N., Sakaguchi, S., and Miki, I.
Inflammation Research 55:335-341, 2006
# Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages.
Kawane, K., Ohtani, M., Miwa, K., Kizawa, T., Kanbara, Y., Yoshioka, Y., and Yoshikawa,H.
Nature 443: 998-1002, 2006
# Requirement for CD100-CD72 interactions in fine-tuning of B-cell antigen receptor signaling and homeostatic maintenance of the B-cell compartment.
Kumanogoh, A., Shikina, T., Watanabe, C., Takegahara, N., Suzuki, K., Yamamoto, M., Takamatsu, H., Prasad, D.V.R., Mizui, M., Toyohuku, T., Tamaru, M., Watanabe, D., Parnes, J.R., and Kikutani, H.
International Immuno, 17: 1277-1282, 2005
# A Point Mutation of Tyr-759 in Interleukin 6 Family Cytokine Receptor Subunit gp130 Causes Autoimmune Arthritis
T. Atsumi., K. Ishihara., D. Kamimura., H. Ikushima., T. Ohtani., S. Hirota., H. Kobayashi., S. Park., Y. Saeki., Y. Kitamura. and T. Hirano
J Exp Med, 196, Number 7, 979-990, 2002
# A novel assay kits for autoantibodies rate on spontaneous autoimmune model mice.
Kikukawa, T, Kojima, M., and Abe, C.
Jap J Inflammation 20: 697-701, 2000
| Page top |
OVA IgE ELISA KIT (AKRIE-030)
Original reports
#Urban particulate matter in Beijin,China,enhances allergen-induced murine lung eosinophilia
He,M.,Ichinose,T.,Yoshida,S.,Nishikawa,M.,Mori,I.,Yanagisawa,R.,Takano,H.,Inoue,K.,Sun,G.,Shibamoto,T.
Inhalation Toxicology 22(9):709-718,August,2010
#Peritoneal injection of fucoidan suppresses the increase of plasma IgE induced by OVA-sensitization
Yanase,Y.,Hiragun,T.,Uchida,K.,Ishii,K.,Oomizu,S.,Suzuki,H.,Mihara,S.,Iwamoto,K.,
Matsuo,H.,Onishi,N.,Kameyoshi,Y.,and Hide,M.
Biochemical and Biophysical Research Communications 387:3:435- 439,2009
#Peroxisome Proliferator-Activated Receptor gNegatively Regulates Allergic Rhinitis in Mice
Fukui,N.,Honda,K.,Ito,E.,and Ishikawa K.
Allergology Internatioal.58:247-253,2009
#IL-16 Variabillity and Modulation by Antiallergic Drugs in a Murine Experimental Allergic Rhinitis Model
Akiyama,K.,Karaki,M.,Kobayshi,R.,Dobashi,H.,Ishida,T, and Mori,N.
Allergy and Immunology 149:4,2009
#Frequency of Foxp3+CD4+CD25+ T cell is associated with the phenotypes of allergic asthma
Matsumoto,K.,Inoue,H.,Fukuyama,A.,Kan,O,K.,Eguchi,T,M.,Matsumoto,T.,Moriwaki,A.,
Nakano,T., and Nakanishi,Y.
Respirology 14:2,2009
# Differential Regulatory Function of Resting and Preactivated Allergen-Specific CD4+CD25+
Regulatory T Cells in Th2-Type Airway Inflammation
Saito, K., Torii, M., Ning Ma, Tsuchiya, T., Wang, L., Hori, T., Nagakubo, D., Nitta, N.,
Kanegasaki, S., Hieshima, K., Yoshie, O., Gabazza, E.C., Katayama, N., Shiku, H.,
Kuribayashi, K. and Kato, T.
The Journal of Immunology, 181:6889-6897, 2008
# Effects of Asian Sand Dust, Arizona Sand Dust, Amorphous Silica and Aluminum Oxide on
Allergic Inflammation in the Murine Lung
Ichinose, T., Yoshida, S., Sadakane, K., Takano, H., Yanagizawa, R., Inoue, K., Nishikawa, M.,
Mori, I., Kawazato, H., Yasuda, A. and Shibamoto, T.
Inhalation Toxicology, Volume 20, Issue 7, 685-694, 2008
#Effects of Asian Sand Dust,Arizona Sand Dust,Amorphous Sillica and Aluminum Oxide on Allergic Inflammation in the Murine Lung
Ichinose,T.,Yoshida,S.,Sadakane,K.,Takano,H.,Yanagisawa,R.,Inoue,K.,Nishikawa,M.,Mori,I.,
Yasuda,A.,and Shibamoto,T.
Inhalation toxicology 20:7:685-694,2008
#The Effects of Microbial Materials Adhered to Asian Sand Dust on Allergic Lung Inflammation
Ichinose,T.,Yoshida,S.,Hiyoshi,K.,Sadakane,K.,Takano,H.,Nishikawa,M.,Mori,I.,
Yanagisawa,R.,Kawazato,H.,Yasuda,A., and Shibamoto,T.
Arch Environ Contam Toxicol 55:348-357,2008
#Differential Regulatory Function of Resting and Preactivated Allergen-Specific CD4+CD25+ Regulatory T cell in Th2-Type Airway Inflammation
Saito,K.,Torii,M.,Ma,N.,Tsuchiya,T.,Wang,L.,Hori,T.,Nagakubo,D.,Nitta,N.,Kanegasaki,S.,
Hieshima,K.,Yoshie,O.,Gabazza,E,C.,Katayama,N.,Shiku,H.,Kuribayashi,K., and Kato,T.
The Journal of Immunology 181:6889-6897,2008
#Urban particulate matter in Beijin,China,enhances allergen-induced murine lung eosinophilia
He,M.,Ichinose,T.,Yoshida,S.,Nishikawa,M.,Mori,I.,Yanagisawa,R.,Takano,H.,Inoue,K.,Sun,G.,Shibamoto,T.
Inhalation Toxicology 22(9):709-718,August,2010
#Peritoneal injection of fucoidan suppresses the increase of plasma IgE induced by OVA-sensitization
Yanase,Y.,Hiragun,T.,Uchida,K.,Ishii,K.,Oomizu,S.,Suzuki,H.,Mihara,S.,Iwamoto,K.,
Matsuo,H.,Onishi,N.,Kameyoshi,Y.,and Hide,M.
Biochemical and Biophysical Research Communications 387:3:435- 439,2009
#Peroxisome Proliferator-Activated Receptor gNegatively Regulates Allergic Rhinitis in Mice
Fukui,N.,Honda,K.,Ito,E.,and Ishikawa K.
Allergology Internatioal.58:247-253,2009
#IL-16 Variabillity and Modulation by Antiallergic Drugs in a Murine Experimental Allergic Rhinitis Model
Akiyama,K.,Karaki,M.,Kobayshi,R.,Dobashi,H.,Ishida,T, and Mori,N.
Allergy and Immunology 149:4,2009
#Frequency of Foxp3+CD4+CD25+ T cell is associated with the phenotypes of allergic asthma
Matsumoto,K.,Inoue,H.,Fukuyama,A.,Kan,O,K.,Eguchi,T,M.,Matsumoto,T.,Moriwaki,A.,
Nakano,T., and Nakanishi,Y.
Respirology 14:2,2009
# Differential Regulatory Function of Resting and Preactivated Allergen-Specific CD4+CD25+
Regulatory T Cells in Th2-Type Airway Inflammation
Saito, K., Torii, M., Ning Ma, Tsuchiya, T., Wang, L., Hori, T., Nagakubo, D., Nitta, N.,
Kanegasaki, S., Hieshima, K., Yoshie, O., Gabazza, E.C., Katayama, N., Shiku, H.,
Kuribayashi, K. and Kato, T.
The Journal of Immunology, 181:6889-6897, 2008
# Effects of Asian Sand Dust, Arizona Sand Dust, Amorphous Silica and Aluminum Oxide on
Allergic Inflammation in the Murine Lung
Ichinose, T., Yoshida, S., Sadakane, K., Takano, H., Yanagizawa, R., Inoue, K., Nishikawa, M.,
Mori, I., Kawazato, H., Yasuda, A. and Shibamoto, T.
Inhalation Toxicology, Volume 20, Issue 7, 685-694, 2008
#Effects of Asian Sand Dust,Arizona Sand Dust,Amorphous Sillica and Aluminum Oxide on Allergic Inflammation in the Murine Lung
Ichinose,T.,Yoshida,S.,Sadakane,K.,Takano,H.,Yanagisawa,R.,Inoue,K.,Nishikawa,M.,Mori,I.,
Yasuda,A.,and Shibamoto,T.
Inhalation toxicology 20:7:685-694,2008
#The Effects of Microbial Materials Adhered to Asian Sand Dust on Allergic Lung Inflammation
Ichinose,T.,Yoshida,S.,Hiyoshi,K.,Sadakane,K.,Takano,H.,Nishikawa,M.,Mori,I.,
Yanagisawa,R.,Kawazato,H.,Yasuda,A., and Shibamoto,T.
Arch Environ Contam Toxicol 55:348-357,2008
#Differential Regulatory Function of Resting and Preactivated Allergen-Specific CD4+CD25+ Regulatory T cell in Th2-Type Airway Inflammation
Saito,K.,Torii,M.,Ma,N.,Tsuchiya,T.,Wang,L.,Hori,T.,Nagakubo,D.,Nitta,N.,Kanegasaki,S.,
Hieshima,K.,Yoshie,O.,Gabazza,E,C.,Katayama,N.,Shiku,H.,Kuribayashi,K., and Kato,T.
The Journal of Immunology 181:6889-6897,2008
| Page top |
Rabbit CRP ELISA kit (AKRCR-017)
Original reports
# C-reactive protein in atherosclerotic lesions: its origin and pathophysiological significance
Sun, H., Koike, T., Ichikawa, T., Hatakeyama, K., Shiomi, M., Zhang, B., Kitajima, S.,
Morimoto, M., Watanabe, T., Asada, Y., Chen, Y. E., and Fan, J.
Am. J. Pathol. 167:1139-1148, 2005
# C-reactive protein in atherosclerotic lesions: its origin and pathophysiological significance
Sun, H., Koike, T., Ichikawa, T., Hatakeyama, K., Shiomi, M., Zhang, B., Kitajima, S.,
Morimoto, M., Watanabe, T., Asada, Y., Chen, Y. E., and Fan, J.
Am. J. Pathol. 167:1139-1148, 2005
| Page top |
Mouse IgE ELISA kit (AKRIE-010)
Original reports
# Improvement of the Antiinflammatory and Antiallergic Activity of Bidens pilosa L. var. radiata
SCHERFF Treated with Enzyme (Cellulosine)
Horiuchi, M. and Seyama, Y.
Journal of Health Science, Vol. 54(2008), No.3 294-301
# Suppression of spontaneous dermatitis in NC/Nga murine model by PG102 isolated from Actinidia arguta
Park, E.J., Park, K.C., Eo, H, Seo, J., Son, M., Kim, K.H. et al.
J Investigative Dermatology, 127: 1154-1160, 2007
# Sopungyangjae-Tang inhibits development of dermatitis in Nc/Nga mice
Pokharel, Y.R., Lim, S.C., Kim, S.C., Heo, T.H., Choi, H.K. and Kang, K.W.
Evidence-based Complementary and Alternative Medicine nem015, 1-8, March 12, 2007
# Inhibitory effect of DA-9201, an extract of Oryza sativa L., on airway inflammation and bronchial hyperresponsiveness in mouse asthma model.
Lee, S.H., Sohm, Y.S., Kang, K.K., Kwon, J.W. and Yoo, M.
Biol. Pharm. Bull. 29(6), 1148-1153, 2006
# A new symbiotic, Lactobacillus casei subsp. casei together with dextran, reduces murine and human allergic reaction.
Ogawa, T., Hashikawa, S., Asai, Y., Sakamoto, H., Yasuda, K., and Makimura, Y.
FEMS Immunology and Medical Microbiology, 46:400-409, 2006
# Effects of alpha tocopherol and probucol supplements on allergen-induced airway inflammation and hyperresponsiveness in a mouse model of allergic asthma.
Okamoto, N., Murata, T., Tamai, H., Tanaka, H., and Nagai, H.
Int. Allergy Immunol. 141: 172-180, 2006
# Control of IgE and selective TH1 and TH2 cytokines by PG102 isolated from Actinidia arguta.
Parkm E.J., Kim, B., Eo, H., Park, K, Kim, Y., Lee, H.J. and Son, M.
J Allergy and Clinical Immunol,1151-1167,2005
# Oral immunotherapy against a pollen allergy using a seed-based peptide vaccine.
Takagi, H., Saito, S., Yang, L., Nagasawa, S., Nishizawa, N., and Takaiwa, F.
Plant Biotechnology Journal 3: 521-533, 2005
# Activated protein C inhibits bronchial hyperresponsiveness and Th2 cytokine expression in mice
Hisamichi Yuda, Yukihiko Adachi, Osamu Taguchi, Esteban C. Gabazza, Osamu Hataji, Hajime Fujimoto, Shigenori Tamaki, Kimiaki Nishikubo, Kenji Fukudome, Corina N. D'Alessandro-Gabazza, Junko Maruyama, Masahiko Izumizaki, Michiko Iwase, Ikuo Homma, Ryo Inoue, Haruhiko Kamada, Tatsuya Hayashi, Michael Kasper, Bart N. Lambrecht, Peter J. Barnes, and Koji Suzuki
Blood, 103, No. 6, 2196-2204, 2004
# Inadequate induction of suppressor of cytokine signaling-1 causes systemic autoimmune diseases.
Fujimoto, M., Tsutsui, H., Xinshou, O., Tokumoto, M., Watanabe, D., Shima, Y., Yoshimoto, T., Hirakata, H., Kawase, I., Nakanishi, K., Kishimoto, T., and Naka, T.
International Immunology 16:303-314, 2004
# Association of cathepsin E deficiency with development of atopic dermatitis
Tsukuba, T., Okamoto, K., Okamoto, Y., Yanagawa, M.
J Biochemistry, 134:893-902, 2003
# Mast-cell-dependent histamine release after praziquantel treatment of Schistosoma japonicum infection: implications for chemotherapy-related adverse effects
Jun Matsumoto and Hajime Matsuda
Parasitology Research . 88, 888 - 893, 2002
# Improvement of the Antiinflammatory and Antiallergic Activity of Bidens pilosa L. var. radiata
SCHERFF Treated with Enzyme (Cellulosine)
Horiuchi, M. and Seyama, Y.
Journal of Health Science, Vol. 54(2008), No.3 294-301
# Suppression of spontaneous dermatitis in NC/Nga murine model by PG102 isolated from Actinidia arguta
Park, E.J., Park, K.C., Eo, H, Seo, J., Son, M., Kim, K.H. et al.
J Investigative Dermatology, 127: 1154-1160, 2007
# Sopungyangjae-Tang inhibits development of dermatitis in Nc/Nga mice
Pokharel, Y.R., Lim, S.C., Kim, S.C., Heo, T.H., Choi, H.K. and Kang, K.W.
Evidence-based Complementary and Alternative Medicine nem015, 1-8, March 12, 2007
# Inhibitory effect of DA-9201, an extract of Oryza sativa L., on airway inflammation and bronchial hyperresponsiveness in mouse asthma model.
Lee, S.H., Sohm, Y.S., Kang, K.K., Kwon, J.W. and Yoo, M.
Biol. Pharm. Bull. 29(6), 1148-1153, 2006
# A new symbiotic, Lactobacillus casei subsp. casei together with dextran, reduces murine and human allergic reaction.
Ogawa, T., Hashikawa, S., Asai, Y., Sakamoto, H., Yasuda, K., and Makimura, Y.
FEMS Immunology and Medical Microbiology, 46:400-409, 2006
# Effects of alpha tocopherol and probucol supplements on allergen-induced airway inflammation and hyperresponsiveness in a mouse model of allergic asthma.
Okamoto, N., Murata, T., Tamai, H., Tanaka, H., and Nagai, H.
Int. Allergy Immunol. 141: 172-180, 2006
# Control of IgE and selective TH1 and TH2 cytokines by PG102 isolated from Actinidia arguta.
Parkm E.J., Kim, B., Eo, H., Park, K, Kim, Y., Lee, H.J. and Son, M.
J Allergy and Clinical Immunol,1151-1167,2005
# Oral immunotherapy against a pollen allergy using a seed-based peptide vaccine.
Takagi, H., Saito, S., Yang, L., Nagasawa, S., Nishizawa, N., and Takaiwa, F.
Plant Biotechnology Journal 3: 521-533, 2005
# Activated protein C inhibits bronchial hyperresponsiveness and Th2 cytokine expression in mice
Hisamichi Yuda, Yukihiko Adachi, Osamu Taguchi, Esteban C. Gabazza, Osamu Hataji, Hajime Fujimoto, Shigenori Tamaki, Kimiaki Nishikubo, Kenji Fukudome, Corina N. D'Alessandro-Gabazza, Junko Maruyama, Masahiko Izumizaki, Michiko Iwase, Ikuo Homma, Ryo Inoue, Haruhiko Kamada, Tatsuya Hayashi, Michael Kasper, Bart N. Lambrecht, Peter J. Barnes, and Koji Suzuki
Blood, 103, No. 6, 2196-2204, 2004
# Inadequate induction of suppressor of cytokine signaling-1 causes systemic autoimmune diseases.
Fujimoto, M., Tsutsui, H., Xinshou, O., Tokumoto, M., Watanabe, D., Shima, Y., Yoshimoto, T., Hirakata, H., Kawase, I., Nakanishi, K., Kishimoto, T., and Naka, T.
International Immunology 16:303-314, 2004
# Association of cathepsin E deficiency with development of atopic dermatitis
Tsukuba, T., Okamoto, K., Okamoto, Y., Yanagawa, M.
J Biochemistry, 134:893-902, 2003
# Mast-cell-dependent histamine release after praziquantel treatment of Schistosoma japonicum infection: implications for chemotherapy-related adverse effects
Jun Matsumoto and Hajime Matsuda
Parasitology Research . 88, 888 - 893, 2002
| Page top |
Rat IgE ELISA kit (AKRIE-011)
Original reports
#Enhancement of the pulmonary allergic granulocyte recruitment in rats exposed to DMTI-II,a Kunitz-type inhibitor isolated from Dimorphandra mollis seeds
Glaucia,C,M.,Karina,F,R.,Dalize,M,S.,Andre,A,S.,Ivani,A,de S.,Maria,L R,M.,Edson,A.
International Immunopharmacology, Volume 11, Issues 6, June 2011, 740-747
# Altered cytokine expression in mesenteric lymph nodes in a rat strain (Matsumoto Eosinophilic Shinshyu) that spontaneously develops hypereosinophilia.
Muto, S., Monnai, M., Okuhara, Y., Murakami, M., Kuroda, J., Ono, T., and Matsumoto, K.
Immunology 116: 373-380, 2005
#Enhancement of the pulmonary allergic granulocyte recruitment in rats exposed to DMTI-II,a Kunitz-type inhibitor isolated from Dimorphandra mollis seeds
Glaucia,C,M.,Karina,F,R.,Dalize,M,S.,Andre,A,S.,Ivani,A,de S.,Maria,L R,M.,Edson,A.
International Immunopharmacology, Volume 11, Issues 6, June 2011, 740-747
# Altered cytokine expression in mesenteric lymph nodes in a rat strain (Matsumoto Eosinophilic Shinshyu) that spontaneously develops hypereosinophilia.
Muto, S., Monnai, M., Okuhara, Y., Murakami, M., Kuroda, J., Ono, T., and Matsumoto, K.
Immunology 116: 373-380, 2005
| Page top |
Rat albumin TIA kit (AKRAL-020)
Original reports
# Mizoribine reduces renal injury and macrophage infiltration in non-insulin-dependent diabetic rats.
Kikuchi, Y., Imakiire, T., Yamada, Y., Saigusa, T, Hyodo, T, Hyodo, N., Suzuki, S., and Miura, S.
Nephrology Dialysis Transplantation 20: 1573-1581, 2005
# Renoprotective effects of tea catechin in streptozotocin-induced diabetic rats.
Hase, H., Babazono, T., Karibe, S., Kinae, N., and Iwamoto, Y.
International Urology and Nephrology 38: 693-699
# Mizoribine reduces renal injury and macrophage infiltration in non-insulin-dependent diabetic rats.
Kikuchi, Y., Imakiire, T., Yamada, Y., Saigusa, T, Hyodo, T, Hyodo, N., Suzuki, S., and Miura, S.
Nephrology Dialysis Transplantation 20: 1573-1581, 2005
# Renoprotective effects of tea catechin in streptozotocin-induced diabetic rats.
Hase, H., Babazono, T., Karibe, S., Kinae, N., and Iwamoto, Y.
International Urology and Nephrology 38: 693-699
| Page top |
Mouse albumin ELISA kit (AKRAL-120)
Original reports
#CCR2 antagonism improves insulin resistance, lipid metabolism, and diabetic nephropathy in type 2 diabetic mice
Kang,Y.S.,Lee,M.H.,Song,H.K.,Ko,G.J.,Kwon,O.S.,Lim,T.K.,Kim,S.H.,Han,S.Y.,Hyun,K.
Kidney International 78:883-894,November(1),2010
# Rubratoxin B induces interleukin-6 secretion in mouse white
Adipose tissues and 3T3-L1 adipocytes.
Keiko Iwashita,Hitoshi Nagashima
Toxicology Letters 182,79-83,2008
# Deterioration of atherosclerosis in mice lacking angiotensin II type 1A receptor in bone marrow-derived cells.
Kato,H., Ishida,J., Nagano,K., Honjo,K., Sugaya,T., Takeda,N., Sugiyama,F., Yagami,K., Fujita,T., Nangaku,M., and Fukamizu, A.
Lab Invest., 88(7):731-9, 2008
# Differentiation of mouse and human embryonic stem cells into hepatic lineages.
Shiraki,N., Umeda,K., Sakashita,N., Takeya,M., Kume,K., and Kume, S.
Genes to Cells, 13, pp.731-746, 2008
# Effect of Lactobacillus jonsonii La1 on immune function and serum albumin in aged and malnourished aged mice.
Kaburagi, T., Yamano, T., Fukushima, Y, Yoshino, H., Mito, N., and Sato, K.
Nutrition 24: 342-350, 2007
# Differentiation of mouse embryonic stem cells to hepatocyto-like cells by co-culture with human liver nonparenchymal cell lines.
Soto-Gutierrez, A., Navarro-Alvarez, N., Zhao, D., Rivas, J.D., Rivas-Carillo, J.D., Lebkowski, J., Tanaka, N., Fox, I.J., and Kobayashi, N.
Nature Protocols. Electronic Edition 2: 347-356, 2007
# Construction and transplantation of an engineered hepatic tissue using a polyaminourethane-coated nonwoven polytetrafluoroethylene fabric.
Soto-Gutierrez, A., Navarro-Alvarez, N., Rivas, J.D., Tanaka, K., Chen, Y., Misawa, H., Okitsu, T., Noguchi, H., Tanaka, N., and Kobayashi, N.
Transplantation 83: 129-137, 2007
# Pitavastatin ameliorates albuminuria and renal mesangial expansion by downregulating NOX4 in db/db mice.
Fujii, M., Inoguchi, T., Maeda, Y., Sasaki, S., Sawada, F., saito, R., Kobayashi, K., Sumitomo, H., and Takayanagi, R.
Kidney International 72: 473-480, 2007
# Murine embryonic stem cell-derived hepatic tissue system.
Tsutsui, M., Ogawa, S., Inada, Y., Tomioka, E., Kamiyoshi, A., Tanaka, S., Kishida, S., Nishiyama, M., Murakami, M., Kuroda, J., Hashikura, Y., Miyagawa, S., satoh, F., shibata, N., and Tagawa, Y.
Drug Metabolism and Disposition 34: 696-701, 2006
# Growth factor midkine is involved in the pathogenesis of diabetic nephropathy.
Kosugi, T., Yuzawa, Y., sato, W., Kawai, H., Matsuo, S.,Takei,Y.,Muramatsu,T., and Kadomatsu,K.
Am J Pathology 168: 9-19, 2006
# Characterization of cytochrome P450 expression in murine embryonic stem cell-derived hepatic tissue system
Tsutsui,M., Ogawa,S., Inada,Y., Tomioka,E., Kammiyoshi,A., Tanaka,S., Kishida,T., Nishiyama,M., Murakami,M., Kuroda,J., Hashikura,Y., Miyagawa,S., Satoh,F., Shibata,N., and Tagawa,Y.
The American Society for Pharmacology and Experimental Thera- peutics,34:696-701,2006
# Supplementation with chromium picolinate recovers renal Cr concentration and improves carbohydrate metabolism and renal function in type 2 diabetic mice.
Mita, Y., Ishihara, K., Fukuchi, Y., Fukuya, Y., and Yasumoto, K.
Biological Trace Element Research 105: 229-248, 2005
# Tissue array substratum composed of histological sections: A new platform for orienting differentiation of embryonic stem cells towards hepatic lineage.
Takeuchi, T., Ochiya, T., and Takezawa, T.
Tissue Engineering ahead of print 14(2)
#CCR2 antagonism improves insulin resistance, lipid metabolism, and diabetic nephropathy in type 2 diabetic mice
Kang,Y.S.,Lee,M.H.,Song,H.K.,Ko,G.J.,Kwon,O.S.,Lim,T.K.,Kim,S.H.,Han,S.Y.,Hyun,K.
Kidney International 78:883-894,November(1),2010
# Rubratoxin B induces interleukin-6 secretion in mouse white
Adipose tissues and 3T3-L1 adipocytes.
Keiko Iwashita,Hitoshi Nagashima
Toxicology Letters 182,79-83,2008
# Deterioration of atherosclerosis in mice lacking angiotensin II type 1A receptor in bone marrow-derived cells.
Kato,H., Ishida,J., Nagano,K., Honjo,K., Sugaya,T., Takeda,N., Sugiyama,F., Yagami,K., Fujita,T., Nangaku,M., and Fukamizu, A.
Lab Invest., 88(7):731-9, 2008
# Differentiation of mouse and human embryonic stem cells into hepatic lineages.
Shiraki,N., Umeda,K., Sakashita,N., Takeya,M., Kume,K., and Kume, S.
Genes to Cells, 13, pp.731-746, 2008
# Effect of Lactobacillus jonsonii La1 on immune function and serum albumin in aged and malnourished aged mice.
Kaburagi, T., Yamano, T., Fukushima, Y, Yoshino, H., Mito, N., and Sato, K.
Nutrition 24: 342-350, 2007
# Differentiation of mouse embryonic stem cells to hepatocyto-like cells by co-culture with human liver nonparenchymal cell lines.
Soto-Gutierrez, A., Navarro-Alvarez, N., Zhao, D., Rivas, J.D., Rivas-Carillo, J.D., Lebkowski, J., Tanaka, N., Fox, I.J., and Kobayashi, N.
Nature Protocols. Electronic Edition 2: 347-356, 2007
# Construction and transplantation of an engineered hepatic tissue using a polyaminourethane-coated nonwoven polytetrafluoroethylene fabric.
Soto-Gutierrez, A., Navarro-Alvarez, N., Rivas, J.D., Tanaka, K., Chen, Y., Misawa, H., Okitsu, T., Noguchi, H., Tanaka, N., and Kobayashi, N.
Transplantation 83: 129-137, 2007
# Pitavastatin ameliorates albuminuria and renal mesangial expansion by downregulating NOX4 in db/db mice.
Fujii, M., Inoguchi, T., Maeda, Y., Sasaki, S., Sawada, F., saito, R., Kobayashi, K., Sumitomo, H., and Takayanagi, R.
Kidney International 72: 473-480, 2007
# Murine embryonic stem cell-derived hepatic tissue system.
Tsutsui, M., Ogawa, S., Inada, Y., Tomioka, E., Kamiyoshi, A., Tanaka, S., Kishida, S., Nishiyama, M., Murakami, M., Kuroda, J., Hashikura, Y., Miyagawa, S., satoh, F., shibata, N., and Tagawa, Y.
Drug Metabolism and Disposition 34: 696-701, 2006
# Growth factor midkine is involved in the pathogenesis of diabetic nephropathy.
Kosugi, T., Yuzawa, Y., sato, W., Kawai, H., Matsuo, S.,Takei,Y.,Muramatsu,T., and Kadomatsu,K.
Am J Pathology 168: 9-19, 2006
# Characterization of cytochrome P450 expression in murine embryonic stem cell-derived hepatic tissue system
Tsutsui,M., Ogawa,S., Inada,Y., Tomioka,E., Kammiyoshi,A., Tanaka,S., Kishida,T., Nishiyama,M., Murakami,M., Kuroda,J., Hashikura,Y., Miyagawa,S., Satoh,F., Shibata,N., and Tagawa,Y.
The American Society for Pharmacology and Experimental Thera- peutics,34:696-701,2006
# Supplementation with chromium picolinate recovers renal Cr concentration and improves carbohydrate metabolism and renal function in type 2 diabetic mice.
Mita, Y., Ishihara, K., Fukuchi, Y., Fukuya, Y., and Yasumoto, K.
Biological Trace Element Research 105: 229-248, 2005
# Tissue array substratum composed of histological sections: A new platform for orienting differentiation of embryonic stem cells towards hepatic lineage.
Takeuchi, T., Ochiya, T., and Takezawa, T.
Tissue Engineering ahead of print 14(2)
| Page top |
Rat albumin ELISA kit (AKRAL-121)
Original reports
# Cold Preservation of the Liver With Oxygenation by a Two-Layer Method.
Odaira,M., Aoki,T., Miyamoto,Y., Yasuhara,R., Jin,Z., Yu,J., Nishino,N., Yamada,K., Kusano,T., Hayashi,K., Yasuda,D., Koizumi,T., Mitamura,K., Enami,Y., Niiya,T., Murai,N., Kato,H., Shimizu,Y., Kamijyo,R., and Kusano, M.
Journal of Surgical Research, Volume 152, Issue 2, pp. 209-217, 2009
# Cell processing on polyimide surface patterned by rubbing.
Matsumoto,N.,Hiruma,H.,Nagaoka,S.,Fujiyama,K.,Kaneko,A., and Kawakami, H.
Polymers for Advanced Technologies, Volume 19, Issue 8, pp.1002-1008, 2008
# Antidiabetic effect of long-term supplementation with Siraitia grosvenori on the spontaneously diabetic Goto-Kakizaki rat.
Suzuki, Y.A., Tomoda, M., Murata Y., Inui, H., Sugiura, M., and Nakano, Y.
British J Nutrition 97: 770-775, 2007
# Hepatocyte transplantation from steatotic liver in a rat model.
Hayashi, K., Aoki, T., Jin, Z., Wang, H., Nishino, N., Kusano, T., Yasuda, D., Koizumi, T., Enami, Y., and Odaira, M.
J Surgical Research 142: 104-112, 2007
# Dietary nitrite inhibits early glomerular injury in streptozotocin-induced diabetic nephropathy in rats.
Ohtake, K., Ishiyama, Y., Uchida, H., Muraki, E., and Kobayashi, J.
Nitric Oxide 17: 75-81, 2007
# Spironolactone ameriolates renal injuary and connective tissue growth factor expression in type II diabetic rats.
Han, K.H., Kang, Y.S., Han, S.Y., Jee, Y.H., Lee, M.H., Han, J.Y., Kim, H.K., Kim, Y.S., and Cha, D.R.
Kidney International 70:111-120, 2006
# High functional hollow fiber membrane modified with phospholipid polymers for a liver assist bioreactor.
Ye, S.H., Watanabe, J., Takai, M., Iwasaki, Y., and Ishihara, K.
Biomaterials 27: 1955-1962, 2006
# Spironolactone prevents diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats.
Han,S.Y., Kim, C.H., Kim, H.S., Jee, Y.H., Song, H.K., Lee, M.H., Han, K.H., Kim, H.K., Kang, Y.S., Han, J.Y., Kim, Y.S. and Cha, D.R.
J Am Soc Nephrology 17: 1362-1372, 2006
# Efficient in vivo xenogeneic retroviral vector-mediated gene transduction into human Hepatocytes.
Kentaro Emoto, Chise Tateno, Hiroshi Hino, Hironobu Amano, Yasuhiro Imaoka, Kinji Asahina, Toshimasa, Asahara, and Katsutoshi Yoshizato
Human Gene Therapy, 16: 1168-1174, 2005
# In vivo engineering of metabolically active hepatic tissue in a neovascularized subcutaneous cavity.
Yokoyama, T., Ohashi, K., Kuge, H., Kanehiro, H., Iwata, H., Yamato, M., and Nakajima, Y.
Am J Transplantation 6: 50-59, 2005
# Effect of retinoic acid in experimental diabetic nephropathy.
Han, S.Y., so, G.A., Jee, Y.H., Han, K.H., Kang, Y.S., Kim, H.K., Kang, S.W., Han, D.S., Han, J.Y., and Cha, D.R.
Immunol Cell Biol 82: 568-576, 2004
# Enhanced activity of serum and urinary hyaluronidases in streptozotocin-induced diabetic Wister and GK rats.
Ikegami-Kawai, M., Okuda, R., Nemoto, T., Inada, N., and Takahashi, T.
Glycobiology 14: 65-72, 2004
# Cold Preservation of the Liver With Oxygenation by a Two-Layer Method.
Odaira,M., Aoki,T., Miyamoto,Y., Yasuhara,R., Jin,Z., Yu,J., Nishino,N., Yamada,K., Kusano,T., Hayashi,K., Yasuda,D., Koizumi,T., Mitamura,K., Enami,Y., Niiya,T., Murai,N., Kato,H., Shimizu,Y., Kamijyo,R., and Kusano, M.
Journal of Surgical Research, Volume 152, Issue 2, pp. 209-217, 2009
# Cell processing on polyimide surface patterned by rubbing.
Matsumoto,N.,Hiruma,H.,Nagaoka,S.,Fujiyama,K.,Kaneko,A., and Kawakami, H.
Polymers for Advanced Technologies, Volume 19, Issue 8, pp.1002-1008, 2008
# Antidiabetic effect of long-term supplementation with Siraitia grosvenori on the spontaneously diabetic Goto-Kakizaki rat.
Suzuki, Y.A., Tomoda, M., Murata Y., Inui, H., Sugiura, M., and Nakano, Y.
British J Nutrition 97: 770-775, 2007
# Hepatocyte transplantation from steatotic liver in a rat model.
Hayashi, K., Aoki, T., Jin, Z., Wang, H., Nishino, N., Kusano, T., Yasuda, D., Koizumi, T., Enami, Y., and Odaira, M.
J Surgical Research 142: 104-112, 2007
# Dietary nitrite inhibits early glomerular injury in streptozotocin-induced diabetic nephropathy in rats.
Ohtake, K., Ishiyama, Y., Uchida, H., Muraki, E., and Kobayashi, J.
Nitric Oxide 17: 75-81, 2007
# Spironolactone ameriolates renal injuary and connective tissue growth factor expression in type II diabetic rats.
Han, K.H., Kang, Y.S., Han, S.Y., Jee, Y.H., Lee, M.H., Han, J.Y., Kim, H.K., Kim, Y.S., and Cha, D.R.
Kidney International 70:111-120, 2006
# High functional hollow fiber membrane modified with phospholipid polymers for a liver assist bioreactor.
Ye, S.H., Watanabe, J., Takai, M., Iwasaki, Y., and Ishihara, K.
Biomaterials 27: 1955-1962, 2006
# Spironolactone prevents diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats.
Han,S.Y., Kim, C.H., Kim, H.S., Jee, Y.H., Song, H.K., Lee, M.H., Han, K.H., Kim, H.K., Kang, Y.S., Han, J.Y., Kim, Y.S. and Cha, D.R.
J Am Soc Nephrology 17: 1362-1372, 2006
# Efficient in vivo xenogeneic retroviral vector-mediated gene transduction into human Hepatocytes.
Kentaro Emoto, Chise Tateno, Hiroshi Hino, Hironobu Amano, Yasuhiro Imaoka, Kinji Asahina, Toshimasa, Asahara, and Katsutoshi Yoshizato
Human Gene Therapy, 16: 1168-1174, 2005
# In vivo engineering of metabolically active hepatic tissue in a neovascularized subcutaneous cavity.
Yokoyama, T., Ohashi, K., Kuge, H., Kanehiro, H., Iwata, H., Yamato, M., and Nakajima, Y.
Am J Transplantation 6: 50-59, 2005
# Effect of retinoic acid in experimental diabetic nephropathy.
Han, S.Y., so, G.A., Jee, Y.H., Han, K.H., Kang, Y.S., Kim, H.K., Kang, S.W., Han, D.S., Han, J.Y., and Cha, D.R.
Immunol Cell Biol 82: 568-576, 2004
# Enhanced activity of serum and urinary hyaluronidases in streptozotocin-induced diabetic Wister and GK rats.
Ikegami-Kawai, M., Okuda, R., Nemoto, T., Inada, N., and Takahashi, T.
Glycobiology 14: 65-72, 2004
| Page top |
Bovine Albumin ELISA KIT (AKRBS-018)
Original reports
# Rapid production of protein-loaded biodegradable microparticles using surface acoustic waves.
Alvarex,M.,Yeo,L.Y.,Friend,J.R., and Jamriska, M.
Biomicrofluidics 3, 014102, 2009
# Rapid production of protein-loaded biodegradable microparticles using surface acoustic waves.
Alvarex,M.,Yeo,L.Y.,Friend,J.R., and Jamriska, M.
Biomicrofluidics 3, 014102, 2009
| Page top |
Rat GH ELISA KIT
Original reports
#The CXCR4 antagonist AMD3100 suppresses hypoxia-mediated growth hormone production in GH3 rat pituitary adenoma cells
Yoshida,D.,Koketshu,K.,Nomura,R.,Teramoto,A.
J Neurooncol Published online:23 March 2010
#The CXCR4 antagonist AMD3100 suppresses hypoxia-mediated growth hormone production in GH3 rat pituitary adenoma cells
Yoshida,D.,Koketshu,K.,Nomura,R.,Teramoto,A.
J Neurooncol Published online:23 March 2010
| Page top |
Rat TSH ELISA kit (AKRTS-010)
Original reports
#Developmental PCB exposure induces hypothyroxinemia and sex-specific effects on cerebellum glial protein levels in rats
V.M. Miller., T. Kahnke., N. Neu., S.R. Sanchez-Morrissey., K. Brosch., K. Kelsey. and R.F. Seegal
International Journal of Developmental Neuroscience Vol. 28, Issue 7, November 2010, Pages 553-560
#SIRT1 Regulates Thyroid-Stimulating Hormone Release by Enhancing PIP5Kg Activity through Deacetylation of Specific Lysine Residues in Mammals
S. Akieda-Asai., N. Zaima., K. Ikegami., T. Kahyo., I. Yao., T. Hatanaka., S. Iemura., R. Sugiyama., T. Yokozeki., Y. Eishi., M. Koike., K. Ikeda., T. Chiba., H. Yamaza., I. Shimokawa., S. Y. Song., A. Matsuno., A. Mizutani., M. Sawabe., M.V. Chao., M. Tanaka., Y. Kanaho., T. Natsume., H. Sugimura., Y. Date., M. W. McBurney., L. Guarente., M. Setou.
PloS one, 2010
#Hypothyroidism of gene-targeted mice lacking Kcnq1
Henning Frohlich, Krishna M. Boini, Guiscard Seebohm, Nathalie Strutz-Seebohm, Oana N. Ureche, Michael Foller, Melanie Eichenmuller, Ekaterina Shumilina, Ganesh Pathare, Anurag Kumar Singh, Ursula Seidler, Karl E. Pfeifer, Florian Lang.
European Journal of Physiology DOI: 10.1007/s00424-010-0890-5
#Mice Lacking the Neuropeptide -Calcitonin Gene-Related Peptide Are Protected Against Diet-Induced Obesity
Christopher S. Walker, Xiaoling Li, Lynda Whiting, Sarah Glyn-Jones, Shaoping Zhang, Anthony J. Hickey, Mary A. Sewell, Katya Ruggiero, Anthony R. J. Phillips, Edward W. Kraegen, Debbie L. Hay, Garth J. S. Cooper and Kerry M. Loomes
Endocrinology Vol. 151, No. 9 4257-4269,2010
# Therapeutic Concentrations of Mitotane (o,p'-DDD) Inhibit Thyrotroph Cell Viability and TSH Expression and Secretion in a Mouse Cell Line Model
Maria Chiara Zatelli1, Erica Gentilin1, Fulvia Daffara, Federico Tagliati, Giuseppe Reimondo, Gianni Carandina, Maria Rosaria Ambrosio, Massimo Terzolo and Ettore C. degli Uberti
Endocrinology Vol.151,No.6 2453-2461,2010
#Runx2 Deficiency in Mice Causes Decreased Thyroglobulin Expression and Hypothyroidism
Toyoshi Endo and Tetsuro Kobayashi
Molecular Endocrinology24(6):1267-1273,2010
#Potential estrogenic effect(s) of parabens at the prepubertal stage of a postnatal female rat model
Thuy T.B. Voa, Yeong-Min Yooa, Kyung-Chul Choia and Eui-Bae Jeung
Reproductive Toxicology Volume29,Issue3,June 2010,Pages306-316
# Long-term thyroid hormone administration reshapes left ventricular chamber and improved cardiac function after myocardial infarction in rats.
Pantos, C., Mourouzis, I., Tsagoulis, N., Panagiotou, M., and Cokkinos, D.V.
Basic Res Cardiol, DOI 10.1007/s00395-008-0697-0, 2008
# A mutation in Tpst2 encoding tyrosylprotein sulfotransferase causes dwarfism associated with hypothyroidism.
Sasaki, N., Hosoda, Y., Nagata, A., Ding, M., Cheng, J-M., Miyamoto, T., Okano, S., Asano, A., Miyoshi, I., and Agui, T.
Mol. Endocrinol., 21: 1713-1721 , 2007
#Developmental PCB exposure induces hypothyroxinemia and sex-specific effects on cerebellum glial protein levels in rats
V.M. Miller., T. Kahnke., N. Neu., S.R. Sanchez-Morrissey., K. Brosch., K. Kelsey. and R.F. Seegal
International Journal of Developmental Neuroscience Vol. 28, Issue 7, November 2010, Pages 553-560
#SIRT1 Regulates Thyroid-Stimulating Hormone Release by Enhancing PIP5Kg Activity through Deacetylation of Specific Lysine Residues in Mammals
S. Akieda-Asai., N. Zaima., K. Ikegami., T. Kahyo., I. Yao., T. Hatanaka., S. Iemura., R. Sugiyama., T. Yokozeki., Y. Eishi., M. Koike., K. Ikeda., T. Chiba., H. Yamaza., I. Shimokawa., S. Y. Song., A. Matsuno., A. Mizutani., M. Sawabe., M.V. Chao., M. Tanaka., Y. Kanaho., T. Natsume., H. Sugimura., Y. Date., M. W. McBurney., L. Guarente., M. Setou.
PloS one, 2010
#Hypothyroidism of gene-targeted mice lacking Kcnq1
Henning Frohlich, Krishna M. Boini, Guiscard Seebohm, Nathalie Strutz-Seebohm, Oana N. Ureche, Michael Foller, Melanie Eichenmuller, Ekaterina Shumilina, Ganesh Pathare, Anurag Kumar Singh, Ursula Seidler, Karl E. Pfeifer, Florian Lang.
European Journal of Physiology DOI: 10.1007/s00424-010-0890-5
#Mice Lacking the Neuropeptide -Calcitonin Gene-Related Peptide Are Protected Against Diet-Induced Obesity
Christopher S. Walker, Xiaoling Li, Lynda Whiting, Sarah Glyn-Jones, Shaoping Zhang, Anthony J. Hickey, Mary A. Sewell, Katya Ruggiero, Anthony R. J. Phillips, Edward W. Kraegen, Debbie L. Hay, Garth J. S. Cooper and Kerry M. Loomes
Endocrinology Vol. 151, No. 9 4257-4269,2010
# Therapeutic Concentrations of Mitotane (o,p'-DDD) Inhibit Thyrotroph Cell Viability and TSH Expression and Secretion in a Mouse Cell Line Model
Maria Chiara Zatelli1, Erica Gentilin1, Fulvia Daffara, Federico Tagliati, Giuseppe Reimondo, Gianni Carandina, Maria Rosaria Ambrosio, Massimo Terzolo and Ettore C. degli Uberti
Endocrinology Vol.151,No.6 2453-2461,2010
#Runx2 Deficiency in Mice Causes Decreased Thyroglobulin Expression and Hypothyroidism
Toyoshi Endo and Tetsuro Kobayashi
Molecular Endocrinology24(6):1267-1273,2010
#Potential estrogenic effect(s) of parabens at the prepubertal stage of a postnatal female rat model
Thuy T.B. Voa, Yeong-Min Yooa, Kyung-Chul Choia and Eui-Bae Jeung
Reproductive Toxicology Volume29,Issue3,June 2010,Pages306-316
# Long-term thyroid hormone administration reshapes left ventricular chamber and improved cardiac function after myocardial infarction in rats.
Pantos, C., Mourouzis, I., Tsagoulis, N., Panagiotou, M., and Cokkinos, D.V.
Basic Res Cardiol, DOI 10.1007/s00395-008-0697-0, 2008
# A mutation in Tpst2 encoding tyrosylprotein sulfotransferase causes dwarfism associated with hypothyroidism.
Sasaki, N., Hosoda, Y., Nagata, A., Ding, M., Cheng, J-M., Miyamoto, T., Okano, S., Asano, A., Miyoshi, I., and Agui, T.
Mol. Endocrinol., 21: 1713-1721 , 2007
| Page top |
Mouse SAA ELISA kit (AKRSA-011SW)
Original reports
# CD52 is a novel costimulatory molecule for induction of CD4+ regulatory T cells.
Watanabe, T., Masuyama, J., Sohma, Y., Inazawa, H., Horie, K., Kojima, K., Uemura, Y., Aoki, Y., Kaga, S., Minota, S., Tanaka, T., Yamaguchi, Y., Kobayashi, T., and Serizawa, I.
Clin. Immunol.: 120, 247-259, 2006
# CD52 is a novel costimulatory molecule for induction of CD4+ regulatory T cells.
Watanabe, T., Masuyama, J., Sohma, Y., Inazawa, H., Horie, K., Kojima, K., Uemura, Y., Aoki, Y., Kaga, S., Minota, S., Tanaka, T., Yamaguchi, Y., Kobayashi, T., and Serizawa, I.
Clin. Immunol.: 120, 247-259, 2006
| Page top |
Assay & research materials supply
Original reports
# Dioxin detection based on immunoassay using a polyclonal antibody against octa-chlorinated dibenzo-p-dioxin (OCDD) (OCDD-HRP conjugate preparation)
Shimomura, M., Nomura, Y., Lee, K.H., Ikebukuro, K., and Karube, I.
Analyst: 126, 1207-1209, 2001
# Recombinant p51 as Antigen in an Immune Complex Transfer Enzyme Immunoassay of Immunoglobulin G Antibody to Human Immunodeficiency Virus Type 1 (Antiserum supply)
Hashinaka, K., Hashida, S., Nishikata, I., Adachi, A., Oka, S., and Eiji Ishikawa, E.
Clin Diag Lab Immunol, 7, 967-976, 2000
# Apg14p and Apg6/Vps30p Form a Protein Complex Essential for Autophagy in the Yeast, Saccharomyces cerevisiae* (Antibody supply)
Kametaka, S., Okano, T., Ohsumi, M., and Ohsumi, Y.,
J Biol Chem, Vol. 273, Issue 35, 22284-22291, August 28, 1998
# Tor-mediated Induction of Autophagy Via an Apg1 Protein Kinase Complex (Antibody supply)
Kamada, Y., Funakoshi, T., Shintani, T., Nagano, K., Ohsumi, M., and Ohsumi, Y.
J Cell Biology, Volume 150, Number 6, September 18, 2000 1507-1513
# Detection of ethylene receptor protein Cm-ERS1 during fruit development in melon
(Cucumis melo L.) (Antibody supply)
Takahashi, H., Kobayashi, T., Sato-Nara, K., Tomita, K.,and Ezura, H.
J Exp Botany, Vol. 53, No. 368, pp. 415-422, 2002
# Regulation of Prolactin and Growth Hormone Secretion Pulsatile Gonadotropin-Releasing Hormone (GnRH) Secretion Is an Inherent Function of GnRH
Neurons, as Revealed by the Culture of Medial Olfactory Placode Obtained from Embryonic Rats (Antiserum supply)
Funabashi, T., Daikoku, S., Shinohara, K., and Kimura, F.
Neuroendocrinology 71:138-144, 2000
# Differential effects of haloperidol on phencyclidine-induced reduction in substance P contents in rat brain regions (Antiserum supply)
Shirayama, Y., Mitsushio, H., Takahashi, K., and Nishikawa, T.
Neuroscience 35: 292-299, 2000
# The Cyanobacterial PilT Protein Responsible for Cell Motility and Transformation.
Okamoto and Ohmori (Antiserum supply)
Plant Cell Physiol. 43: 1127-1136, 2002
# Phytic Acid Synthesis and Vacuolar Accumulation in Suspension-Cultured Cells of...
Mitsuhashi et al. (Antiserum supply)
Plant Physiol. 138: 1607-1614, 2005
Time course of changes in the intestinal permeability of food-sensitized rats after oral allergen challenge.
(Antibody supply)
Sakamoto, Y., Ohtsuka, T., Yoshida, H., Ohto, K., Onobori, M., Matsumoto, T, Iikura, Y., and Morohoshi, T.
Pediatric Allergy Immunology 9: 20-24, 1998
# Dioxin detection based on immunoassay using a polyclonal antibody against octa-chlorinated dibenzo-p-dioxin (OCDD) (OCDD-HRP conjugate preparation)
Shimomura, M., Nomura, Y., Lee, K.H., Ikebukuro, K., and Karube, I.
Analyst: 126, 1207-1209, 2001
# Recombinant p51 as Antigen in an Immune Complex Transfer Enzyme Immunoassay of Immunoglobulin G Antibody to Human Immunodeficiency Virus Type 1 (Antiserum supply)
Hashinaka, K., Hashida, S., Nishikata, I., Adachi, A., Oka, S., and Eiji Ishikawa, E.
Clin Diag Lab Immunol, 7, 967-976, 2000
# Apg14p and Apg6/Vps30p Form a Protein Complex Essential for Autophagy in the Yeast, Saccharomyces cerevisiae* (Antibody supply)
Kametaka, S., Okano, T., Ohsumi, M., and Ohsumi, Y.,
J Biol Chem, Vol. 273, Issue 35, 22284-22291, August 28, 1998
# Tor-mediated Induction of Autophagy Via an Apg1 Protein Kinase Complex (Antibody supply)
Kamada, Y., Funakoshi, T., Shintani, T., Nagano, K., Ohsumi, M., and Ohsumi, Y.
J Cell Biology, Volume 150, Number 6, September 18, 2000 1507-1513
# Detection of ethylene receptor protein Cm-ERS1 during fruit development in melon
(Cucumis melo L.) (Antibody supply)
Takahashi, H., Kobayashi, T., Sato-Nara, K., Tomita, K.,and Ezura, H.
J Exp Botany, Vol. 53, No. 368, pp. 415-422, 2002
# Regulation of Prolactin and Growth Hormone Secretion Pulsatile Gonadotropin-Releasing Hormone (GnRH) Secretion Is an Inherent Function of GnRH
Neurons, as Revealed by the Culture of Medial Olfactory Placode Obtained from Embryonic Rats (Antiserum supply)
Funabashi, T., Daikoku, S., Shinohara, K., and Kimura, F.
Neuroendocrinology 71:138-144, 2000
# Differential effects of haloperidol on phencyclidine-induced reduction in substance P contents in rat brain regions (Antiserum supply)
Shirayama, Y., Mitsushio, H., Takahashi, K., and Nishikawa, T.
Neuroscience 35: 292-299, 2000
# The Cyanobacterial PilT Protein Responsible for Cell Motility and Transformation.
Okamoto and Ohmori (Antiserum supply)
Plant Cell Physiol. 43: 1127-1136, 2002
# Phytic Acid Synthesis and Vacuolar Accumulation in Suspension-Cultured Cells of...
Mitsuhashi et al. (Antiserum supply)
Plant Physiol. 138: 1607-1614, 2005
Time course of changes in the intestinal permeability of food-sensitized rats after oral allergen challenge.
(Antibody supply)
Sakamoto, Y., Ohtsuka, T., Yoshida, H., Ohto, K., Onobori, M., Matsumoto, T, Iikura, Y., and Morohoshi, T.
Pediatric Allergy Immunology 9: 20-24, 1998
| Former page | Page top |